6UU0
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![BU of 6uu0 by Molmil](/molmil-images/mine/6uu0) | E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching GTP ("Fresh" crystal soaked with GTP for 1 hour) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zuo, Y, De, S, Steitz, T.A. | 登録日 | 2019-10-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6B6H
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![BU of 6b6h by Molmil](/molmil-images/mine/6b6h) | The cryo-EM structure of a bacterial class I transcription activation complex | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Liu, B, Hong, C, Huang, R, Yu, Z, Steitz, T.A. | 登録日 | 2017-10-02 | 公開日 | 2017-11-15 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of bacterial transcription activation. Science, 358, 2017
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6PSU
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![BU of 6psu by Molmil](/molmil-images/mine/6psu) | Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi2) with TraR and rpsT P2 promoter | 分子名称: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | 登録日 | 2019-07-13 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
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6Z9P
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![BU of 6z9p by Molmil](/molmil-images/mine/6z9p) | Transcription termination intermediate complex 1 | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Said, N, Hilal, T, Loll, B, Wahl, M.C. | 登録日 | 2020-06-04 | 公開日 | 2020-11-04 | 最終更新日 | 2021-02-03 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho. Science, 371, 2021
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8G7E
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![BU of 8g7e by Molmil](/molmil-images/mine/8g7e) | Cryo-EM structure of 3DVA component 0 of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand | 分子名称: | 7-DEAZA-7-AMINOMETHYL-GUANINE, DNA (31-MER), DNA (39-mer), ... | 著者 | Porta, J.C, Chauvier, A, Deb, I, Ellinger, E, Frank, A.T, Meze, K, Ohi, M.D, Walter, N.G. | 登録日 | 2023-02-16 | 公開日 | 2023-06-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand. Nat.Struct.Mol.Biol., 30, 2023
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6ZTN
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![BU of 6ztn by Molmil](/molmil-images/mine/6ztn) | E. coli 70S-RNAP expressome complex in NusG-coupled state (42 nt intervening mRNA) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Webster, M.W, Takacs, M, Weixlbaumer, A. | 登録日 | 2020-07-20 | 公開日 | 2020-09-16 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
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8FIX
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![BU of 8fix by Molmil](/molmil-images/mine/8fix) | Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex harboring a terminal mismatch | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C. | 登録日 | 2022-12-17 | 公開日 | 2023-03-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186, 2023
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8RED
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![BU of 8red by Molmil](/molmil-images/mine/8red) | |
6X2N
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![BU of 6x2n by Molmil](/molmil-images/mine/6x2n) | Mfd-bound E.coli RNA polymerase elongation complex - I state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | 登録日 | 2020-05-20 | 公開日 | 2021-02-03 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase. Elife, 10, 2021
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4JK1
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![BU of 4jk1 by Molmil](/molmil-images/mine/4jk1) | |
4MEX
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![BU of 4mex by Molmil](/molmil-images/mine/4mex) | Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. | 登録日 | 2013-08-27 | 公開日 | 2014-05-21 | 最終更新日 | 2014-06-25 | 実験手法 | X-RAY DIFFRACTION (3.902 Å) | 主引用文献 | Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife, 3, 2014
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6PMJ
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![BU of 6pmj by Molmil](/molmil-images/mine/6pmj) | |
5UAJ
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![BU of 5uaj by Molmil](/molmil-images/mine/5uaj) | Escherichia coli RNA polymerase RpoB S531L mutant | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Molodtsov, V, Scharf, N.T, Stefan, M.A, Garcia, G.A, Murakami, K.S. | 登録日 | 2016-12-19 | 公開日 | 2017-01-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.915 Å) | 主引用文献 | Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis. Mol. Microbiol., 103, 2017
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4MEY
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![BU of 4mey by Molmil](/molmil-images/mine/4mey) | Crystal structure of Escherichia coli RNA polymerase holoenzyme | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. | 登録日 | 2013-08-27 | 公開日 | 2014-05-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.948 Å) | 主引用文献 | Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife, 3, 2014
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6UUB
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![BU of 6uub by Molmil](/molmil-images/mine/6uub) | E. coli sigma-S transcription initiation complex with a mismatching UTP ("Fresh" crystal soaked with UTP for 2 hours) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zuo, Y, De, S, Steitz, T.A. | 登録日 | 2019-10-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.955 Å) | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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4KN4
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![BU of 4kn4 by Molmil](/molmil-images/mine/4kn4) | |
8Y6U
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![BU of 8y6u by Molmil](/molmil-images/mine/8y6u) | |
4ZH4
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![BU of 4zh4 by Molmil](/molmil-images/mine/4zh4) | |
7Q0K
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![BU of 7q0k by Molmil](/molmil-images/mine/7q0k) | RNA polymerase elongation complex in less-swiveled conformation | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | 登録日 | 2021-10-15 | 公開日 | 2022-03-23 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium. Nat Commun, 13, 2022
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7VWZ
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![BU of 7vwz by Molmil](/molmil-images/mine/7vwz) | Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Lin, W, Feng, Y, Shi, J. | 登録日 | 2021-11-12 | 公開日 | 2022-06-08 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator. Nucleic Acids Res., 50, 2022
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7ADC
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![BU of 7adc by Molmil](/molmil-images/mine/7adc) | Transcription termination intermediate complex 3 delta NusG | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ... | 著者 | Said, N, Hilal, T, Loll, B, Wahl, C.M. | 登録日 | 2020-09-14 | 公開日 | 2020-11-25 | 最終更新日 | 2021-02-03 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho. Science, 371, 2021
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6X2F
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![BU of 6x2f by Molmil](/molmil-images/mine/6x2f) | Mfd-bound E.coli RNA polymerase elongation complex - L2 state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | 登録日 | 2020-05-20 | 公開日 | 2021-02-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase. Elife, 10, 2021
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6UUA
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![BU of 6uua by Molmil](/molmil-images/mine/6uua) | E. coli sigma-S transcription initiation complex with a mismatching CTP ("Fresh" crystal soaked with CTP for 2 hours) | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Zuo, Y, De, S, Steitz, T.A. | 登録日 | 2019-10-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.002 Å) | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UU3
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![BU of 6uu3 by Molmil](/molmil-images/mine/6uu3) | E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Old" crystal soaked with GTP, ATP, CTP, and ddTTP for 30 minutes) | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Zuo, Y, De, S, Steitz, T.A. | 登録日 | 2019-10-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.002 Å) | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6JBQ
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![BU of 6jbq by Molmil](/molmil-images/mine/6jbq) | |