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PDB: 24 件

1GP0
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Human IGF2R domain 11
分子名称: CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, SULFATE ION
著者Brown, J, Esnouf, R.M, Jones, M.A, Linnell, J, Harlos, K, Hassan, A.B, Jones, E.Y.
登録日2001-10-29
公開日2002-02-28
最終更新日2019-04-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of a Functional Igf2R Fragment Determined from the Anomalous Scattering of Sulfur
Embo J., 21, 2002
6Z30
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Human cation-independent mannose 6-phosphate/ IGF2 receptor domains 9-10
分子名称: Cation-independent mannose-6-phosphate receptor, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Bochel, A.J, Williams, C, Crump, M.P.
登録日2020-05-19
公開日2020-08-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.
Structure, 28, 2020
1E6F
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Human MIR-receptor, repeat 11
分子名称: CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
著者Von Buelow, R, Rajashankar, K.R, Dauter, M, Dauter, Z, Grimme, S, Schmidt, B, Von Figura, K, Uson, I.
登録日2000-08-15
公開日2001-08-09
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Locating the Anomalous Scatterer Substructures in Halide and Sulfur Phasing
Acta Crystallogr.,Sect.D, 59, 2003
1GQB
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HUMAN MIR-RECEPTOR, REPEAT 11
分子名称: BROMIDE ION, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
著者Von Buelow, R, Dauter, M, Dauter, Z, Rajashankar, K.R, Grimme, S, Schmidt, B, Von Figura, K, Uson, I.
登録日2001-11-22
公開日2002-12-05
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Locating the Anomalous Scatterer Substructures in Halide and Sulfur Phasing
Acta Crystallogr.,Sect.D, 59, 2003
1GP3
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Human IGF2R domain 11
分子名称: CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
著者Brown, J, Esnouf, R.M, Jones, M.A, Linnell, J, Harlos, K, Hassan, A.B, Jones, E.Y.
登録日2001-10-29
公開日2002-02-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of a Functional Igf2R Fragment Determined from the Anomalous Scattering of Sulfur
Embo J., 21, 2002
1JWG
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VHS Domain of human GGA1 complexed with cation-independent M6PR C-terminal Peptide
分子名称: ADP-ribosylation factor binding protein GGA1, Cation-independent mannose-6-phosphate receptor, IODIDE ION
著者Shiba, T, Takatsu, H, Nogi, T, Matsugaki, N, Kawasaki, M, Igarashi, N, Suzuki, M, Kato, R, Earnest, T, Nakayama, K, Wakatsuki, S.
登録日2001-09-04
公開日2002-03-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for recognition of acidic-cluster dileucine sequence by GGA1.
Nature, 415, 2002
6N5X
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Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1)
分子名称: GLYCEROL, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), Sorting nexin-5,Cation-independent mannose-6-phosphate receptor
著者Collins, B, Paul, B, Weeratunga, S.
登録日2018-11-22
公開日2019-09-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.051 Å)
主引用文献Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
6N5Y
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Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1)
分子名称: Sorting nexin-5,Cation-independent mannose-6-phosphate receptor
著者Collins, B, Paul, B, Weeratunga, S.
登録日2018-11-22
公開日2019-09-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
1LF8
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Complex of GGA3-VHS Domain and CI-MPR C-terminal Phosphopeptide
分子名称: ADP-ribosylation factor binding protein GGA3, Cation-independent mannose-6-phosphate receptor
著者Kato, Y, Misra, S, Puertollano, R, Hurley, J.H, Bonifacino, J.S.
登録日2002-04-10
公開日2002-06-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Phosphoregulation of sorting signal-VHS domain interactions by a direct electrostatic mechanism.
Nat.Struct.Biol., 9, 2002
1JPL
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GGA3 VHS domain complexed with C-terminal peptide from cation-independent mannose 6-phosphate receptor
分子名称: ADP-RIBOSYLATION FACTOR BINDING PROTEIN GGA3, Cation-Independent Mannose 6-phosphate receptor
著者Misra, S, Puertollano, R, Bonifacino, J.S, Hurley, J.H.
登録日2001-08-02
公開日2002-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains.
Nature, 415, 2002
6V02
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N-terminal 5 domains of CI-MPR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cation-independent mannose-6-phosphate receptor
著者Olson, L.J, Dahms, N.M, Kim, J.-J.P.
登録日2019-11-18
公開日2020-09-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor.
Commun Biol, 3, 2020
6P8I
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N-terminal 5 domains of IGFIIR
分子名称: Cation-independent mannose-6-phosphate receptor, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Olson, L.J, Dahms, N.M, Kim, J.-J.P.
登録日2019-06-07
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor.
Commun Biol, 3, 2020
6Z31
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Human cation-independent mannose 6-phosphate/ IGF2 receptor domain 8
分子名称: CHLORIDE ION, Cation-independent mannose-6-phosphate receptor, SODIUM ION
著者Bochel, A.J, Williams, C, Crump, M.P.
登録日2020-05-19
公開日2020-08-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.
Structure, 28, 2020
5IEI
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BU of 5iei by Molmil
X-ray crystallographic structure of a high affinity IGF2 antagonist (Domain11 AB5 RHH) based on human IGF2R domain 11
分子名称: 1,2-ETHANEDIOL, Cation-independent mannose-6-phosphate receptor, GLYCEROL, ...
著者Nicholls, R.D, Williams, C, Strickland, M, Frago, S, Hassan, A.B, Crump, M.P.
