6WMU
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![BU of 6wmu by Molmil](/molmil-images/mine/6wmu) | E. coli RNAPs70-SspA-gadA DNA complex | 分子名称: | DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ... | 著者 | Travis, B.A, Brennan, R.G, Schumacher, M.A. | 登録日 | 2020-04-21 | 公開日 | 2020-11-11 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Structural Basis for Virulence Activation of Francisella tularensis. Mol.Cell, 81, 2021
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8EG7
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![BU of 8eg7 by Molmil](/molmil-images/mine/8eg7) | Cryo-EM structure of pre-consensus elemental paused elongation complex | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-11 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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7MKD
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![BU of 7mkd by Molmil](/molmil-images/mine/7mkd) | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | 登録日 | 2021-04-23 | 公開日 | 2021-09-29 | 最終更新日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
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6X6T
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![BU of 6x6t by Molmil](/molmil-images/mine/6x6t) | Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B1 (TTC-B1) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | 登録日 | 2020-05-29 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
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6XLM
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![BU of 6xlm by Molmil](/molmil-images/mine/6xlm) | Cryo-EM structure of E.coli RNAP-DNA elongation complex 1 (RDe1) in EcmrR-dependent transcription | 分子名称: | 9-nt RNA transcript, CHAPSO, DNA-directed RNA polymerase subunit alpha, ... | 著者 | Yang, Y, Liu, C, Liu, B. | 登録日 | 2020-06-28 | 公開日 | 2021-04-07 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
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8PIL
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![BU of 8pil by Molmil](/molmil-images/mine/8pil) | E. coli transcription complex paused at ops site and bound to RfaH and NusA | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | 登録日 | 2023-06-22 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8UQL
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![BU of 8uql by Molmil](/molmil-images/mine/8uql) | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH in loaded state, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2023-10-24 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome Nat.Struct.Mol.Biol., 2024
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8U3B
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![BU of 8u3b by Molmil](/molmil-images/mine/8u3b) | Cryo-EM structure of E. coli NarL-transcription activation complex at 3.2A | 分子名称: | DNA (69-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Liu, B, Kompaniiets, D, Wang, D. | 登録日 | 2023-09-07 | 公開日 | 2024-01-17 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Structural basis for transcription activation by the nitrate-responsive regulator NarL. Nucleic Acids Res., 52, 2024
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3N97
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![BU of 3n97 by Molmil](/molmil-images/mine/3n97) | RNA polymerase alpha C-terminal domain (E. coli) and sigma region 4 (T. aq. mutant) bound to (UP,-35 element) DNA | 分子名称: | ACETATE ION, DNA (5'-D(*CP*CP*AP*TP*GP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP*TP*TP*TP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*AP*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*CP*AP*TP*GP*G)-3'), ... | 著者 | Lara-Gonzalez, S, Birktoft, J.J, Lawson, C.L. | 登録日 | 2010-05-28 | 公開日 | 2011-06-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.252 Å) | 主引用文献 | The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element. Biochemistry, 59, 2020
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6N61
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![BU of 6n61 by Molmil](/molmil-images/mine/6n61) | Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Capistruin | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Capistruin, ... | 著者 | Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-24 | 公開日 | 2019-01-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.253 Å) | 主引用文献 | Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6OMF
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![BU of 6omf by Molmil](/molmil-images/mine/6omf) | CryoEM structure of SigmaS-transcription initiation complex with activator Crl | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Jaramillo Cartagena, A, Darst, S.A, Campbell, E.A. | 登録日 | 2019-04-18 | 公開日 | 2019-08-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Structural basis for transcription activation by Crl through tethering of sigmaSand RNA polymerase. Proc.Natl.Acad.Sci.USA, 116, 2019
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8SY6
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![BU of 8sy6 by Molmil](/molmil-images/mine/8sy6) | E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-UTP base pair in the active site | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Shan, Z, Lyumkis, D, Oh, J, Wang, D. | 登録日 | 2023-05-24 | 公開日 | 2023-12-27 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase. Nat Commun, 14, 2023
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6X50
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![BU of 6x50 by Molmil](/molmil-images/mine/6x50) | Mfd-bound E.coli RNA polymerase elongation complex - V state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Llewelyn, E, Chen, J, Kang, J.Y, Darst, S.A. | 登録日 | 2020-05-24 | 公開日 | 2021-02-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase. Elife, 10, 2021
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7MKN
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![BU of 7mkn by Molmil](/molmil-images/mine/7mkn) | Escherichia coli RNA polymerase and RapA elongation complex | 分子名称: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Qayyum, M.Z, Murakami, K.S. | 登録日 | 2021-04-26 | 公開日 | 2021-06-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli. J.Biol.Chem., 297, 2021
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8EHF
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![BU of 8ehf by Molmil](/molmil-images/mine/8ehf) | Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (1) | 分子名称: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-14 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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8EG8
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![BU of 8eg8 by Molmil](/molmil-images/mine/8eg8) | Cryo-EM structure of consensus elemental paused elongation complex with a folded TL | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-12 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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6ZTM
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![BU of 6ztm by Molmil](/molmil-images/mine/6ztm) | E. coli 70S-RNAP expressome complex in collided state without NusG | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Webster, M.W, Takacs, M, Weixlbaumer, A. | 登録日 | 2020-07-20 | 公開日 | 2020-09-16 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
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7UBN
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5UAG
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![BU of 5uag by Molmil](/molmil-images/mine/5uag) | Escherichia coli RNA polymerase mutant - RpoB D516V | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Molodtsov, V, Scharf, N.T, Stefan, M.A, Garcia, G.A, Murakami, K.S. | 登録日 | 2016-12-19 | 公開日 | 2017-02-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.399 Å) | 主引用文献 | Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis. Mol. Microbiol., 103, 2017
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8EH8
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![BU of 8eh8 by Molmil](/molmil-images/mine/8eh8) | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (1) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-13 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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7M8E
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![BU of 7m8e by Molmil](/molmil-images/mine/7m8e) | E.coli RNAP-RapA elongation complex | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Shi, W, Liu, B. | 登録日 | 2021-03-29 | 公開日 | 2021-08-18 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for activation of Swi2/Snf2 ATPase RapA by RNA polymerase. Nucleic Acids Res., 49, 2021
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6RIP
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![BU of 6rip by Molmil](/molmil-images/mine/6rip) | Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex in swiveled state | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A. | 登録日 | 2019-04-24 | 公開日 | 2019-07-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation. Mol.Cell, 75, 2019
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6OUL
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![BU of 6oul by Molmil](/molmil-images/mine/6oul) | Cryo-EM structure of Escherichia coli RNAP polymerase bound to rpsTP2 promoter DNA | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | 登録日 | 2019-05-04 | 公開日 | 2020-02-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
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8PFJ
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![BU of 8pfj by Molmil](/molmil-images/mine/8pfj) | fully recruited RfaH bound to E. coli transcription complex paused at ops site (not fully complementary scaffold; alternative state of RfaH) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | 登録日 | 2023-06-16 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8PIM
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![BU of 8pim by Molmil](/molmil-images/mine/8pim) | fully recruited RfaH bound to E. coli transcription complex paused at ops site (not complementary scaffold) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | 登録日 | 2023-06-22 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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