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PDB: 172 件

5SYF
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BU of 5syf by Molmil
High-resolution cryo-EM reconstruction of Taxol-stabilized microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Kellogg, E.H, Nogales, E.
登録日2016-08-11
公開日2017-02-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures.
J. Mol. Biol., 429, 2017
3JAT
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BU of 3jat by Molmil
Cryo-EM structure of GMPCPP-microtubule (14 protofilaments) decorated with kinesin
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Zhang, R, Nogales, E.
登録日2015-06-20
公開日2015-08-12
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
6B0C
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BU of 6b0c by Molmil
KLP10A-AMPPNP in complex with curved tubulin and a microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp10A, ...
著者Benoit, M.P.M.H, Asenjo, A.B, Sosa, H.
登録日2017-09-14
公開日2018-05-02
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s.
Nat Commun, 9, 2018
7U0F
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BU of 7u0f by Molmil
HIV-1 Rev in complex with tubulin
分子名称: Protein Rev, Tubulin alpha-1A chain, Tubulin beta chain
著者Eren, E.
登録日2022-02-18
公開日2023-08-23
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural basis of microtubule depolymerization by the kinesin-like activity of HIV-1 Rev.
Structure, 31, 2023
8QAU
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BU of 8qau by Molmil
Outer kinetochore Ndc80-Dam1 alpha/beta-tubulin complex
分子名称: DASH complex subunit DAM1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Muir, K.W, Barford, D.
登録日2023-08-23
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Mechanism of outer kinetochore assembly on microtubules and its regulation by mitotic error correction
Biorxiv, 2023
1SA0
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BU of 1sa0 by Molmil
TUBULIN-COLCHICINE: STATHMIN-LIKE DOMAIN COMPLEX
分子名称: 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ravelli, R.B, Gigant, B, Curmi, P.A, Jourdain, I, Lachkar, S, Sobel, A, Knossow, M.
登録日2004-02-06
公開日2004-03-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.58 Å)
主引用文献Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.
Nature, 428, 2004
7YSO
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BU of 7yso by Molmil
Tubulin heterodimer structure of GDP-1 state in solution
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Tubulin alpha-1B chain, ...
著者Zhou, J, Wang, H.-W.
登録日2022-08-12
公開日2023-10-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insights into the mechanism of GTP initiation of microtubule assembly.
Nat Commun, 14, 2023
6MZE
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BU of 6mze by Molmil
Structural Basis of Tubulin Recruitment and Assembly by Microtubule Polymerases with Tumor Overexpressed Gene (TOG) Domain Arrays
分子名称: Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Nithianantham, S, Al-Bassam, J.
登録日2018-11-05
公開日2018-11-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural basis of tubulin recruitment and assembly by microtubule polymerases with Tumor Overexpressed Gene (TOG) domain arrays.
Elife, 7, 2018
6KIQ
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BU of 6kiq by Molmil
Complex of yeast cytoplasmic dynein MTBD-High and MT with DTT
分子名称: Alpha tubulin, Dynein heavy chain, cytoplasmic, ...
著者Komori, Y, Nishida, N, Shimada, I, Kikkawa, M.
登録日2019-07-19
公開日2020-03-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
6O2Q
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BU of 6o2q by Molmil
Acetylated Microtubules
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E.
登録日2019-02-24
公開日2019-05-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Effects of alpha-tubulin acetylation on microtubule structure and stability.
Proc.Natl.Acad.Sci.USA, 116, 2019
8RC1
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BU of 8rc1 by Molmil
MAP7 MTBD (microtubule binding domain) decorated microtubule protofilament
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Bangera, M, Moores, C.A.
登録日2023-12-05
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献A structural and dynamic visualization of the interaction between MAP7 and microtubules.
Nat Commun, 15, 2024
1TUB
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BU of 1tub by Molmil
TUBULIN ALPHA-BETA DIMER, ELECTRON DIFFRACTION
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, TAXOTERE, ...
著者Nogales, E, Downing, K.H.
登録日1997-09-23
公開日1998-10-07
最終更新日2024-06-05
実験手法ELECTRON CRYSTALLOGRAPHY (3.7 Å)
主引用文献Structure of the alpha beta tubulin dimer by electron crystallography.
Nature, 391, 1998
6B0I
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BU of 6b0i by Molmil
Apo KLP10A in complex with a microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp10A, ...
著者Benoit, M.P.M.H, Asenjo, A.B, Sosa, H.
登録日2017-09-14
公開日2018-05-02
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s.
