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PDB: 354 件
3W7Y
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0.92A structure of 2Zn human insulin at 100K
分子名称: Insulin, ZINC ION
著者Sakabe, N, Sakabe, K, Sasaki, K, Murayoshi, M.
登録日2013-03-11
公開日2013-07-03
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (0.92 Å)
主引用文献0.92A structure of 2Zn human insulin at 100K
To be Published
5E7W
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X-ray Structure of Human Recombinant 2Zn insulin at 0.92 Angstrom
分子名称: ACETATE ION, Insulin, N-PROPANOL, ...
著者Lisgarten, D.R, Naylor, C.E, Palmer, R.A, Lobley, C.M.C.
登録日2015-10-13
公開日2016-10-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (0.9519 Å)
主引用文献Ultra-high resolution X-ray structures of two forms of human recombinant insulin at 100 K.
Chem Cent J, 11, 2017
5HQI
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Insulin with proline analog HzP at position B28 in the T2 state
分子名称: Insulin A-Chain, Insulin B-Chain
著者Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A.
登録日2016-01-21
公開日2017-01-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (0.97 Å)
主引用文献4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation.
J. Am. Chem. Soc., 139, 2017
3HYD
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LVEALYL peptide derived from human insulin chain B, residues 11-17
分子名称: Insulin
著者Ivanova, M.I, Sawaya, M.R, Eisenberg, D.
登録日2009-06-22
公開日2009-10-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Molecular basis for insulin fibril assembly.
Proc.Natl.Acad.Sci.USA, 106, 2009
1MSO
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BU of 1mso by Molmil
T6 Human Insulin at 1.0 A Resolution
分子名称: Insulin A-Chain, Insulin B-Chain, ZINC ION
著者Smith, G.D, Pangborn, W.A, Blessing, R.H.
登録日2002-09-19
公開日2003-03-04
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献The structure of T6 human insulin at 1.0 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
6VER
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Human insulin analog: [GluB10,TyrB20]-DOI
分子名称: Insulin A chain, Insulin B chain
著者Menting, J.G, Chou, D.H.-C, Lawrence, M.C, Xiong, X.
登録日2020-01-02
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.047 Å)
主引用文献Mini-Ins: A minimal, bioactive insulin analog with alternative binding modes
not published
4FKA
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High resolution structure of the manganese derivative of insulin
分子名称: Insulin A chain, Insulin B chain, MANGANESE (II) ION, ...
著者Prugovecki, B, Pulic, I, Toth, M, Matkovic-Calogovic, D.
登録日2012-06-13
公開日2013-02-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献High Resolution Structure of the Manganese Derivative of Insulin
Croat.Chem.Acta, 85, 2012
3TT8
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Crystal Structure Analysis of Cu Human Insulin Derivative
分子名称: COPPER (II) ION, INSULIN A-CHAIN, INSULIN B-CHAIN
著者Prugovecki, B, Matkovic-Calogovic, D.
登録日2011-09-14
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Crystal Structure Analysis of Cu Human Insulin Derivative
To be Published
3W7Z
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1.15A structure of human 2Zn insulin at 293K
分子名称: Insulin, ZINC ION
著者Hoshikawa, N, Sasaki, K, Sakabe, N, Sakabe, K.
登録日2013-03-11
公開日2013-07-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献1.15A structure of human 2Zn insulin at 293K
To be Published
8OKY
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Crystal structure of D-ProB26-DTriA analogue of human insulin
分子名称: Insulin A chain, Insulin B chain
著者Brzozowski, A.M, Zakova, L, Jiracek, J.
登録日2023-03-29
公開日2024-04-10
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Analogues of human insulin with specificity to insulin receptor isoform B
To Be Published
5USP
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Insulin with proline analog Pip at position B28 in the T2 state
分子名称: Insulin Chain A, Insulin Chain B, SODIUM ION
著者Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
登録日2017-02-13
公開日2018-02-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.174 Å)
主引用文献Insulin with proline analog Pip at position B28 in the T2 state
To Be Published
5UOZ
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Insulin with proline analog FyP at position B28 in the T2 state
分子名称: Insulin Chain A, Insulin Chain B
著者Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
登録日2017-02-01
公開日2018-02-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.17463875 Å)
主引用文献Insulin with proline analog FyP at position B28 in the T2 state
To Be Published
5URT
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Insulin with proline analog DhP at position B28 in the T2 state
分子名称: Insulin Chain A, Insulin Chain B, SODIUM ION
著者Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
登録日2017-02-12
公開日2018-02-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Insulin with proline analog DhP at position B28 in the T2 state
To Be Published
4AJX
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Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
分子名称: IMIDAZOLE, INSULIN, N-(16-Carboxyhexadecanoyl)-L-glutamic acid, ...
