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PDB: 15 件
3POM
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Crystal Structure of the Unliganded Retinoblastoma Protein Pocket Domain
分子名称: Retinoblastoma-associated protein
著者Balog, E.R.M, Burke, J.R, Rubin, S.M.
登録日2010-11-23
公開日2011-04-27
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the unliganded retinoblastoma protein pocket domain.
Proteins, 79, 2011
4CRI
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Crystal Structure of 53BP1 tandem tudor domains in complex with methylated K810 Rb peptide
分子名称: RB1 PROTEIN, TUMOR SUPPRESSOR P53-BINDING PROTEIN 1
著者Krojer, T, Johansson, C, Gileadi, C, Fedorov, O, Carr, S, La Thangue, N.B, Vollmar, M, Crawley, L, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U.
登録日2014-02-26
公開日2014-08-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Lysine Methylation-Dependent Binding of 53BP1 to the Prb Tumor Suppressor.
Proc.Natl.Acad.Sci.USA, 111, 2014
4ELJ
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Crystal structure of the inactive retinoblastoma protein phosphorylated at T373
分子名称: Retinoblastoma-associated protein
著者Burke, J.R, Rubin, S.M.
登録日2012-04-10
公開日2012-05-23
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control.
Genes Dev., 26, 2012
1AD6
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DOMAIN A OF HUMAN RETINOBLASTOMA TUMOR SUPPRESSOR
分子名称: RETINOBLASTOMA TUMOR SUPPRESSOR
著者Kim, H.Y, Cho, Y.
登録日1997-02-21
公開日1998-08-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural similarity between the pocket region of retinoblastoma tumour suppressor and the cyclin-box.
Nat.Struct.Biol., 4, 1997
3N5U
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Crystal structure of an Rb C-terminal peptide bound to the catalytic subunit of PP1
分子名称: CHLORIDE ION, MANGANESE (II) ION, Retinoblastoma-associated protein, ...
著者Hirschi, A.M, Cecchini, M, Steinhardt, R.C, Dick, F.A, Rubin, S.M.
登録日2010-05-25
公開日2010-08-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein.
Nat.Struct.Mol.Biol., 17, 2010
2QDJ
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Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture
分子名称: Retinoblastoma-associated protein
著者Hassler, M, Mittnacht, S, Pearl, L.H.
登録日2007-06-21
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture.
Mol.Cell, 28, 2007
1GUX
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RB POCKET BOUND TO E7 LXCXE MOTIF
分子名称: ONCOPROTEIN, RETINOBLASTOMA PROTEIN
著者Lee, J.O, Russo, A.A, Pavletich, N.P.
登録日1997-11-15
公開日1998-12-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7.
Nature, 391, 1998
4ELL
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BU of 4ell by Molmil
Structure of the inactive retinoblastoma protein pocket domain
分子名称: Retinoblastoma-associated protein
著者Burke, J.R, Rubin, S.M.
登録日2012-04-10
公開日2012-05-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control.
Genes Dev., 26, 2012
1N4M
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BU of 1n4m by Molmil
Structure of Rb tumor suppressor bound to the transactivation domain of E2F-2
分子名称: Retinoblastoma Pocket, Transcription factor E2F2
著者Lee, C, Chang, J.H, Lee, H.S, Cho, Y.
登録日2002-10-31
公開日2003-01-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor
GENES DEV., 16, 2002
2R7G
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BU of 2r7g by Molmil
Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain
分子名称: Early E1A 32 kDa protein, Retinoblastoma-associated protein, SULFATE ION
著者Liu, X, Marmorstein, R.
登録日2007-09-07
公開日2007-10-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.671 Å)
主引用文献Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor
Genes Dev., 21, 2007
2AZE
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BU of 2aze by Molmil
Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
分子名称: Retinoblastoma-associated protein, Transcription factor Dp-1, Transcription factor E2F1
著者Rubin, S.M, Gall, A.L, Zheng, N, Pavletich, N.P.
登録日2005-09-10
公開日2006-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.
Cell(Cambridge,Mass.), 123, 2005
1O9K
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Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide
分子名称: RETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1
著者Xiao, B, Spencer, J, Clements, A, Ali-Khan, N, Mittnacht, S, Broceno, C, Burghammer, M, Perrakis, A, Marmorstein, R, Gamblin, S.J.
登録日2002-12-16
公開日2003-03-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation
Proc.Natl.Acad.Sci.USA, 100, 2003
1PJM
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BU of 1pjm by Molmil
Mouse Importin alpha-bipartite NLS from human retinoblastoma protein Complex
分子名称: Importin alpha-2 subunit, Retinoblastoma-associated protein
著者Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B.
登録日2003-06-03
公開日2003-08-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha
J.Biol.Chem., 278, 2003
1GH6
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RETINOBLASTOMA POCKET COMPLEXED WITH SV40 LARGE T ANTIGEN
分子名称: Large T antigen, Retinoblastoma-associated protein
著者Kim, H.Y, Cho, Y.
登録日2000-11-15
公開日2001-11-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen.
EMBO J., 20, 2001
1H25
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CDK2/Cyclin A in complex with an 11-residue recruitment peptide from retinoblastoma-associated protein
分子名称: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, RETINOBLASTOMA-ASSOCIATED PROTEIN
著者Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N.
登録日2002-07-31
公開日2003-02-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Biochemistry, 41, 2002

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