2DE8
 
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1L0Z
 | | THE STRUCTURE OF PORCINE PANCREATIC ELASTASE COMPLEXED WITH XENON AND BROMIDE, CRYOPROTECTED WITH DRY PARAFFIN OIL | | 分子名称: | BROMIDE ION, ELASTASE 1, SODIUM ION, ... | | 著者 | Tucker, P.A, Panjikar, S. | | 登録日 | 2002-02-14 | | 公開日 | 2002-08-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Xenon derivatization of halide-soaked protein crystals.
Acta Crystallogr.,Sect.D, 58, 2002
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1L1G
 | | The Structure of Porcine Pancreatic Elastase Complexed with Xenon and Bromide, Cryoprotected with Glycerol | | 分子名称: | BROMIDE ION, ELASTASE 1, GLYCEROL, ... | | 著者 | Panjikar, S, Tucker, P.A. | | 登録日 | 2002-02-16 | | 公開日 | 2002-08-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Xenon derivatization of halide-soaked protein crystals.
Acta Crystallogr.,Sect.D, 58, 2002
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4GVU
 | | Lyngbyastatin 7-Porcine Pancreatic Elastase Co-crystal Structure | | 分子名称: | CALCIUM ION, Chymotrypsin-like elastase family member 1, Lyngbyastatin 7, ... | | 著者 | Salvador, L.A, Taori, K, Biggs, J.S, Jakoncic, J, Ostrov, D, Paul, V.J, Luesch, H. | | 登録日 | 2012-08-31 | | 公開日 | 2013-02-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Potent elastase inhibitors from cyanobacteria: structural basis and mechanisms mediating cytoprotective and anti-inflammatory effects in bronchial epithelial cells.
J.Med.Chem., 56, 2013
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3MU8
 | | Comparison of the character and the speed of X-ray-induced structural changes of porcine pancreatic elastase at two temperatures, 100 and 15K. The data set was collected from region B of the crystal. Fifth step of radiation damage | | 分子名称: | Chymotrypsin-like elastase family member 1, SODIUM ION, SULFATE ION | | 著者 | Petrova, T, Ginell, S, Mitschler, A, Cousido-Siah, A, Hazemann, I, Podjarny, A, Joachimiak, A. | | 登録日 | 2010-05-02 | | 公開日 | 2010-05-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.553 Å) | | 主引用文献 | X-ray-induced deterioration of disulfide bridges at atomic resolution.
Acta Crystallogr.,Sect.D, 66, 2010
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8B04
 | | STRUCTURE OF PORCINE PANCREATIC ELASTASE BOUND TO A FRAGMENT OF AN ISOXAZOLONE INHIBITOR | | 分子名称: | 2-cyclopropylcarbonyl-3-propan-2-yl-1,2-oxazol-5-one, CALCIUM ION, Chymotrypsin-like elastase family member 1, ... | | 著者 | Ferraroni, M, Giovannoni, P, Masini, V. | | 登録日 | 2022-09-07 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | X-ray structural study of human neutrophil elastase inhibition with a series of azaindoles, azaindazoles and isoxazolones
J.Mol.Struct., 1274, 2023
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1QR3
 | | Structure of porcine pancreatic elastase in complex with FR901277, a novel macrocyclic inhibitor of elastases at 1.6 angstrom resolution | | 分子名称: | CALCIUM ION, Chymotrypsin-like elastase family member 1, FR901277 Inhibitor, ... | | 著者 | Nakanishi, I, Kinoshita, T, Sato, A, Tada, T. | | 登録日 | 1999-06-18 | | 公開日 | 2000-06-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of porcine pancreatic elastase complexed with FR901277, a novel macrocyclic inhibitor of elastases, at 1.6 A resolution.
