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PDB: 15 件
1LF7
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Crystal Structure of Human Complement Protein C8gamma at 1.2 A Resolution
分子名称: CITRIC ACID, Complement Protein C8gamma
著者Ortlund, E, Parker, C.L, Schreck, S.F, Ginell, S, Minor, W, Sodetz, J.M, Lebioda, L.
登録日2002-04-10
公開日2002-06-12
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site.
Biochemistry, 41, 2002
2OVA
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BU of 2ova by Molmil
X-ray structure of Human Complement Protein C8gamma Y83W Mutant
分子名称: Complement component 8, gamma polypeptide
著者Chiswell, B, Lovelace, L.L, Brannen, C, Ortlund, E.A, Lebioda, L, Sodetz, J.M.
登録日2007-02-13
公開日2007-05-22
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural features of the ligand binding site on human complement protein C8gamma: A member of the lipocalin family
Biochim.Biophys.Acta, 1774, 2007
2OVD
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Crystal Structure of Human Complement Protein C8gamma with Laurate
分子名称: Complement component 8, gamma polypeptide, LAURIC ACID
著者Chiswell, B, Lovelace, L.L, Brannen, C, Ortlund, E.A, Lebioda, L, Sodetz, J.M.
登録日2007-02-13
公開日2007-05-22
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural features of the ligand binding site on human complement protein C8gamma: A member of the lipocalin family
Biochim.Biophys.Acta, 1774, 2007
2QOS
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BU of 2qos by Molmil
Crystal structure of complement protein C8 in complex with a peptide containing the C8 binding site on C8
分子名称: Complement component 8, gamma polypeptide, Complement component C8 alpha chain
著者Lovelace, L.L, Chiswell, B, Slade, D.J, Sodetz, J.M, Lebioda, L.
登録日2007-07-20
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: Implications for C8gamma ligand binding.
Mol.Immunol., 45, 2008
1IW2
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BU of 1iw2 by Molmil
X-ray structure of Human Complement Protein C8gamma at pH=7.O
分子名称: Complement Protein C8gamma
著者Ortlund, E, Parker, C.L, Schreck, S.F, Ginell, S, Minor, W, Sodetz, J.M, Lebioda, L.
登録日2002-04-11
公開日2002-06-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site.
Biochemistry, 41, 2002
2OVE
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BU of 2ove by Molmil
Crystal Structure of Recombinant Human Complement Protein C8gamma
分子名称: Complement component 8, gamma polypeptide
著者Chiswell, B, Lovelace, L.L, Brannen, C, Ortlund, E.A, Lebioda, L, Sodetz, J.M.
登録日2007-02-13
公開日2007-05-22
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural features of the ligand binding site on human complement protein C8gamma: A member of the lipocalin family
Biochim.Biophys.Acta, 1774, 2007
2RD7
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BU of 2rd7 by Molmil
Human Complement Membrane Attack Proteins Share a Common Fold with Bacterial Cytolysins
分子名称: CHLORIDE ION, Complement component C8 alpha chain, Complement component C8 gamma chain
著者Slade, D.J, Lovelace, L.L, Chruszcz, M, Minor, W, Lebioda, L, Sodetz, J.M.
登録日2007-09-21
公開日2008-05-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J. Biol. Chem., 286, 2011
3OJY
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BU of 3ojy by Molmil
Crystal Structure of Human Complement Component C8
分子名称: CALCIUM ION, Complement component C8 alpha chain, Complement component C8 beta chain, ...
著者Lovelace, L.L, Cooper, C.L, Sodetz, J.M, Lebioda, L.
登録日2010-08-23
公開日2011-04-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J.Biol.Chem., 286, 2011
8B0F
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CryoEM structure of C5b8-CD59
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Bubeck, D, Couves, E.C, Gardner, S.
登録日2022-09-07
公開日2023-02-22
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
8B0H
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BU of 8b0h by Molmil
2C9, C5b9-CD59 cryoEM structure
分子名称: CD59 glycoprotein, Complement C5, Complement component C6, ...
著者Couves, E.C, Gardner, S, Bubeck, D.
登録日2022-09-07
公開日2023-02-22
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
7NYD
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cryoEM structure of 2C9-sMAC
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Menny, A, Couves, E.C, Bubeck, D.
登録日2021-03-22
公開日2021-10-06
最終更新日2021-11-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of soluble membrane attack complex packaging for clearance.
Nat Commun, 12, 2021
8B0G
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BU of 8b0g by Molmil
2C9, C5b9-CD59 structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD59 glycoprotein, Complement C5, ...
著者Couves, E.C, Gardner, S, Bubeck, D.
登録日2022-09-07
公開日2023-02-22
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
7NYC
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BU of 7nyc by Molmil
cryoEM structure of 3C9-sMAC
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Menny, A, Couves, E.C, Bubeck, D.
登録日2021-03-22
公開日2021-10-06
最終更新日2021-11-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of soluble membrane attack complex packaging for clearance.
Nat Commun, 12, 2021
6H03
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BU of 6h03 by Molmil
OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ...
著者Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D.
登録日2018-07-06
公開日2018-12-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
6H04
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BU of 6h04 by Molmil
Closed conformation of the Membrane Attack Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ...
著者Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D.
登録日2018-07-06
公開日2018-12-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018

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