5JC9
| Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | 著者 | Cocozaki, A, Ferguson, A. | 登録日 | 2016-04-14 | 公開日 | 2016-07-06 | 最終更新日 | 2016-08-03 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
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7OE1
| 30S ribosomal subunit from E. coli | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Maksimova, E, Korepanov, A, Baymukhametov, T, Kravchenko, O, Stolboushkina, E. | 登録日 | 2021-04-30 | 公開日 | 2021-07-14 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | RbfA Is Involved in Two Important Stages of 30S Subunit Assembly: Formation of the Central Pseudoknot and Docking of Helix 44 to the Decoding Center. Int J Mol Sci, 22, 2021
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5MDW
| Structure of ArfA(A18T) and RF2 bound to the 70S ribosome (pre-accommodated state) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V. | 登録日 | 2016-11-13 | 公開日 | 2016-12-14 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Translational termination without a stop codon. Science, 354, 2016
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6SZS
| Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Muller, C, Beckert, B, Wilson, D.N. | 登録日 | 2019-10-02 | 公開日 | 2019-12-04 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis. Nat Commun, 10, 2019
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7AC7
| Structure of accomodated trans-translation complex on E. Coli stalled ribosome. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | 登録日 | 2020-09-10 | 公開日 | 2021-08-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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4WF1
| Crystal structure of the E. coli ribosome bound to negamycin. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C. | 登録日 | 2014-09-11 | 公開日 | 2014-11-05 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome. Proc.Natl.Acad.Sci.USA, 111, 2014
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8PKL
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7O5H
| Ribosomal methyltransferase KsgA bound to small ribosomal subunit | 分子名称: | 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | 著者 | Stephan, N.C, Ries, A.B, Boehringer, D, Ban, N. | 登録日 | 2021-04-08 | 公開日 | 2021-06-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of successive adenosine modifications by the conserved ribosomal methyltransferase KsgA. Nucleic Acids Res., 49, 2021
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6VWL
| 70S ribosome bound to HIV frameshifting stem-loop (FSS) and P/E tRNA (rotated conformation) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loerch, S, Bao, C, Ling, C, Korostelev, A.A, Grigorieff, N, Ermolenko, D.M. | 登録日 | 2020-02-20 | 公開日 | 2020-06-03 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding. Elife, 9, 2020
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5MGP
| Structural basis for ArfA-RF2 mediated translation termination on stop-codon lacking mRNAs | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Huter, P, Mueller, C, Beckert, B, Arenz, S, Berninghausen, O, Beckmann, R, Wilson, N.D. | 登録日 | 2016-11-21 | 公開日 | 2016-12-14 | 最終更新日 | 2017-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for ArfA-RF2-mediated translation termination on mRNAs lacking stop codons. Nature, 541, 2017
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8G7S
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8G7Q
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4WWW
| Crystal structure of the E. coli ribosome bound to CEM-101 | 分子名称: | (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S rRNA, 23S rRNA, ... | 著者 | Dunkle, J.A, Zhang, W, Cate, J.H.D, Mankin, A.S. | 登録日 | 2014-11-12 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis. Antimicrob. Agents Chemother., 54, 2010
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4V7U
| Crystal structure of the E. coli ribosome bound to erythromycin. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D. | 登録日 | 2010-08-15 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proc.Natl.Acad.Sci.USA, 107, 2010
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6X7K
| Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | 登録日 | 2020-05-30 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
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7PJY
| Structure of the 70S-EF-G-GDP ribosome complex with tRNAs in chimeric state 1 (CHI1-EF-G-GDP) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | 登録日 | 2021-08-24 | 公開日 | 2021-10-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural mechanism of GTPase-powered ribosome-tRNA movement. Nat Commun, 12, 2021
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7PJV
| Structure of the 70S-EF-G-GDP-Pi ribosome complex with tRNAs in hybrid state 1 (H1-EF-G-GDP-Pi) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | 登録日 | 2021-08-24 | 公開日 | 2021-10-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural mechanism of GTPase-powered ribosome-tRNA movement. Nat Commun, 12, 2021
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8FZD
| Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with apoRF3, RF1, P- and E-site tRNAPhe (Composite state I-B) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZI
| Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-B) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZG
| Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF3-GDPCP, RF1, P- and E-site tRNAPhe (Composite state II-A) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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5J8A
| Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | 著者 | Cocozaki, A, Ferguson, A. | 登録日 | 2016-04-07 | 公開日 | 2016-07-06 | 最終更新日 | 2016-08-03 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
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5MDZ
| Structure of the 70S ribosome (empty A site) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V. | 登録日 | 2016-11-13 | 公開日 | 2016-12-14 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Translational termination without a stop codon. Science, 354, 2016
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6OM6
| Structure of trans-translation inhibitor bound to E. coli 70S ribosome with P site tRNA | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Hoffer, E.D, Mehrani, A, Keiler, K.C, Stagg, S.M, Dunham, C.M. | 登録日 | 2019-04-18 | 公開日 | 2021-02-10 | 最終更新日 | 2021-09-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo. Nat Commun, 12, 2021
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8Q4F
| Structure of arbekacin bound Escherichia coli 70S ribosome | 分子名称: | 16S rRNA, 23S rRNA, 50S ribosomal protein L16, ... | 著者 | Majumdar, S, Parajuli, N.P, Ge, X, Emmerich, A, Sanyal, S. | 登録日 | 2023-08-06 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of arbekacin bound Escherichia coli 70S ribosome To be published
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6ENU
| Polyproline-stalled ribosome in the presence of elongation-factor P (EF-P) | 分子名称: | 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Huter, P, Arenz, S, Wilson, D.N. | 登録日 | 2017-10-06 | 公開日 | 2017-11-22 | 最終更新日 | 2018-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P. Mol. Cell, 68, 2017
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