8CKU
| Translocation intermediate 1 (TI-1*) of 80S S. cerevisiae ribosome with ligands and eEF2 in the absence of sordarin | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | 登録日 | 2023-02-16 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
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5DAT
| Complex of yeast 80S ribosome with hypusine-containing eIF5A | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | 登録日 | 2015-08-20 | 公開日 | 2016-08-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
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8P4V
| 80S yeast ribosome in complex with HaterumaimideQ | 分子名称: | (3~{R})-3-[(1~{S})-2-[(1~{R},3~{S},4~{a}~{S},8~{a}~{S})-5,5,8~{a}-trimethyl-2-methylidene-3-oxidanyl-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Terrosu, S, Yusupov, M. | 登録日 | 2023-05-23 | 公開日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | 主引用文献 | Role of Protein eL42 in the Ribosome Binding of Synthetic Analogues of Natural Lissoclimides To Be Published
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4U51
| Crystal structure of Narciclasine bound to the yeast 80S ribosome | 分子名称: | (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
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4U3N
| Crystal structure of CCA trinucleotide bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-22 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
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4U55
| Crystal structure of Cryptopleurine bound to the yeast 80S ribosome | 分子名称: | (14aR)-2,3,6-trimethoxy-11,12,13,14,14a,15-hexahydro-9H-dibenzo[f,h]pyrido[1,2-b]isoquinoline, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
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6LQP
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6XIR
| Cryo-EM Structure of K63 Ubiquitinated Yeast Translocating Ribosome under Oxidative Stress | 分子名称: | 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Zhou, Y, Bartesaghi, A, Silva, G.M. | 登録日 | 2020-06-21 | 公開日 | 2020-08-26 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proc.Natl.Acad.Sci.USA, 117, 2020
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8K2D
| Cryo-EM structure of the yeast 80S ribosome with tigecycline, eEF2, Stm1 and eIF5A | 分子名称: | 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Buschauer, R, Beckmann, R, Cheng, J. | 登録日 | 2023-07-12 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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6T7I
| Structure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination. | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | 登録日 | 2019-10-22 | 公開日 | 2019-12-25 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
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4U50
| Crystal structure of Verrucarin bound to the yeast 80S ribosome | 分子名称: | (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4-hydroxy-5,16a,21-trimethyl-4,5,6,7,16,16a,22,23-octahydro-3H,18H,19aH-spiro[16,18-methano[1,6,12]trioxacyclooctadecino[3,4-d]chromene-17,2'-oxirane]-3,9,14-trione, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
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4U4Y
| Crystal structure of Pactamycin bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
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5LYB
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5DC3
| Complex of yeast 80S ribosome with non-modified eIF5A | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | 登録日 | 2015-08-23 | 公開日 | 2016-06-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome. J.Mol.Biol., 428, 2016
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6S47
| Saccharomyces cerevisiae 80S ribosome bound with ABCF protein New1 | 分子名称: | 18S rRNA (1707-MER), 28S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Kasari, V, Pochopien, A.A, Margus, T, Murina, V, Turnbull, K, Zhou, Y, Nissan, T, Graf, M, Novacek, J, Atkinson, G.C, Johansson, M.J.O, Wilson, D.N, Hauryliuk, V. | 登録日 | 2019-06-26 | 公開日 | 2019-07-24 | 最終更新日 | 2019-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling. Nucleic Acids Res., 47, 2019
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4U53
| Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome | 分子名称: | (3beta,7alpha)-3,7,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
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7B7D
| Yeast 80S ribosome bound to eEF3 and A/A- and P/P-tRNAs | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | 著者 | Ranjan, N, Pochopien, A.A, Wu, C.C, Beckert, B, Blanchet, S, Green, R, Rodnina, M.V, Wilson, D.N. | 登録日 | 2020-12-10 | 公開日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | eEF3 promotes late stages of tRNA translocation including E-tRNA release from the ribosome To Be Published
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5NDV
| Crystal structure of Paromomycin bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | 登録日 | 2017-03-09 | 公開日 | 2017-12-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7WTL
| Cryo-EM structure of a yeast pre-40S ribosomal subunit - State Dis-D | 分子名称: | 18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... | 著者 | Cheng, J, La Venuta, G, Lau, B, Berninghausen, O, Beckmann, R, Hurt, E. | 登録日 | 2022-02-05 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | In vitro structural maturation of an early stage pre-40S particle coupled with U3 snoRNA release and central pseudoknot formation. Nucleic Acids Res., 50, 2022
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5DGF
| Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | 登録日 | 2015-08-27 | 公開日 | 2016-12-14 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
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5TGA
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5M1J
| Nonstop ribosomal complex bound with Dom34 and Hbs1 | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Hilal, T, Yamamoto, H, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T. | 登録日 | 2016-10-07 | 公開日 | 2017-01-18 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution. Nat Commun, 7, 2016
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6SV4
| The cryo-EM structure of SDD1-stalled collided trisome. | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | 著者 | Tesina, P, Buschauer, R, Cheng, J, Becker, T, Beckmann, R. | 登録日 | 2019-09-17 | 公開日 | 2020-03-04 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1. Nat.Struct.Mol.Biol., 27, 2020
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6KE6
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5OBM
| Crystal structure of Gentamicin bound to the yeast 80S ribosome | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | 登録日 | 2017-06-28 | 公開日 | 2017-12-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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