Biopolymers, 53, 2000
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1HAX
 | | Snapshots of serine protease catalysis: (A) acyl-enzyme intermediate between porcine pancreatic elastase and human beta-casomorphin-7 at pH 5 | | 分子名称: | BETA-CASOMORPHIN-7, CALCIUM ION, ELASTASE 1, ... | | 著者 | Wilmouth, R.C, Edman, K, Neutze, R, Wright, P.A, Clifton, I.J, Schneider, T.R, Schofield, C.J, Hajdu, J. | | 登録日 | 2001-04-10 | | 公開日 | 2001-08-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
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1BTU
 | | PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4R)-1-TOLUENESULPHONYL-3-ETHYL-AZETIDIN-2-ONE-4-CARBOXYLIC ACID | | 分子名称: | (3R)-3-ethyl-N-[(4-methylphenyl)sulfonyl]-L-aspartic acid, CALCIUM ION, ELASTASE, ... | | 著者 | Wilmouth, R.C, Clifton, I.J, Schofield, C.J. | | 登録日 | 1998-09-01 | | 公開日 | 1999-02-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex.
Biochemistry, 37, 1998
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2BD7
 | | Porcine pancreatic elastase complexed with beta-casomorphin-7 and Arg-Phe at pH 5.0 (50 min soak) | | 分子名称: | ARGININE, CALCIUM ION, Elastase-1, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2005-10-20 | | 公開日 | 2006-05-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
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2BD3
 | | Porcine pancreatic elastase complexed with beta-casomorphin-7 and Lys-Ala-NH2 at pH 5.0 | | 分子名称: | ALANINE, CALCIUM ION, Elastase-1, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2005-10-20 | | 公開日 | 2006-05-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
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2BB4
 | | Porcine pancreatic elastase complexed with beta-casomorphin-7 and Asp-Phe at pH 5.0 | | 分子名称: | ASPARTIC ACID, CALCIUM ION, Elastase-1, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2005-10-17 | | 公開日 | 2006-05-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
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2H1U
 | | Porcine pancreatic elastase complexed with MetPheLeuGlu at pH 5.0 | | 分子名称: | CALCIUM ION, Elastase-1, MFLE, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2006-05-17 | | 公開日 | 2006-05-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis.
J.Biol.Chem., 281, 2006
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3E3T
 | | Structure of porcine pancreatic elastase with the magic triangle I3C | | 分子名称: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Elastase-1, IODIDE ION, ... | | 著者 | Beck, T, Gruene, T, Sheldrick, G.M. | | 登録日 | 2008-08-08 | | 公開日 | 2008-10-28 | | 最終更新日 | 2012-04-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A magic triangle for experimental phasing of macromolecules
Acta Crystallogr.,Sect.D, 64, 2008
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2IOT
 | | Clavulanic Acid bound to Elastase | | 分子名称: | Elastase-1, N-(3-OXOPROPYL)GLYCINE, SULFATE ION | | 著者 | Farady, C, Navia, M.A. | | 登録日 | 2006-10-10 | | 公開日 | 2008-04-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Elastase Inhibition by Clavulanic Acid, and Inhibitor of Bacterial b-lactamases: Mechanistic and Structural Studies
To be Published
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3EST
 | | STRUCTURE OF NATIVE PORCINE PANCREATIC ELASTASE AT 1.65 ANGSTROMS RESOLUTION | | 分子名称: | CALCIUM ION, PORCINE PANCREATIC ELASTASE, SULFATE ION | | 著者 | Meyer, E.F, Cole, G, Radhakrishnan, R, Epp, O. | | 登録日 | 1987-09-17 | | 公開日 | 1988-01-16 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure of native porcine pancreatic elastase at 1.65 A resolutions.
Acta Crystallogr.,Sect.B, 44, 1988
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1ELG
 | | NATURE OF THE INACTIVATION OF ELASTASE BY N-PEPTIDYL-O-AROYL HYDROXYLAMINE AS A FUNCTION OF PH | | 分子名称: | (TERT-BUTYLOXYCARBONYL)-ALANYL-ALANYL-AMINE, CALCIUM ION, PORCINE PANCREATIC ELASTASE | | 著者 | Ding, X, Rasmussen, B, Demuth, H.-U, Ringe, D, Steinmetz, A.C.U. | | 登録日 | 1995-03-13 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Nature of the inactivation of elastase by N-peptidyl-O-aroyl hydroxylamine as a function of pH.
Biochemistry, 34, 1995
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2A7J
 | | On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection Wavelength | | 分子名称: | ACETATE ION, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Mueller-Dieckmann, C, Panjikar, S, Tucker, P.A, Weiss, M.S. | | 登録日 | 2005-07-05 | | 公開日 | 2005-07-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part III. The optimal data-collection wavelength.