登録日2016-02-25
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016
2V5O
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STRUCTURE OF HUMAN IGF2R DOMAINS 11-14
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, CHLORIDE ION
著者Brown, J, Delaine, C, Zaccheo, O.J, Siebold, C, Gilbert, R.J, van Boxel, G, Denley, A, Wallace, J.C, Hassan, A.B, Forbes, B.E, Jones, E.Y.
登録日2007-07-06
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Structure and Functional Analysis of the Igf-II/Igf2R Interaction
Embo J., 27, 2008
2V5N
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STRUCTURE OF HUMAN IGF2R DOMAINS 11-12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
著者Brown, J, Delaine, C, Zaccheo, O.J, Siebold, C, Gilbert, R.J, van Boxel, G, Denley, A, Wallace, J.C, Hassan, A.B, Forbes, B.E, Jones, E.Y.
登録日2007-07-06
公開日2007-12-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and Functional Analysis of the Igf-II/Igf2R Interaction
Embo J., 27, 2008
6Z32
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Human cation-independent mannose 6-phosphate/IGF2 receptor domains 7-11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cation-independent mannose-6-phosphate receptor, SULFATE ION, ...
著者Bochel, A.J, Williams, C, McCoy, A.J, Hoppe, H, Winter, A.J, Nicholls, R.D, Harlos, K, Jones, Y.E, Berger, I, Hassan, B, Crump, M.P.
登録日2020-05-19
公開日2020-08-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.47 Å)
主引用文献Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.
Structure, 28, 2020
2V5P
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COMPLEX STRUCTURE OF HUMAN IGF2R DOMAINS 11-13 BOUND TO IGF-II
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, INSULIN-LIKE GROWTH FACTOR II, ...
著者Brown, J, Delaine, C, Zaccheo, O.J, Siebold, C, Gilbert, R.J, van Boxel, G, Denley, A, Wallace, J.C, Hassan, A.B, Forbes, B.E, Jones, E.Y.
登録日2007-07-06
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structure and Functional Analysis of the Igf-II/Igf2R Interaction
Embo J., 27, 2008
8AFZ
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Architecture of the ESCPE-1 membrane coat
分子名称: Cation-independent mannose-6-phosphate receptor, Sorting nexin-1, Sorting nexin-5
著者Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E, Ishida, M, Williamsom, C.D, Banos-Mateos, S, Gil-Carton, D, Romero, M, Vidaurrazaga, A, Fernandez-Recio, J, Rojas, A.L, Bonifacino, J.S, Castano-Diez, D, Hierro, A.
登録日2022-07-18
公開日2023-06-21
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Architecture of the ESCPE-1 membrane coat.
Nat.Struct.Mol.Biol., 30, 2023
2L29
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Complex structure of E4 mutant human IGF2R domain 11 bound to IGF-II
分子名称: Insulin-like growth factor 2 receptor variant, Insulin-like growth factor II
著者Williams, C, Hoppe, H, Rezgui, D, Strickland, M, Frago, S, Ellis, R.Z, Wattana-Amorn, P, Prince, S.N, Zaccheo, O.J, Forbes, B, Jones, E.Y, Crump, M.P, Hassan, A.B.
登録日2010-08-13
公開日2012-02-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science, 338, 2012
2M68
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NMR solution structure ensemble of 3-4D mutant domain 11 IGF2R in complex with IGF2 (domain 11 structure only)
分子名称: Insulin-like growth factor 2 receptor variant
著者Strickland, M, Williams, C, Richards, E, Minnall, L, Crump, M.P, Frago, S, Hughes, J, Garner, L, Hoppe, H, Rezgui, D, Zaccheo, O.J, Prince, S.N, Hassan, A.B, Whittaker, S.
登録日2013-03-27
公開日2014-10-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016
2CNJ
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NMR studies on the interaction of Insulin-Growth Factor II (IGF-II) with IGF2R domain 11
分子名称: CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
著者Williams, C, Prince, S, Zaccheo, O, Hassan, A.B, Crosby, J, Crump, M.
登録日2006-05-22
公開日2007-05-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Insights Into the Interaction of Insulin-Like Growth Factor 2 with Igf2R Domain 11.
Structure, 15, 2007
2L2A
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Mutated Domain 11 of the Cytoplasmic region of the Cation-independent mannose-6-phosphate receptor
分子名称: Insulin-like growth factor 2 receptor variant
著者Williams, C, Hoppe, H, Rezgui, D, Strickland, M, Frago, S, Ellis, R.Z, Wattana-Amorn, P, Prince, S.N, Zaccheo, O.J, Forbes, B, Jones, E.Y, Crump, M.P, Hassan, A.B.
登録日2010-08-13
公開日2012-02-15
最終更新日2012-12-12
実験手法SOLUTION NMR
主引用文献An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science, 338, 2012
2M6T
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BU of 2m6t by Molmil
NMR solution structure ensemble of 3-4D mutant domain 11 IGF2R
分子名称: Insulin-like growth factor 2 receptor variant
著者Strickland, M, Williams, C, Richards, E, Minnall, L, Crump, M.P, Frago, S, Hughes, J, Garner, L, Hoppe, H, Rezgui, D, Zaccheo, O.J, Prince, S.N, Hassan, A.B, Whittaker, S.
登録日2013-04-09
公開日2014-10-15
最終更新日2016-06-01
実験手法SOLUTION NMR
主引用文献Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc.Natl.Acad.Sci.USA, 113, 2016

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