6CQL
 
 | | Crystal structure of F24 TCR -DR11-RQ13 peptide complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F24 alpha chain, F24 beta Chain, ... | | 著者 | Farenc, C, Gras, S, Rossjohn, J. | | 登録日 | 2018-03-15 | | 公開日 | 2018-06-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | CD4+T cell-mediated HLA class II cross-restriction in HIV controllers.
Sci Immunol, 3, 2018
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2EYR
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2ICW
 | | Crystal structure of a complete ternary complex between TCR, superantigen, and peptide-MHC class II molecule | | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... | | 著者 | Wang, L, Zhao, