5MUC

Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol

Summary for 5MUC

• Entry DOI: 10.2210/pdb5muc/pdb
• Descriptor: Protein FimH, 1-deoxy-alpha-D-mannopyranose (3 entities in total)
• Functional Keywords: fimh, uti, lectin, carbohydrate, upec, bladder infection, sugar binding protein
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 2
• Total formula weight: 34161.97

Authors

Jakob, R.P.,Rabbani, S.,Ernst, B.,Maier, T. (deposition date: 2017-01-13, release date: 2018-02-14, Last modification date: 2024-01-17)

• Primary citation: Zihlmann, P.,Silbermann, M.,Sharpe, T.,Jiang, X.,Muhlethaler, T.,Jakob, R.P.,Rabbani, S.,Sager, C.P.,Frei, P.,Pang, L.,Maier, T.,Ernst, B.; KinITC-One Method Supports both Thermodynamic and Kinetic SARs as Exemplified on FimH Antagonists.; Chemistry, 24:13049-13057, 2018; PubMed: 29939458; DOI: 10.1002/chem.201802599

Experimental method

X-RAY DIFFRACTION (2.6 Å)