8X50
 
 | | BA.2.86 Spike Trimer with ins483V mutation (1 RBD up) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yue, C, Liu, P. | | 登録日 | 2023-11-16 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity
Natl Sci Rev, 2024
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8T22
 | | Cryo-EM structure of mink variant Y453F trimeric spike protein bound to one mink ACE2 receptors at downRBD conformation | | 分子名称: | Angiotensin-converting enzyme, Spike glycoprotein | | 著者 | Ahn, H.M, Calderon, B, Fan, X, Gao, Y, Horgan, N, Zhou, B, Liang, B. | | 登録日 | 2023-06-05 | | 公開日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.83 Å) | | 主引用文献 | Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2.
J Med Virol, 95, 2023
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8CSA
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7YQZ
 | | SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state3) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, S309 light chain, ... | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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7BYR
 | | BD23-Fab in complex with the S ectodomain trimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab23-Fab-Heavy Chain, ... | | 著者 | Zhu, Q, Wang, G, Xiao, J. | | 登録日 | 2020-04-24 | | 公開日 | 2020-06-10 | | 最終更新日 | 2021-03-10 | | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | | 主引用文献 | Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells.
Cell, 182, 2020
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7KEC
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8XUR
 | | BA.2.86 Spike Trimer in complex with heparan sulfate | | 分子名称: | 2-O-sulfo-beta-L-altropyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yue, C, Liu, P. | | 登録日 | 2024-01-14 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity
Natl Sci Rev, 2024
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7V26
 | | XG005-bound SARS-CoV-2 S | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, XG005 Heavy chain, ... | | 著者 | Zhan, W.Q, Zhang, X, Sun, L, Chen, Z.G. | | 登録日 | 2021-08-07 | | 公開日 | 2021-10-20 | | 最終更新日 | 2022-07-06 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | An ultrapotent pan-beta-coronavirus lineage B ( beta-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.
Protein Cell, 13, 2022
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8PQ2
 | | XBB 1.0 RBD bound to P4J15 (Local) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, P4J15 Fragment Antigen-Binding Heavy Chain, P4J15 Fragment Antigen-Binding Light Chain, ... | | 著者 | Duhoo, Y, Lau, K. | | 登録日 | 2023-07-10 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeys.
J Infect, 87, 2023
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7KNE
 | | Cryo-EM structure of single ACE2-bound SARS-CoV-2 trimer spike at pH 5.5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L. | | 登録日 | 2020-11-04 | | 公開日 | 2020-12-16 | | 最終更新日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
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8DAD
 | | SARS-CoV-2 receptor binding domain in complex with AZ090 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AZ090 Fab Heavy Chain, AZ090 Fab Light Chain, ... | | 著者 | Zong, S, Wang, Z, Gaebler, C, Nussenzweig, M. | | 登録日 | 2022-06-13 | | 公開日 | 2022-08-24 | | 最終更新日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | SARS-CoV-2 receptor binding domain in complex with AZ090 Fab
To Be Published
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7TCA
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8I9C
 | | S-ECD (Omicron BF.7) in complex with PD of ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | | 著者 | Li, Y.N, Shen, Y.P, Zhang, Y.Y, Yan, R.H. | | 登録日 | 2023-02-06 | | 公開日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | Structural basis for the enhanced infectivity and immune evasion of Omicron subvariants
To Be Published
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8WHW
 | | Spike Trimer of BA.2.86 with single RBD up | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yue, C, Liu, P. | | 登録日 | 2023-09-23 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity
Natl Sci Rev, 2024
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7U0Q
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7TCC
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8T23
 | | Cryo-EM structure of the RBD-ACE2 interface of the SARS-CoV-2 trimeric spike protein bound to ACE2 receptor after local refinement at upRBD conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | 著者 | Ahn, H.M, Calderon, B, Fan, X, Gao, Y, Horgan, N, Zhou, B, Liang, B. | | 登録日 | 2023-06-05 | | 公開日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2.
J Med Virol, 95, 2023
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7WOV
 | | The state 5 of Omicron Spike with bispecific antibody FD01 | | 分子名称: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ... | | 著者 | Zhang, X, Zhan, W.Q, Sun, L, Chen, Z.G. | | 登録日 | 2022-01-22 | | 公開日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
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7TPL
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7THE
 | | Structure of RBD directed antibody DH1042 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interface | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1042 Fab Heavy Chain, DH1042 Fab Light Chain, ... | | 著者 | May, A.J, Manne, K, Acharya, P. | | 登録日 | 2022-01-10 | | 公開日 | 2022-02-16 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Structural diversity of the SARS-CoV-2 Omicron spike.
Mol.Cell, 82, 2022
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7XRP
 | | Cryo-EM structure of SARS-CoV-2 spike protein in complex with nanobody C5G2 (localized refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C5G2 nanobody, Spike protein S1 | | 著者 | Liu, L, Sun, H, Jiang, Y, Liu, X, Zhao, D, Zheng, Q, Li, S, Xia, N. | | 登録日 | 2022-05-11 | | 公開日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.88 Å) | | 主引用文献 | A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode.
J Nanobiotechnology, 20, 2022
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8SWH
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7QO9
 | | SARS-CoV-2 S Omicron Spike B.1.1.529 - RBD and NTD (Local) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,SARS-CoV-2 S Omicron Spike B.1.1.529, ... | | 著者 | Ni, D, Lau, K, Turelli, P, Beckert, B, Nazarov, S, Pojer, F, Myasnikov, A, Stahlberg, H, Trono, D. | | 登録日 | 2021-12-23 | | 公開日 | 2022-01-26 | | 実験手法 | ELECTRON MICROSCOPY (3.88 Å) | | 主引用文献 | Structural analysis of the Spike of the Omicron SARS-COV-2 variant by cryo-EM and implications for immune evasion
Biorxiv, 2021
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7WP8
 | | Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK1628x in complex with three neutralizing antibodies | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 heavy chain, ... | | 著者 | Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N. | | 登録日 | 2022-01-23 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | ELECTRON MICROSCOPY (3.88 Å) | | 主引用文献 | Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.
Cell Host Microbe, 30, 2022
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7LRS
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