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PDB: 12 件
7AEW
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14-3-3 sigma bound to bis-phosphorylated aminopeptidase N (APN, CD13) via canonical and non-canonical binding motifs
分子名称: 14-3-3 protein sigma, Aminopeptidase N, CHLORIDE ION, ...
著者Kiehstaller, S, Hennig, S.
登録日2020-09-18
公開日2020-11-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献MMP activation-associated aminopeptidase N reveals a bivalent 14-3-3 binding motif.
J.Biol.Chem., 295, 2020
6XWD
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BU of 6xwd by Molmil
14-3-3 sigma bound to canonical mono-phosphorylated aminopeptidase N (APN, CD13) binding motif
分子名称: 14-3-3 protein sigma, Amino peptidase N 38-46, CALCIUM ION, ...
著者Kiehstaller, S, Hennig, S.
登録日2020-01-23
公開日2020-11-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.60000193 Å)
主引用文献MMP activation-associated aminopeptidase N reveals a bivalent 14-3-3 binding motif.
J.Biol.Chem., 295, 2020
4FYT
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Human aminopeptidase N (CD13) in complex with amastatin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMASTATIN, ...
著者Wong, A.H, Rini, J.M.
登録日2012-07-05
公開日2012-09-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing.
J.Biol.Chem., 287, 2012
4FYQ
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Human aminopeptidase N (CD13)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ...
著者Wong, A.H, Rini, J.M.
登録日2012-07-05
公開日2012-09-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing.
J.Biol.Chem., 287, 2012
4FYR
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BU of 4fyr by Molmil
Human aminopeptidase N (CD13) in complex with bestatin
分子名称: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wong, A.H, Rini, J.M.
登録日2012-07-05
公開日2012-09-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing.
J.Biol.Chem., 287, 2012
4FYS
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BU of 4fys by Molmil
Human aminopeptidase N (CD13) in complex with angiotensin IV
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
著者Wong, A.H, Rini, J.M.
登録日2012-07-05
公開日2012-09-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing.
J.Biol.Chem., 287, 2012
6U7G
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HCoV-229E RBD Class V in complex with human APN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
著者Tomlinson, A, Li, Z, Rini, J.M.
登録日2019-09-02
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The human coronavirus HCoV-229E S-protein structure and receptor binding.
Elife, 8, 2019
5LHD
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BU of 5lhd by Molmil
Structure of glycosylated human aminopeptidase N
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Recacha, R, Mudgal, G, Santiago, C, Casasnovas, J.M.
登録日2016-07-11
公開日2017-04-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.
Sci Rep, 7, 2017
6U7F
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BU of 6u7f by Molmil
HCoV-229E RBD Class IV in complex with human APN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
著者Tomlinson, A.C.A, Li, Z, Rini, J.M.
登録日2019-09-02
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The human coronavirus HCoV-229E S-protein structure and receptor binding.
Elife, 8, 2019
6U7E
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BU of 6u7e by Molmil
HCoV-229E RBD Class III in complex with human APN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
著者Tomlinson, A.C.A, Li, Z, Rini, J.M.
登録日2019-09-02
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The human coronavirus HCoV-229E S-protein structure and receptor binding.
Elife, 8, 2019
7VPQ
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BU of 7vpq by Molmil
Structures of a deltacoronavirus spike protein bound to porcine and human receptors indicate the risk of virus adaptation to humans
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ji, W, Xu, Y, Zhang, S.
登録日2021-10-17
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of a deltacoronavirus spike protein bound to porcine and human receptors.
Nat Commun, 13, 2022
6ATK
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BU of 6atk by Molmil
Crystal structure of the human coronavirus 229E spike protein receptor binding domain in complex with human aminopeptidase N
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
著者Wong, A.H, Rini, J.M.
登録日2017-08-29
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.505 Å)
主引用文献Receptor-binding loops in alphacoronavirus adaptation and evolution.
Nat Commun, 8, 2017

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件を2024-07-31に公開中

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