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PDB: 137 件
7PVX
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BU of 7pvx by Molmil
Crystal structure of the c-Src SH3 domain mutant E93V-S94A-R95S-T96G-N112G-N113Y-T114N-E115H in complex with the synthetic peptide VSL12
分子名称: Isoform 1 of Proto-oncogene tyrosine-protein kinase Src, VSL12 peptide
著者Camara-Artigas, A, Salinas Garcia, M.C.
登録日2021-10-05
公開日2022-09-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Crystal structure of the c-Src SH3 domain mutants of the specificity region in complex with polyproline peptides
To be published
7PVW
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BU of 7pvw by Molmil
Crystal structure of the intertwined dimer of the c-Src SH3 domain E93V-S94A-R95S-T96G-N112G-N113Y-T114N-E115H mutant
分子名称: ACETATE ION, Isoform 1 of Proto-oncogene tyrosine-protein kinase Src, TETRAETHYLENE GLYCOL
著者Camara-Artigas, A, Salinas Garcia, M.C.
登録日2021-10-05
公開日2022-09-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The effect of the hinge loops composition in the domain swapping of the SH3 domain
To be published
4OMN
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BU of 4omn by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128E
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ...
著者Camara-Artigas, A, Bacarizo, J.
登録日2014-01-27
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
7NET
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BU of 7net by Molmil
Crystal structure of the v-Src SH3 domain W95R-I96T mutant
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Camara-Artigas, A, Salinas-Garcia, M.C.
登録日2021-02-04
公開日2021-06-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain.
Acta Crystallogr D Struct Biol, 77, 2021
7A36
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BU of 7a36 by Molmil
Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S in 7 M urea
分子名称: Proto-oncogene tyrosine-protein kinase Src, SODIUM ION, UREA
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S in 7 M urea
To be published
7A3E
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BU of 7a3e by Molmil
Intertwined dimer of the c-Src SH3 domain mutant T126S
分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ...
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Intertwined dimer of the c-Src SH3 domain mutant T126S
To be published
7A37
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BU of 7a37 by Molmil
Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S in 3 M urea
分子名称: Proto-oncogene tyrosine-protein kinase Src, UREA
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S in 3 M urea
To be published
7NER
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BU of 7ner by Molmil
Crystal structure of the v-Src SH3 domain Q128R mutant
分子名称: SULFATE ION, TETRAETHYLENE GLYCOL, v-Src SH3 domain
著者Camara-Artigas, A, Salinas-Garcia, M.C.
登録日2021-02-04
公開日2021-06-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain.
Acta Crystallogr D Struct Biol, 77, 2021
4QT7
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BU of 4qt7 by Molmil
Crystal structure of the c-Src SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein
分子名称: NS5A, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A, Bacarizo, J.
登録日2014-07-07
公開日2014-12-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of the c-Src-SH3 domain in complex with a proline-rich motif of NS5A protein from the hepatitis C virus.
J.Struct.Biol., 189, 2015
4JZ4
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BU of 4jz4 by Molmil
Crystal structure of chicken c-Src-SH3 domain: monomeric form
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2013-04-02
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4OML
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BU of 4oml by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128R
分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
著者Camara-Artigas, A, Bacarizo, J.
登録日2014-01-27
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
7A38
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BU of 7a38 by Molmil
Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 6.0
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 6.0
To be published
1P13
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BU of 1p13 by Molmil
Crystal Structure of the Src SH2 Domain Complexed with Peptide (SDpYANFK)
分子名称: CACODYLATE ION, Peptide, Proto-oncogene tyrosine-protein kinase Src
著者Sonnenburg, E.D, Bilwes, A, Hunter, T, Noel, J.P.
登録日2003-04-11
公開日2003-08-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region.
Biochemistry, 42, 2003
3FJ5
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BU of 3fj5 by Molmil
Crystal structure of the c-src-SH3 domain
分子名称: ACETATE ION, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ...
著者Camara-Artigas, A.
登録日2008-12-14
公開日2009-03-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Intertwined dimeric structure for the SH3 domain of the c-Src tyrosine kinase induced by polyethylene glycol binding
Febs Lett., 583, 2009
5EC7
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BU of 5ec7 by Molmil
Crystal structure of a chimeric c-Src-SH3 domain with the sequence of the RT-loop from the Abl-SH3 domain at pH 5.0
分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2015-10-20
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of a chimeric c-Src-SH3 domain with the sequence of the RT-loop from the Abl-SH3 domain at pH 5.0
to be published
7A39
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BU of 7a39 by Molmil
Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 7.0
分子名称: Proto-oncogene tyrosine-protein kinase Src, SULFATE ION
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 7.0
To be published
7A30
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BU of 7a30 by Molmil
Intertwined dimer of the c-Src SH3 domain mutant Q128E
分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ...
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Intertwined dimer of the c-Src SH3 domain mutant Q128E
To be published
7PW0
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BU of 7pw0 by Molmil
Crystal structure of the c-Src SH3 domain N112G-N113Y-T114N-E115H mutant
分子名称: Isoform 1 of Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A, Salinas Garcia, M.C.
登録日2021-10-05
公開日2022-09-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The effect of the hinge loops composition in the domain swapping of the SH3 domain
To be published
1F2F
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BU of 1f2f by Molmil
SRC SH2 THREF1TRP MUTANT
分子名称: PHOSPHATE ION, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
著者Kimber, M.S, Nachman, J, Cunningham, A.M, Gish, G.D, Pawson, T, Pai, E.F.
登録日2000-05-24
公開日2000-07-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for specificity switching of the Src SH2 domain.
Mol.Cell, 5, 2000
6XVN
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BU of 6xvn by Molmil
Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 1
分子名称: Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A, Plaza-Garrido, M.
登録日2020-01-22
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
6XVO
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BU of 6xvo by Molmil
Crystal structure of the intertwined dimer of the c-Src SH3 domain without ATCUN motif
分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
著者Camara-Artigas, A, Plaza-Garrido, M.
登録日2020-01-22
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase.
J.Biol.Inorg.Chem., 25, 2020
7WF5
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BU of 7wf5 by Molmil
c-Src in complex with ponatinib
分子名称: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Proto-oncogene tyrosine-protein kinase Src
著者Guo, M, Duan, Y, Dai, S, Chen, X, Chen, Y.
登録日2021-12-26
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Structural study of ponatinib in inhibiting SRC kinase.
Biochem.Biophys.Res.Commun., 598, 2022
7A3C
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BU of 7a3c by Molmil
Crystal structure of the c-Src SH3 domain mutant L100I at pH 3.0
分子名称: GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the c-Src SH3 domain mutant L100I at pH 3.0
To be published
7A3A
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BU of 7a3a by Molmil
Intertwined dimer of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 6.0
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, ...
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Intertwined dimer of the c-Src SH3 domain mutant V111L-N113S-T114S-Q128E at pH 6.0
To be published
5OB2
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Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12
分子名称: APP12, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2017-06-25
公開日2017-07-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12
to be published

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