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PDB: 283 件

7PY6
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CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in less-swiveled conformation)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhu, C, Guo, X, Weixlbaumer, A.
登録日2021-10-09
公開日2022-03-23
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
6FLP
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BU of 6flp by Molmil
CryoEM structure of E.coli RNA polymerase paused elongation complex without RNA hairpin bound to NusA
分子名称: DNA (30-MER), DNA (39-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Guo, X, Weixlbaumer, A.
登録日2018-01-26
公開日2018-03-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural Basis for NusA Stabilized Transcriptional Pausing.
Mol. Cell, 69, 2018
8AD1
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RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Dey, S, Weixlbaumer, A.
登録日2022-07-07
公開日2022-10-19
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
8AC0
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BU of 8ac0 by Molmil
RNA polymerase at U-rich pause bound to regulatory RNA putL - active, closed clamp state
分子名称: DNA Non-template strand, DNA Template strand, DNA-directed RNA polymerase subunit alpha, ...
著者Weixlbaumer, A, Dey, S.
登録日2022-07-05
公開日2022-10-19
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
5UAH
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BU of 5uah by Molmil
Escherichia coli RNA polymerase and Rifampin complex, RpoB D516V mutant
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Molodtsov, V, Scharf, N.T, Stefan, M.A, Garcia, G.A, Murakami, K.S.
登録日2016-12-19
公開日2017-01-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis.
Mol. Microbiol., 103, 2017
6Z9T
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BU of 6z9t by Molmil
Transcription termination intermediate complex 5
分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
著者Said, N, Hilal, T, Loll, B, Wahl, M.C.
登録日2020-06-04
公開日2020-11-04
最終更新日2021-02-03
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
8E6Z
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BU of 8e6z by Molmil
Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, dC75 rut mimic RNA, Mg-ADP-BeF3, and NusG; TEC part
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Molodtsov, V, Wang, C, Ebright, R.H.
登録日2022-08-23
公開日2022-09-07
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
6GH6
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BU of 6gh6 by Molmil
Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme intermediate partially loaded complex
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Glyde, R, Ye, F.Z, Zhang, X.D.
登録日2018-05-04
公開日2018-07-04
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation.
Mol. Cell, 70, 2018
6CUX
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BU of 6cux by Molmil
Escherichia coli RpoB S531L mutant RNA polymerase holoenzyme in complex with Kanglemycin A
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Molodtsov, V, Murakami, K.S.
登録日2018-03-26
公開日2018-07-25
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (4.104 Å)
主引用文献Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis.
Mol. Cell, 72, 2018
7KHC
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BU of 7khc by Molmil
Escherichia coli RNA polymerase and rrnBP1 promoter closed complex
分子名称: CHAPSO, DNA (18 MER), DNA (63-MER), ...
著者Shin, Y, Qayyum, M.Z, Murakami, K.S.
登録日2020-10-20
公開日2020-10-28
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
6UTY
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BU of 6uty by Molmil
E. coli sigma-S transcription initiation complex with a mismatching CTP ("Old" crystal soaked with CTP for 30 minutes)
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.15 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
5IPM
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BU of 5ipm by Molmil
SigmaS-transcription initiation complex with 4-nt nascent RNA
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Liu, B, Zuo, Y, Steitz, T.A.
登録日2016-03-09
公開日2016-03-30
最終更新日2016-06-22
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
7PYJ
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BU of 7pyj by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in less-swiveled conformation)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhu, C, Guo, X, Weixlbaumer, A.
登録日2021-10-10
公開日2022-03-23
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7W5Y
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BU of 7w5y by Molmil
Cryo-EM structure of SoxS-dependent transcription activation complex with fpr promoter DNA
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Lin, W, Feng, Y.
登録日2021-11-30
公開日2022-10-26
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis of three different transcription activation strategies adopted by a single regulator SoxS.
Nucleic Acids Res., 50, 2022
7ADE
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BU of 7ade by Molmil
Transcription termination complex IVa
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ...
著者Said, N, Hilal, T, Loll, B, Wahl, C.M.
登録日2020-09-14
公開日2020-11-25
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
8E5K
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BU of 8e5k by Molmil
Escherichia coli Rho-dependent transcription pre-termination complex containing 21 nt long RNA spacer, Mg-ADP-BeF3, and NusG; TEC part
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Molodtsov, V, Wang, C.
登録日2022-08-22
公開日2022-09-07
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
7BEG
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BU of 7beg by Molmil
Structures of class I bacterial transcription complexes
分子名称: Class I pacrA promoter non-template DNA, Class I pacrA promoter template DNA, DNA-directed RNA polymerase subunit alpha, ...
著者Ye, F.Z, Hao, M, Zhang, X.D.
登録日2020-12-23
公開日2021-12-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
Adv Sci, 9, 2022
6UU6
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BU of 6uu6 by Molmil
E. coli sigma-S transcription initiation complex with a 4-nt RNA and a UTP ("Old" crystal soaked with UTP, ddCTP, and dinucleotide ApG for 30 minutes)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.201 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
4JK2
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BU of 4jk2 by Molmil
X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with guanosine pentaphosphate (pppGpp)
分子名称: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ...
著者Murakami, K.S.
登録日2013-03-09
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.201 Å)
主引用文献Differential regulation by ppGpp versus pppGpp in Escherichia coli.
Nucleic Acids Res., 41, 2013
4ZH2
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BU of 4zh2 by Molmil
Crystal structure of Escherichia coli RNA polymerase in complex with CBR703
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Feng, Y, Ebright, R.H.
登録日2015-04-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.204 Å)
主引用文献Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Structure, 23, 2015
7C17
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BU of 7c17 by Molmil
The cryo-EM structure of E. coli CueR transcription activation complex with fully duplex promoter DNA
分子名称: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Fang, C.L, Zhang, Y.
登録日2020-05-02
公開日2020-09-30
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.22 Å)
主引用文献CueR activates transcription through a DNA distortion mechanism.
Nat.Chem.Biol., 17, 2021
6C9Y
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BU of 6c9y by Molmil
Cryo-EM structure of E. coli RNAP sigma70 holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yenool, D, Jiang, W, Murakami, K.S.
登録日2018-01-29
公開日2018-02-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation.
J. Biol. Chem., 293, 2018
8E6X
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BU of 8e6x by Molmil
Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, lambda-tR1 rut RNA, Mg-ADP-BeF3, and NusG; TEC part
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Molodtsov, V, Wang, C.
登録日2022-08-23
公開日2022-09-07
最終更新日2023-02-22
実験手法ELECTRON MICROSCOPY (4.27 Å)
主引用文献Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
6PB6
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BU of 6pb6 by Molmil
The E. coli class-II CAP-dependent transcription activation complex at the state 2
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Shi, W.
登録日2019-06-13
公開日2020-03-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.29 Å)
主引用文献Visualization of two architectures in class-II CAP-dependent transcription activation
Plos Biol., 18, 2020
5VSW
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BU of 5vsw by Molmil
X-ray crystal structure of Escherichia coli RNA polymerase and DksA/ppGpp complex
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Murakami, K.S, Molodtsov, V.
登録日2017-05-12
公開日2017-06-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (4.295 Å)
主引用文献Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA.
Mol. Cell, 69, 2018

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件を2024-07-10に公開中

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