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PDB: 34 件
2M16
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BU of 2m16 by Molmil
P75/LEDGF PWWP Domain
分子名称: PC4 and SFRS1-interacting protein
著者Crowe, B.L, Foster, M.P.
登録日2012-11-18
公開日2013-02-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes.
Nucleic Acids Res., 41, 2013
2MSR
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BU of 2msr by Molmil
Solution structure of LEDGF/p75 IBD in complex with MLL1 peptide (140-160)
分子名称: Histone-lysine N-methyltransferase 2A, PC4 and SFRS1-interacting protein
著者Cermakova, K, Tesina, P, Demeulemeester, J, El Ashkar, S, Mereau, H, Schwaller, J, Rezacova, P, Veverka, V, De Rijck, J.
登録日2014-08-05
公開日2014-08-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Validation and Structural Characterization of the LEDGF/p75-MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia.
Cancer Res., 74, 2014
2MTN
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BU of 2mtn by Molmil
Solution structure of MLL-IBD complex
分子名称: Histone-lysine N-methyltransferase 2A, PC4 and SFRS1-interacting protein fusion
著者Cierpicki, T, Pollock, J, Murai, M.
登録日2014-08-23
公開日2014-12-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV.
Blood, 124, 2014
2N3A
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BU of 2n3a by Molmil
Solution structure of LEDGF/p75 IBD in complex with POGZ peptide (1389-1404)
分子名称: PC4 and SFRS1-interacting protein, Pogo transposable element with ZNF domain
著者Tesina, P, Cermakova, K, Horejsi, M, Prochazkova, K, Fabry, M, Sharma, S, Christ, F, Demeulemeester, J, Debyser, Z, De Rijck, J, Veverka, V, Rezacova, P.
登録日2015-05-26
公開日2015-08-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif.
Nat Commun, 6, 2015
5YI9
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BU of 5yi9 by Molmil
Solution structure of the LEDGF/p75 IBD - JPO2 (aa 56-91) complex
分子名称: PC4 and SFRS1-interacting protein,Cell division cycle-associated 7-like protein
著者Veverka, V.
登録日2017-10-03
公開日2018-08-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6ZV0
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BU of 6zv0 by Molmil
TFIIS N-terminal domain (TND) from human LEDGF/p75
分子名称: PC4 and SFRS1-interacting protein
著者Veverka, V.
登録日2020-07-23
公開日2021-12-01
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Science, 374, 2021
6TVM
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BU of 6tvm by Molmil
LEDGF/p75 dimer (residues 345-467)
分子名称: PC4 and SFRS1-interacting protein
著者Lux, V, Veverka, V.
登録日2020-01-10
公開日2020-09-09
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Molecular Mechanism of LEDGF/p75 Dimerization.
Structure, 28, 2020
3ZEH
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BU of 3zeh by Molmil
Solution structure of the Hs. PSIP1 PWWP domain
分子名称: PC4 AND SFRS1-INTERACTING PROTEIN
著者van Ingen, H, van Nuland, R, Timmers, H.T.M, Boelens, R.
登録日2012-12-05
公開日2013-05-22
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Nucleosomal DNA Binding Drives the Recognition of H3K36-Methylated Nucleosomes by the Psip1-Pwwp Domain.
Epigenetics Chromatin, 6, 2013
1Z9E
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BU of 1z9e by Molmil
Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
分子名称: PC4 and SFRS1 interacting protein 2
著者Cherepanov, P, Sun, Z.-Y.J, Rahman, S, Maertens, G, Wagner, G, Engelman, A.
登録日2005-04-01
公開日2005-05-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
Nat.Struct.Mol.Biol., 12, 2005
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