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PDB: 226 件
7QL0
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BU of 7ql0 by Molmil
In vitro assembled 266/297 - 391 tau filaments with MgSO4 and NaCl (15c)
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W.
登録日2021-12-19
公開日2022-02-16
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKI
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BU of 7qki by Molmil
In vitro assembled 297-408 S396D S400D T403D S404D tau filaments (42a)
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W.
登録日2021-12-17
公開日2022-02-16
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QJY
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BU of 7qjy by Molmil
In vitro assembled 266/297 - 391 tau filaments with LiCl (9a)
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W.
登録日2021-12-17
公開日2022-02-16
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
8Q9D
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BU of 8q9d by Molmil
Tau - CTE-MIA15 (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-20
公開日2023-09-20
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q8Z
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BU of 8q8z by Molmil
Tau - CTE-MIA7 (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-19
公開日2023-09-20
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
7QKX
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BU of 7qkx by Molmil
In vitro assembled 266/297 - 391 tau filaments with MgSO4 and NaCl (15b)
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W.
登録日2021-12-19
公開日2022-02-16
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
8BGS
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BU of 8bgs by Molmil
Tau Paired Helical Filament from Extracellular Vesicles from Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Behr, T.S, Ryskeldi-Falcon, B.
登録日2022-10-28
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.
Biorxiv, 2023
7QKH
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BU of 7qkh by Molmil
In vitro assembled 258-391 tau filaments with sodium azide, (41a)
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W.
登録日2021-12-17
公開日2022-03-02
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
8ZWM
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BU of 8zwm by Molmil
Heparin bound Tau fibril polymorph 4
分子名称: Isoform Tau-F of Microtubule-associated protein tau
著者Tao, Y.Q, Liu, C, Li, D.
登録日2024-06-13
公開日2024-07-03
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Heparin bound Tau fibril polymorph 4
To Be Published
6GX5
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BU of 6gx5 by Molmil
Narrow Pick Filament from Pick's disease brain
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zhang, W, Murzin, A.G, Murshudov, G, Garringer, H.J, Vidal, R, Crowther, R.A, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2018-06-26
公開日2018-09-12
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of filaments from Pick's disease reveal a novel tau protein fold.
Nature, 561, 2018
8OTC
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BU of 8otc by Molmil
CTE typeII tau filament from Guam ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8Q9K
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BU of 8q9k by Molmil
Tau - CTE-LIA13 (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-20
公開日2023-09-06
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
7QL4
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BU of 7ql4 by Molmil
in vitro assembled tau filaments with structures like Paired Helical Filaments from Alzheimer's Disease
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W.
登録日2021-12-19
公開日2022-02-16
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
6HRE
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BU of 6hre by Molmil
Paired helical filament from sporadic Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2018-09-26
公開日2018-10-10
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
6TJO
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BU of 6tjo by Molmil
Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration
分子名称: Microtubule-associated protein tau
著者Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W.
登録日2019-11-26
公開日2020-02-05
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
9BBM
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BU of 9bbm by Molmil
PHF filament generated from 4E-Tau(297-407) under neutral Mg2+ condition
分子名称: Isoform Tau-F of Microtubule-associated protein tau
著者Duan, P, El Mammeri, N.
登録日2024-04-06
公開日2024-05-08
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Milligram-scale assembly and NMR fingerprint of tau fibrils adopting the Alzheimer's disease fold.
J.Biol.Chem., 300, 2024
6CVJ
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BU of 6cvj by Molmil
Model of synthetic tau (four tandem repeats of first repeat sequence) bound to the microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Nogales, E, Kellogg, E.H.
登録日2018-03-28
公開日2018-05-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Near-atomic model of microtubule-tau interactions.
Science, 360, 2018
8QCP
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BU of 8qcp by Molmil
Tau - AD-LIA8 (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-28
公開日2023-09-06
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
7QKV
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BU of 7qkv by Molmil
In vitro assembled tau filaments with MgSO4 and NaCl (15a)
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W.
登録日2021-12-19
公開日2022-02-16
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
8Q7M
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BU of 8q7m by Molmil
Tau - AD-MIA7 (tau intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-16
公開日2023-08-30
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
7QKJ
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BU of 7qkj by Molmil
In vitro assembled 266/297 - 391 tau filaments with MgCl2 and NaCl (14b)
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W.
登録日2021-12-17
公開日2022-03-23
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
8BGV
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BU of 8bgv by Molmil
Tau Paired Helical Filament from Cellular Fraction of Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Behr, T.S, Ryskeldi-Falcon, B.
登録日2022-10-28
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.
Biorxiv, 2023
8Q7P
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BU of 8q7p by Molmil
Tau - AD-MIA8 (intermediate amyloid)
分子名称: Isoform Tau-D of Microtubule-associated protein tau
著者Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
登録日2023-08-16
公開日2023-08-30
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
7QJV
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BU of 7qjv by Molmil
In vitro assembled tau filaments into Quadruple Helical Filaments type 1 (2c)
分子名称: Microtubule-associated protein tau
著者Lovestam, S, Scheres, S.H.W.
登録日2021-12-17
公開日2022-02-16
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7P6D
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BU of 7p6d by Molmil
Argyrophilic grain disease type 1 tau filament
分子名称: Microtubule-associated protein tau
著者Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
登録日2021-07-15
公開日2021-09-15
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure-based classification of tauopathies.
Nature, 598, 2021

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件を2024-07-10に公開中

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