5YB3
 
 | | Crystal structure of HP23L/N36 | | 分子名称: | Envelope glycoprotein, HP23L | | 著者 | Zhang, X, Wang, X, He, Y. | | 登録日 | 2017-09-03 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.043 Å) | | 主引用文献 | Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket
Front Cell Infect Microbiol, 8, 2018
|
|
3D0V
 | | Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide LLELDKWASLW | | 分子名称: | 2F5 Fab heavy chain, 2F5 Fab light chain, gp41 peptide LLELDKWASLW | | 著者 | Bryson, S, Julien, J.P, Pai, E.F. | | 登録日 | 2008-05-02 | | 公開日 | 2008-07-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site.
J.Mol.Biol., 384, 2008
|
|
8G8C
 | | Crystal structure of DH1322.1 Fab in complex with HIV proximal MPER peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1322.1 heavy chain, DH1322.1 light chain, ... | | 著者 | Niyongabo, A, Janus, B.M, Ofek, G. | | 登録日 | 2023-02-17 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 187, 2024
|
|
5IVX
 | | Crystal Structure of B4.2.3 T-Cell Receptor and H2-Dd P18-I10 Complex | | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | | 著者 | Natarajan, K, Jiang, J, Margulies, D. | | 登録日 | 2016-03-21 | | 公開日 | 2017-03-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | An allosteric site in the T-cell receptor C beta domain plays a critical signalling role.
Nat Commun, 8, 2017
|
|
6P8D
 | |
5CMU
 | |
5TKJ
 | | Structure of vaccine-elicited diverse HIV-1 neutralizing antibody vFP1.01 in complex with HIV-1 fusion peptide residue 512-519 | | 分子名称: | HIV-1 fusion peptide residue 512-519, SULFATE ION, vFP1.01 chimeric mouse antibody heavy chain, ... | | 著者 | Xu, K, Liu, K, Kwong, P.D. | | 登録日 | 2016-10-06 | | 公開日 | 2018-04-04 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.118 Å) | | 主引用文献 | Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
|
|
1RZJ
 | | HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... | | 著者 | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | | 登録日 | 2003-12-24 | | 公開日 | 2004-02-03 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
2ZZO
 | | Crystal structure of the complex between GP41 fragment N36 and fusion inhibitor C34/S138A | | 分子名称: | Transmembrane protein | | 著者 | Watabe, T, Nakano, H, Nakatsu, T, Kato, H, Fujii, N. | | 登録日 | 2009-02-20 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | X-ray crystallographic study of an HIV-1 fusion inhibitor with the gp41 S138A substitution
J.Mol.Biol., 392, 2009
|
|
3MNW
 | | Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment with a gp41 MPER-derived peptide in a helical conformation | | 分子名称: | 1,2-ETHANEDIOL, ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN, ... | | 著者 | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | | 登録日 | 2010-04-22 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of a Non-Neutralizing HIV-1 gp41 Envelope Antibody Demonstrates Neutralization Mechanism of gp41 Antibodies
To be Published
|
|
1G9M
 | | HIV-1 HXBC2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... | | 著者 | Kwong, P.D, Wyatt, R, Majeed, S, Robinson, J, Sweet, R.W, Sodroski, J, Hendrickson, W.A. | | 登録日 | 2000-11-24 | | 公開日 | 2000-12-27 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Structure Fold.Des., 8, 2000
|
|
5HFL
 | |
5HFM
 | |
5ZCX
 | | Structure of T20/N39 | | 分子名称: | Envelope glycoprotein, Envelope glycoprotein gp160 | | 著者 | Zhang, X.J, Ding, X.H. | | 登録日 | 2018-02-21 | | 公開日 | 2018-10-10 | | 最終更新日 | 2018-12-19 | | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | | 主引用文献 | Structural and functional characterization of HIV-1 cell fusion inhibitor T20.
AIDS, 33, 2019
|
|
2XRA
 | | crystal structure of the HK20 Fab in complex with a gp41 mimetic 5- Helix | | 分子名称: | HK20, HUMAN MONOCLONAL ANTIBODY HEAVY CHAIN, HUMAN MONOCLONAL ANTIBODY LIGHT CHAIN, ... | | 著者 | Sabin, C, Corti, D, Buzon, V, Seaman, M.S, Lutje Hulsik, D, Hinz, A, Vanzetta, F, Agatic, G, Silacci, C, Langedijk, J.P.M, Mainetti, L, Scarlatti, G, Sallusto, F, Weiss, R, Lanzavecchia, A, Weissenhorn, W. | | 登録日 | 2010-09-13 | | 公開日 | 2010-12-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41.
PLoS Pathog., 6, 2010
|
|
4ZTO
 | |
2NY7
 | | HIV-1 gp120 Envelope Glycoprotein Complexed with the Broadly Neutralizing CD4-Binding-Site Antibody b12 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY b12, HEAVY CHAIN, ... | | 著者 | Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D. | | 登録日 | 2006-11-20 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
|
|
6N16
 | |
6J5E
 | |
6NPR
 | | Crystal structure of H-2Dd with C84-C139 disulfide in complex with gp120 derived peptide P18-I10 | | 分子名称: | ARG-GLY-PRO-GLY-ARG-ALA-PHE-VAL-THR-ILE, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | | 著者 | Toor, J, McShan, A.C, Tripathi, S.M, Sgourakis, N.G. | | 登録日 | 2019-01-18 | | 公開日 | 2020-01-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
4JPK
 | | Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain eOD-GT6 in complex with a putative VRC01 germline precursor Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6, ... | | 著者 | Julien, J.-P, Jardine, J, Schief, W.R, Wilson, I.A. | | 登録日 | 2013-03-19 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Rational HIV immunogen design to target specific germline B cell receptors.
Science, 340, 2013
|
|
5GHW
 | | Crystal structure of broad neutralizing antibody 10E8 with long epitope bound | | 分子名称: | Endogenous retrovirus group K member 8 Env polyprotein, FAB 10E8 HEAVY CHAIN, FAB 10E8 LIGHT CHAIN, ... | | 著者 | Caaveiro, J.M.M, Rujas, E, Morante, K, Nieva, J.L, Tsumoto, K. | | 登録日 | 2016-06-21 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface
Sci Rep, 6, 2016
|
|
8G8A
 | | Crystal structure of DH1317.8 Fab in complex with HIV proximal MPER peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1317.8 heavy chain, DH1317.8 light chain, ... | | 著者 | Janus, B.M, Astavans, A, Ofek, G. | | 登録日 | 2023-02-17 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 187, 2024
|
|
8FYM
 | | Crystal structure of Fab235 in complex with MPER peptide | | 分子名称: | ALA-SER-LEU-TRP-ASN-TRP-PHE-ASN-ILE-THR-ASN-TRP-LEU-TRP-TYR-ILE-LYS-LYS-LYS, CHLORIDE ION, Fab235, ... | | 著者 | Tan, K, Kim, M, Reinherz, E.L. | | 登録日 | 2023-01-26 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.
Nat Commun, 14, 2023
|
|
6MQR
 | | Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-a.01 in complex with FP (residue 512-519) | | 分子名称: | CALCIUM ION, HIV fusion peptide residue 512-519, SULFATE ION, ... | | 著者 | Xu, K, Wang, Y, Kwong, P.D. | | 登録日 | 2018-10-10 | | 公開日 | 2019-07-31 | | 最終更新日 | 2019-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
|
|