Acta Crystallogr.,Sect.D, 61, 2005
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1ESA
 | | DIRECT STRUCTURE OBSERVATION OF AN ACYL-ENZYME INTERMEDIATE IN THE HYDROLYSIS OF AN ESTER SUBSTRATE BY ELASTASE | | 分子名称: | CALCIUM ION, PORCINE PANCREATIC ELASTASE, SULFATE ION | | 著者 | Ding, X, Rasmussen, B, Petsko, G.A, Ringe, D. | | 登録日 | 1994-02-04 | | 公開日 | 1994-04-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Direct structural observation of an acyl-enzyme intermediate in the hydrolysis of an ester substrate by elastase.
Biochemistry, 33, 1994
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1NES
 | | STRUCTURE OF THE PRODUCT COMPLEX OF ACETYL-ALA-PRO-ALA WITH PORCINE PANCREATIC ELASTASE AT 1.65 ANGSTROMS RESOLUTION | | 分子名称: | ACETYL-ALA-PRO-ALA, CALCIUM ION, ELASTASE, ... | | 著者 | Meyer Junior, E.F, Radhakrishnan, R, M Cole, G, Presta, L.G. | | 登録日 | 1995-07-31 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure of the product complex of acetyl-Ala-Pro-Ala with porcine pancreatic elastase at 1.65 A resolution.
J.Mol.Biol., 189, 1986
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1UO6
 | | PORCINE PANCREATIC ELASTASE/Xe-COMPLEX | | 分子名称: | CHLORIDE ION, ELASTASE 1, GLYCEROL, ... | | 著者 | Mueller-Dieckmann, C, Polentarutti, M, Djinovic-Carugo, K, Panjikar, S, Tucker, P.A, Weiss, M.S. | | 登録日 | 2003-09-16 | | 公開日 | 2003-10-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | On the Routine Use of Soft X-Rays in Macromolecular Crystallography. Part II. Data-Collection Wavelength and Scaling Models
Acta Crystallogr.,Sect.D, 60, 2004
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2A7C
 | | On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection Wavelength | | 分子名称: | Elastase 1, GLYCEROL, SULFATE ION, ... | | 著者 | Mueller-Dieckmann, C, Panjikar, S, Tucker, P.A, Weiss, M.S. | | 登録日 | 2005-07-05 | | 公開日 | 2005-07-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | On the routine use of soft X-rays in macromolecular crystallography. Part III. The optimal data-collection wavelength.
Acta Crystallogr.,Sect.D, 61, 2005
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2V0B
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3HGN
 | | Structure of porcine pancreatic elastase complexed with a potent peptidyl inhibitor FR130180 determined by neutron crystallography | | 分子名称: | 4-[[(2S)-3-methyl-1-oxo-1-[(2S)-2-[[(3S)-1,1,1-trifluoro-4-methyl-2-oxo-pentan-3-yl]carbamoyl]pyrrolidin-1-yl]butan-2-yl]carbamoyl]benzoic acid, CALCIUM ION, Elastase-1, ... | | 著者 | Tamada, T, Kinoshita, T, Kuroki, R, Tada, T. | | 登録日 | 2009-05-14 | | 公開日 | 2009-07-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | NEUTRON DIFFRACTION (1.65 Å), X-RAY DIFFRACTION | | 主引用文献 | Combined High-Resolution Neutron and X-ray Analysis of Inhibited Elastase Confirms the Active-Site Oxyanion Hole but Rules against a Low-Barrier Hydrogen Bond
J.Am.Chem.Soc., 131, 2009
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3MO6
 | | Investigation of global and local effects of radiation damage on porcine pancreatic elastase. Sixth stage of radiation damage | | 分子名称: | Chymotrypsin-like elastase family member 1, SODIUM ION, SULFATE ION | | 著者 | Petrova, T, Ginell, S, Kim, Y, Joachimiak, G, Joachimiak, A. | | 登録日 | 2010-04-22 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | X-ray-induced deterioration of disulfide bridges at atomic resolution.
Acta Crystallogr.,Sect.D, 66, 2010
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