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PDB: 39 件
6HYO
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BU of 6hyo by Molmil
Structure of ULK1 LIR motif bound to GABARAP
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Mouilleron, S, Wirth, M, Zhang, W, O'Reilly, N, Tooze, S, Johansen, T, Razi, M, Nyoni, L, Joshi, D.
登録日2018-10-22
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins.
Nat Commun, 10, 2019
7ZKR
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BU of 7zkr by Molmil
Human GABARAP in complex with stapled peptide Pen3-ortho
分子名称: CHLORIDE ION, Gamma-aminobutyric acid receptor-associated protein, ORTHO-XYLENE, ...
著者Ueffing, A, Brown, H, Willbold, D, Kritzer, J.A, Weiergraeber, O.H.
登録日2022-04-13
公開日2022-08-31
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy.
J.Am.Chem.Soc., 144, 2022
6YOP
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BU of 6yop by Molmil
Structure of SAMM50 LIR bound to GABARAP
分子名称: Sorting and assembly machinery component 50 homolog,Gamma-aminobutyric acid receptor-associated protein
著者Mouilleron, S, Wenxin, Z, Johansen, T, Tooze, S, Abudu, Y.P, Lamark, T.
登録日2020-04-14
公開日2021-04-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structure of SAMM50 LIR bound to GABARAP
To Be Published
6HYN
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BU of 6hyn by Molmil
Structure of ATG13 LIR motif bound to GABARAP
分子名称: Autophagy-related protein 13,Gamma-aminobutyric acid receptor-associated protein
著者Mouilleron, S, Wirth, M, Zhang, W, O'Reilly, N, Tooze, S, Johansen, T, Razi, M, Nyoni, L, Joshi, D.
登録日2018-10-22
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins.
Nat Commun, 10, 2019
7AA8
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BU of 7aa8 by Molmil
Structure of SCOC LIR bound to GABARAP
分子名称: Chimera made of SCOC (6-23) + linker (GS) + GABARAP,Gamma-aminobutyric acid receptor-associated protein
著者Lee, R, Mouilleron, S, Wirth, M, Zhang, W, O Reilly, N, Dhira, J, Tooze, S.
登録日2020-09-03
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.
J.Mol.Biol., 433, 2021
6HOG
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BU of 6hog by Molmil
Structure of VPS34 LIR motif bound to GABARAP
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3,Gamma-aminobutyric acid receptor-associated protein, ...
著者Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T.
登録日2018-09-17
公開日2019-02-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
8T2M
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BU of 8t2m by Molmil
Crystal structure of GABARAP in complex with the LIR of NSs4
分子名称: Non-structural protein S,Gamma-aminobutyric acid receptor-associated protein chimera
著者Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G.
登録日2023-06-06
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy.
Plos Pathog., 20, 2024
3D32
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BU of 3d32 by Molmil
Complex of GABA(A) receptor-associated protein (GABARAP) with a synthetic peptide
分子名称: CHLORIDE ION, Gamma-aminobutyric acid receptor-associated protein, K1 peptide, ...
著者Weiergraeber, O.H, Stangler, T, Willbold, D.
登録日2008-05-09
公開日2008-08-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Ligand Binding Mode of GABA(A) Receptor-Associated Protein.
J.Mol.Biol., 381, 2008
6HB9
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BU of 6hb9 by Molmil
Crystal structure of the GABARAP in complex with the UBA5 LIR motif
分子名称: Gamma-aminobutyric acid receptor-associated protein
著者Huber, J, Rogov, V, Akutsu, M.
登録日2018-08-10
公開日2019-05-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5.
Autophagy, 16, 2020
7BRQ
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BU of 7brq by Molmil
Crystal structure of human FAM134B LIR fused to human GABARAP
分子名称: GLYCEROL, Reticulophagy regulator 1,Gamma-aminobutyric acid receptor-associated protein
著者Yamasaki, A, Noda, N.N.
登録日2020-03-29
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.404 Å)
主引用文献Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes.
Nat Commun, 11, 2020
6HOJ
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BU of 6hoj by Molmil
Structure of Beclin1 LIR motif bound to GABARAP
分子名称: 1,2-ETHANEDIOL, Beclin-1,Gamma-aminobutyric acid receptor-associated protein, SULFATE ION
著者Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T.
登録日2018-09-17
公開日2019-02-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
8W6A
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BU of 8w6a by Molmil
Crystal structure of TAX1BP1 LIR region in complex with GABARAP
分子名称: Gamma-aminobutyric acid receptor-associated protein, Tax1-binding protein 1
著者Zhang, M.F, Pan, L.F.
登録日2023-08-28
公開日2024-07-10
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Mechanistic insights into the interactions of TAX1BP1 with RB1CC1 and mammalian ATG8 family proteins.
Proc.Natl.Acad.Sci.USA, 121, 2024
7ZL7
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BU of 7zl7 by Molmil
Human GABARAP in complex with stapled peptide Pen8-ortho
分子名称: CHLORIDE ION, Gamma-aminobutyric acid receptor-associated protein, ORTHO-XYLENE, ...
著者Ueffing, A, Brown, H, Willbold, D, Kritzer, J.A, Weiergraeber, O.H.
登録日2022-04-14
公開日2022-08-31
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy.
