4XOA
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![BU of 4xoa by Molmil](/molmil-images/mine/4xoa) | Crystal structure of a FimH*DsG complex from E.coli K12 in space group P1 | 分子名称: | FimG, Protein FimH | 著者 | Jakob, R.P, Eras, J, Glockshuber, R, Maier, T. | 登録日 | 2015-01-16 | 公開日 | 2016-01-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.541 Å) | 主引用文献 | Catch-bond mechanism of the bacterial adhesin FimH. Nat Commun, 7, 2016
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5MUC
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![BU of 5muc by Molmil](/molmil-images/mine/5muc) | Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol | 分子名称: | 1-deoxy-alpha-D-mannopyranose, Protein FimH | 著者 | Jakob, R.P, Rabbani, S, Ernst, B, Maier, T. | 登録日 | 2017-01-13 | 公開日 | 2018-02-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | KinITC-One Method Supports both Thermodynamic and Kinetic SARs as Exemplified on FimH Antagonists. Chemistry, 24, 2018
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5MTS
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![BU of 5mts by Molmil](/molmil-images/mine/5mts) | Complex of FimH lectin with a TazMan (thiazolylaminomannosides) family member known as potent anti-adhesive agent at 2.6 A resolution | 分子名称: | NICKEL (II) ION, Protein FimH, [2-[[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]amino]-1,3-thiazol-5-yl]-(4-methyl-2-pyrazin-2-yl-1,3-thiazol-5-yl)methanone | 著者 | de Ruyck, J, Bouckaert, J. | 登録日 | 2017-01-10 | 公開日 | 2017-03-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Physiochemical Tuning of Potent Escherichia coli Anti-Adhesives by Microencapsulation and Methylene Homologation. ChemMedChem, 12, 2017
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1KLF
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![BU of 1klf by Molmil](/molmil-images/mine/1klf) | |
7SZO
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![BU of 7szo by Molmil](/molmil-images/mine/7szo) | Structure of a bacterial fimbrial tip containing FocH | 分子名称: | Chaperone protein FimC, FimF protein, FimG, ... | 著者 | Stenkamp, R.E, Le Trong, I, Aprikian, P, Sokurenko, E.V. | 登録日 | 2021-11-29 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Recombinant FimH Adhesin Demonstrates How the Allosteric Catch Bond Mechanism Can Support Fast and Strong Bacterial Attachment in the Absence of Shear. J.Mol.Biol., 434, 2022
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3RFZ
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![BU of 3rfz by Molmil](/molmil-images/mine/3rfz) | Crystal structure of the FimD usher bound to its cognate FimC:FimH substrate | 分子名称: | Chaperone protein fimC, Outer membrane usher protein, type 1 fimbrial synthesis, ... | 著者 | Phan, G, Remaut, H, Lebedev, A, Geibel, S, Waksman, G. | 登録日 | 2011-04-07 | 公開日 | 2011-06-01 | 最終更新日 | 2012-03-28 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature, 474, 2011
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1QUN
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![BU of 1qun by Molmil](/molmil-images/mine/1qun) | X-RAY STRUCTURE OF THE FIMC-FIMH CHAPERONE ADHESIN COMPLEX FROM UROPATHOGENIC E.COLI | 分子名称: | MANNOSE-SPECIFIC ADHESIN FIMH, PAPD-LIKE CHAPERONE FIMC | 著者 | Choudhury, D, Thompson, A, Stojanoff, V, Langerman, S, Pinkner, J, Hultgren, S.J, Knight, S. | 登録日 | 1999-07-01 | 公開日 | 1999-08-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coli. Science, 285, 1999
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5L4V
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![BU of 5l4v by Molmil](/molmil-images/mine/5l4v) | Crystal structure of FimH lectin domain in complex with 3-Deoxy-Heptylmannoside | 分子名称: | Protein FimH, heptyl 3-deoxy-alpha-D-mannopyranoside | 著者 | Jakob, R.P, Zihlmann, P, Rabbani, S, Maier, T, Ernst, T. | 登録日 | 2016-05-26 | 公開日 | 2017-06-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | High-Affinity Carbohydrate-Lectin Interactions: How Nature Makes it Possible To Be Published
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8BVD
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![BU of 8bvd by Molmil](/molmil-images/mine/8bvd) | FimH lectin domain in complex with mannose C-linked to quinoline | 分子名称: | (2R,3S,4R,5S,6R)-2-(hydroxymethyl)-6-[(E)-3-quinolin-6-ylprop-2-enyl]oxane-3,4,5-triol, Type 1 fimbrin D-mannose specific adhesin | 著者 | Bouckaert, J, Bridot, C. | 登録日 | 2022-12-03 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-08 | 実験手法 | X-RAY DIFFRACTION (2.995 Å) | 主引用文献 | Insightful Improvement in the Design of Potent Uropathogenic E. coli FimH Antagonists. Pharmaceutics, 15, 2023
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7QUO
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![BU of 7quo by Molmil](/molmil-images/mine/7quo) | |
1KIU
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![BU of 1kiu by Molmil](/molmil-images/mine/1kiu) | |
4XOB
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![BU of 4xob by Molmil](/molmil-images/mine/4xob) | Crystal structure of a FimH*DsF complex from E.coli K12 with bound heptyl alpha-D-mannopyrannoside | 分子名称: | FimF, Protein FimH, SULFATE ION, ... | 著者 | Jakob, R.P, Eras, J, Navarra, G, Ernst, B, Glockshuber, R, Maier, T. | 登録日 | 2015-01-16 | 公開日 | 2016-01-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.003 Å) | 主引用文献 | Catch-bond mechanism of the bacterial adhesin FimH. Nat Commun, 7, 2016
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8BY3
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![BU of 8by3 by Molmil](/molmil-images/mine/8by3) | FimH lectin domain in complex with oligomannose-6 | 分子名称: | NICKEL (II) ION, SULFATE ION, Type 1 fimbrin D-mannose specific adhesin, ... | 著者 | Bouckaert, J, Bourenkov, G.P. | 登録日 | 2022-12-11 | 公開日 | 2023-04-12 | 最終更新日 | 2023-04-26 | 実験手法 | X-RAY DIFFRACTION (3.186 Å) | 主引用文献 | Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors. J.Biol.Chem., 299, 2023
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4J3O
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![BU of 4j3o by Molmil](/molmil-images/mine/4j3o) | |
6E14
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![BU of 6e14 by Molmil](/molmil-images/mine/6e14) | Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD | 分子名称: | Chaperone protein FimC, Fimbrial biogenesis outer membrane usher protein, Protein FimF, ... | 著者 | Du, M, Yuan, Z, Yu, H, Henderson, N, Sarowar, S, Zhao, G, Werneburg, G.T, Thanassi, D.G, Li, H. | 登録日 | 2018-07-09 | 公開日 | 2018-10-17 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD. Nature, 562, 2018
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6E15
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![BU of 6e15 by Molmil](/molmil-images/mine/6e15) | Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD | 分子名称: | Chaperone protein FimC, Fimbrial biogenesis outer membrane usher protein, Protein FimF, ... | 著者 | Du, M, Yuan, Z, Yu, H, Henderson, N, Sarowar, S, Zhao, G, Werneburg, G.T, Thanassi, D.G, Li, H. | 登録日 | 2018-07-09 | 公開日 | 2018-10-17 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD. Nature, 562, 2018
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