5GUT
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![BU of 5gut by Molmil](/molmil-images/mine/5gut) | The crystal structure of mouse DNMT1 (731-1602) mutant - N1248A | 分子名称: | DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | 著者 | Chen, S.J, Ye, F. | 登録日 | 2016-08-31 | 公開日 | 2017-09-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1. ACS Chem. Biol., 13, 2018
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3PT9
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4DA4
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![BU of 4da4 by Molmil](/molmil-images/mine/4da4) | |
3AV4
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![BU of 3av4 by Molmil](/molmil-images/mine/3av4) | Crystal structure of mouse DNA methyltransferase 1 | 分子名称: | DNA (cytosine-5)-methyltransferase 1, ZINC ION | 著者 | Takeshita, K, Suetake, I, Yamashita, E, Suga, M, Narita, H, Nakagawa, A, Tajima, S. | 登録日 | 2011-02-22 | 公開日 | 2011-05-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1). Proc.Natl.Acad.Sci.USA, 108, 2011
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6W8W
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![BU of 6w8w by Molmil](/molmil-images/mine/6w8w) | Crystal structure of mouse DNMT1 in complex with CCG DNA | 分子名称: | CCG DNA (5'-D(*AP*CP*TP*TP*AP*(5CM)P*GP*GP*AP*AP*GP*G)-3'), CCG DNA (5'-D(*CP*CP*TP*TP*CP*(C49)P*GP*TP*AP*AP*GP*T)-3'), DNA (cytosine-5)-methyltransferase 1, ... | 著者 | Anteneh, H, Song, J. | 登録日 | 2020-03-21 | 公開日 | 2020-07-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | DNMT1 activity, base flipping mechanism and genome-wide DNA methylation are regulated by the DNA sequence context Nat Commun, 2020
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3PT6
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![BU of 3pt6 by Molmil](/molmil-images/mine/3pt6) | Crystal structure of mouse DNMT1(650-1602) in complex with DNA | 分子名称: | DNA (5'-D(*CP*CP*TP*GP*CP*GP*GP*AP*GP*GP*CP*TP*CP*AP*CP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*CP*CP*GP*CP*AP*GP*G)-3'), DNA (cytosine-5)-methyltransferase 1, ... | 著者 | Song, J, Patel, D.J. | 登録日 | 2010-12-02 | 公開日 | 2010-12-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science, 331, 2011
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5GUV
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3AV6
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![BU of 3av6 by Molmil](/molmil-images/mine/3av6) | Crystal structure of mouse DNA methyltransferase 1 with AdoMet | 分子名称: | DNA (cytosine-5)-methyltransferase 1, S-ADENOSYLMETHIONINE, ZINC ION | 著者 | Takeshita, K, Suetake, I, Yamashita, E, Suga, M, Narita, H, Nakagawa, A, Tajima, S. | 登録日 | 2011-02-22 | 公開日 | 2011-05-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1). Proc.Natl.Acad.Sci.USA, 108, 2011
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6W8V
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![BU of 6w8v by Molmil](/molmil-images/mine/6w8v) | Crystal structure of mouse DNMT1 in complex with ACG DNA | 分子名称: | ACG DNA (5'-D(*AP*CP*TP*TP*AP*(C49)P*GP*GP*AP*AP*GP*G)-3'), ACG DNA (5'-D(*CP*CP*TP*TP*CP*(5CM)P*GP*TP*AP*AP*GP*T)-3'), DNA (cytosine-5)-methyltransferase 1, ... | 著者 | Anteneh, H, Song, J. | 登録日 | 2020-03-21 | 公開日 | 2020-07-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | DNMT1 activity, base flipping mechanism and genome-wide DNA methylation are regulated by the DNA sequence context Nat Commun, 2020
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3AV5
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![BU of 3av5 by Molmil](/molmil-images/mine/3av5) | Crystal structure of mouse DNA methyltransferase 1 with AdoHcy | 分子名称: | DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | 著者 | Takeshita, K, Suetake, I, Yamashita, E, Suga, M, Narita, H, Nakagawa, A, Tajima, S. | 登録日 | 2011-02-22 | 公開日 | 2011-05-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1). Proc.Natl.Acad.Sci.USA, 108, 2011
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5WY1
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![BU of 5wy1 by Molmil](/molmil-images/mine/5wy1) | Crystal structure of mouse DNA methyltransferase 1 (T1505A mutant) | 分子名称: | DNA (cytosine-5)-methyltransferase 1, ZINC ION | 著者 | Kanada, K, Takeshita, K, Suetake, I, Tajima, S, Nakagawa, A. | 登録日 | 2017-01-10 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.27 Å) | 主引用文献 | Conserved threonine 1505 in the catalytic domain stabilizes mouse DNA methyltransferase 1 J. Biochem., 162, 2017
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