J.Am.Chem.Soc., 144, 2022
6HYL
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BU of 6hyl by Molmil
Structure of PCM1 LIR motif bound to GABARAP
分子名称: Pericentriolar material 1 protein,Gamma-aminobutyric acid receptor-associated protein
著者Mouilleron, S, Wirth, M, Zhang, W, O'Reilly, N, Tooze, S, Johansen, T, Razi, M, Nyoni, L, Joshi, D.
登録日2018-10-22
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.559 Å)
主引用文献Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins.
Nat Commun, 10, 2019
8T33
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BU of 8t33 by Molmil
Crystal structure of K46 acetylated GABARAP in complex with the LIR of TP53INP2/DOR
分子名称: ACETATE ION, Gamma-aminobutyric acid receptor-associated protein, Tumor protein p53-inducible nuclear protein 2, ...
著者Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G.
登録日2023-06-07
公開日2024-05-22
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR.
Autophagy, 2024
6HOK
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BU of 6hok by Molmil
Structure of Beclin1 LIR (S96E) motif bound to GABARAP
分子名称: 1,2-ETHANEDIOL, Beclin-1,Gamma-aminobutyric acid receptor-associated protein
著者Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T.
登録日2018-09-17
公開日2019-02-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
7YO9
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BU of 7yo9 by Molmil
Crystal structure of fusion protein of human TP53INP2 LIR and human GABARAP
分子名称: ISOPROPYL ALCOHOL, PHOSPHATE ION, Tumor protein p53-inducible nuclear protein 2,Gamma-aminobutyric acid receptor-associated protein
著者Yamasaki, A, Noda, N.N.
登録日2022-08-01
公開日2022-11-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Development of new tools to study membrane-anchored mammalian Atg8 proteins.
Autophagy, 19, 2023
1GNU
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BU of 1gnu by Molmil
GABA(A) receptor associated protein GABARAP
分子名称: GABARAP, NICKEL (II) ION
著者Knight, D, Harris, R, Moss, S, Driscoll, P.C, Keep, N.H.
登録日2001-10-09
公開日2001-12-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The X-Ray Crystal Structure and Putative Ligand-Derived Peptide Binding Properties of Gamma-Aminobutyric Acid Receptor Type a Receptor-Associated Protein
J.Biol.Chem., 277, 2002
7LT6
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BU of 7lt6 by Molmil
Structure of Partial Beta-Hairpin LIR from FNIP2 Bound to GABARAP
分子名称: Folliculin-interacting protein 2,Gamma-aminobutyric acid receptor-associated protein
著者Appleton, B.A.
登録日2021-02-18
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis.
Sci Adv, 7, 2021
6HYM
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BU of 6hym by Molmil
Structure of PCM1 LIR motif bound to GABARAP
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Pericentriolar material 1 protein,Gamma-aminobutyric acid receptor-associated protein
著者Mouilleron, S, Wirth, M, Zhang, W, O'Reilly, N, Tooze, S, Johansen, T, Razi, M, Nyoni, L, Joshi, D.
登録日2018-10-22
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins.
Nat Commun, 10, 2019
8T2N
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BU of 8t2n by Molmil
Crystal structure of GABARAP in complex with the LIR of NSs3
分子名称: Gamma-aminobutyric acid receptor-associated protein, Non-structural protein S
著者Ali, M.G.H, Wahba, H.M, Cyr, N, Omichinski, J.G.
登録日2023-06-06
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy.
Plos Pathog., 20, 2024
4XC2
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BU of 4xc2 by Molmil
Crystal structure of GABARAP in complex with KBTBD6 LIR peptide
分子名称: GABA(A) receptor-associated protein, Kelch repeat and BTB domain-containing protein 6
著者Huber, J, Genau, H.M, Baschieri, F, Doetsch, V, Farhan, H, Rogov, V.V, Behrends, C, Akutsu, M.
登録日2014-12-17
公開日2015-03-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献CUL3-KBTBD6/KBTBD7 Ubiquitin Ligase Cooperates with GABARAP Proteins to Spatially Restrict TIAM1-RAC1 Signaling.
Mol.Cell, 57, 2015
7BRT
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BU of 7brt by Molmil
Crystal structure of Sec62 LIR fused to GABARAP
分子名称: Translocation protein SEC62,Gamma-aminobutyric acid receptor-associated protein
著者Yamasaki, A, Noda, N.N.
登録日2020-03-30
公開日2020-07-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes.
Nat Commun, 11, 2020
5DPS
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BU of 5dps by Molmil
Crystal structure of PLEKHM1 LIR-fused human GABARAP_2-117
分子名称: Pleckstrin homology domain-containing family M member 1,Gamma-aminobutyric acid receptor-associated protein
著者Ravichandran, A.C, Suzuki, H, Dobson, R.C.J.
登録日2015-09-14
公開日2016-09-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and functional analysis of the GABARAP interaction motif (GIM).
EMBO Rep., 18, 2017
7BV4
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BU of 7bv4 by Molmil
Crystal structure of STX17 LIR region in complex with GABARAP
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein, ...
著者Li, Y, Pan, L.F.
登録日2020-04-09
公開日2020-09-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion.
Proc.Natl.Acad.Sci.USA, 117, 2020

 

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