Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
A | 0006470 | biological_process | protein dephosphorylation |
A | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE PSY A 501 |
Chain | Residue |
A | PHE229 |
A | ILE232 |
A | CYS403 |
A | ARG404 |
A | ALA405 |
A | GLY406 |
A | GLY408 |
A | ARG409 |
A | GLN446 |
Functional Information from PROSITE/UniProt
site_id | PS00383 |
Number of Residues | 11 |
Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. IHCraGvgRTA |
Chain | Residue | Details |
A | ILE401-ALA411 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Phosphocysteine intermediate |
Chain | Residue | Details |
A | CYS403 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 6 |
Details | Annotated By Reference To The Literature 1ytw |
Chain | Residue | Details |
A | ALA356 | |
A | THR410 | |
A | CYS403 | |
A | ARG409 | |
A | GLU290 | |
A | HIS402 | |
site_id | MCSA1 |
Number of Residues | 7 |
Details | M-CSA 47 |
Chain | Residue | Details |
A | GLU290 | steric role |
A | TRP354 | steric role |
A | ALA356 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
A | HIS402 | electrostatic stabiliser, hydrogen bond donor |
A | CYS403 | nucleofuge, nucleophile |
A | ARG409 | electrostatic stabiliser, hydrogen bond donor |
A | THR410 | electrostatic stabiliser, hydrogen bond donor |