Nat Commun, 9, 2018
6EW0
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BU of 6ew0 by Molmil
Cryo-EM structure of GDP-microtubule co-polymerised with doublecortin and supplemented with Taxol
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Manka, S.W.
登録日2017-11-03
公開日2018-07-04
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability.
Nat. Struct. Mol. Biol., 25, 2018
6EVZ
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BU of 6evz by Molmil
Cryo-EM structure of GDP-microtubule co-polymerised with doublecortin
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Manka, S.W.
登録日2017-11-03
公開日2018-07-04
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability.
Nat. Struct. Mol. Biol., 25, 2018
6TIW
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BU of 6tiw by Molmil
Human kinesin-5 motor domain in the GSK state bound to microtubules (Conformation 2)
分子名称: 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ...
著者Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M.
登録日2019-11-22
公開日2020-03-04
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy.
Structure, 28, 2020
6TA3
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BU of 6ta3 by Molmil
Human kinesin-5 motor domain in the GSK-1 state bound to microtubules (Conformation 1)
分子名称: 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ...
著者Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M.
登録日2019-10-29
公開日2020-04-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy.
Structure, 28, 2020
7RX0
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BU of 7rx0 by Molmil
Complex of AMPPNP-Kif7 and Gli2 Zinc-Finger domain bound to microtubules
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF7, MAGNESIUM ION, ...
著者Mani, N, Wilson-Kubalek, E.M, Haque, F, Freniere, C, Milligan, R.A, Subramanian, R.
登録日2021-08-20
公開日2022-06-15
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Cytoskeletal regulation of a transcription factor by DNA mimicry via coiled-coil interactions.
Nat.Cell Biol., 24, 2022
7RS5
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BU of 7rs5 by Molmil
Cryo-EM structure of Kip3 (AMPPNP) bound to Taxol-Stabilized Microtubules
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Hernandez-Lopez, R.A, Leschziner, A.E, Arellano-Santoyo, H, Pellman, D, Stokasimov, E, Wang, R.Y.-R.
登録日2021-08-10
公開日2022-08-17
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Multimodal tubulin binding by the yeast kinesin-8, Kip3, underlies its motility and depolymerization
Biorxiv, 2021
7YSP
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BU of 7ysp by Molmil
Tubulin heterodimer structure of GDP-2 state in solution
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Tubulin alpha-1B chain, ...
著者Zhou, J, Wang, H.-W.
登録日2022-08-12
公開日2023-10-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insights into the mechanism of GTP initiation of microtubule assembly.
Nat Commun, 14, 2023
3JAW
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BU of 3jaw by Molmil
Atomic model of a microtubule seam based on a cryo-EM reconstruction of the EB3-bound microtubule (merged dataset containing tubulin bound to GTPgammaS, GMPCPP, and GDP)
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Zhang, R, Nogales, E.
登録日2015-06-30
公開日2015-08-12
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
6CVN
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BU of 6cvn by Molmil
Model of synthetic tau (R2x4) bound to the microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Nogales, E, Kellogg, E.H.
登録日2018-03-28
公開日2018-05-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Near-atomic model of microtubule-tau interactions.
Science, 360, 2018
7TR3
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BU of 7tr3 by Molmil
CaKip3[2-482] - AMP-PNP in complex with a dolastatin-10-stabilized tubulin ring
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein, ...
著者Benoit, M.P.M.H, Asenjo, A.B, Hunter, B, Allingham, J.S, Sosa, H.
登録日2022-01-27
公開日2022-07-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape.
Nat Commun, 13, 2022
6KIO
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BU of 6kio by Molmil
Complex of yeast cytoplasmic dynein MTBD-High and MT without DTT
分子名称: Dynein heavy chain, cytoplasmic, Tubulin alpha-1A chain, ...
著者Komori, Y, Nishida, N, Shimada, I, Kikkawa, M.
登録日2019-07-19
公開日2020-03-04
最終更新日2020-03-11
実験手法ELECTRON MICROSCOPY (3.94 Å)
主引用文献Structural basis for two-way communication between dynein and microtubules.
Nat Commun, 11, 2020
1FFX
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BU of 1ffx by Molmil
TUBULIN:STATHMIN-LIKE DOMAIN COMPLEX
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, PROTEIN (STATHMIN-LIKE DOMAIN OF RB3), ...
著者Gigant, B, Martin-Barbey, C, Knossow, M.
登録日2000-07-26
公開日2000-09-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献The 4 A X-ray structure of a tubulin:stathmin-like domain complex.
Cell(Cambridge,Mass.), 102, 2000

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