著者Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
登録日2012-02-20
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
1G7A
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1.2 A structure of T3R3 human insulin at 100 K
分子名称: ACETONE, CHLORIDE ION, GLYCEROL, ...
著者Smith, G.D, Pangborn, W.A, Blessing, R.H.
登録日2000-11-09
公開日2001-08-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Phase changes in T(3)R(3)(f) human insulin: temperature or pressure induced?
Acta Crystallogr.,Sect.D, 57, 2001
7QGF
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Cubic Insulin SAD phasing at 14.2 keV
分子名称: Insulin A chain, Insulin B chain
著者Nanao, M.H, Basu, S.
登録日2021-12-08
公開日2022-06-01
実験手法X-RAY DIFFRACTION (1.203 Å)
主引用文献ID23-2: an automated and high-performance microfocus beamline for macromolecular crystallography at the ESRF.
J.Synchrotron Radiat., 29, 2022
5UU2
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Insulin with proline analog ThioP at position B28 in the T2 state
分子名称: Insulin Chain A, Insulin Chain B
著者Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
登録日2017-02-15
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.223 Å)
主引用文献Insulin with proline analog ThioP at position B28 in the T2 state
To Be Published
7RKD
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BU of 7rkd by Molmil
X-Ray structure of Insulin Analog GLULISINE
分子名称: Insulin B chain analog, Insulin chain A, ZINC ION
著者Reyes-Grajeda, J.P.
登録日2021-07-22
公開日2022-07-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Insulin ANALOGS
To Be Published
8PI4
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BU of 8pi4 by Molmil
Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in dimer (T2) conformation
分子名称: Insulin B chain,Insulin A chain
著者Johansson, E, Schluckebier, G.
登録日2023-06-21
公開日2023-11-08
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 42, 2024
6GV0
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BU of 6gv0 by Molmil
Insulin glulisine
分子名称: FORMIC ACID, Insulin, ZINC ION
著者Chayen, N.E, Helliwell, J.R, Solomon-Gamsu, H.V, Govada, L, Morgan, M, Gillis, R.B, Adams, G.
登録日2018-06-20
公開日2019-07-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques.
Sci Rep, 11, 2021
5HRQ
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BU of 5hrq by Molmil
Insulin with proline analog HzP at position B28 in the R6 state
分子名称: CHLORIDE ION, Insulin A-Chain, Insulin B-Chain, ...
著者Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A.
登録日2016-01-24
公開日2017-01-25
最終更新日2020-01-15
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation.
J. Am. Chem. Soc., 139, 2017
3BXQ
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The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition
分子名称: ZINC ION, insulin A chain, insulin B chain
著者Wan, Z.L, Huang, K, Hu, S.Q, Whittaker, J, Weiss, M.A.
登録日2008-01-14
公開日2008-05-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition.
J.Biol.Chem., 283, 2008
5USV
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Insulin with proline analog AzeP at position B28 in the T2 state
分子名称: Insulin Chain A, Insulin Chain B, SODIUM ION
著者Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
登録日2017-02-14
公開日2018-02-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Insulin with proline analog AzeP at position B28 in the T2 state
To Be Published
1G7B
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1.3 A STRUCTURE OF T3R3 HUMAN INSULIN AT 100 K
分子名称: ACETONE, CHLORIDE ION, GLYCEROL, ...
著者Smith, G.D, Pangborn, W.A, Blessing, R.H.
登録日2000-11-09
公開日2001-08-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Phase changes in T(3)R(3)(f) human insulin: temperature or pressure induced?
Acta Crystallogr.,Sect.D, 57, 2001
5UQA
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Insulin with proline analog FzP at position B28 in the R6 state
分子名称: ACETONE, CHLORIDE ION, GLYCEROL, ...
著者Lieblich, S.A, Fang, K.Y, Tirrell, D.A.
登録日2017-02-07
公開日2018-02-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.31000245 Å)
主引用文献Insulin with proline analog FzP at position B28 in the R6 state
To Be Published

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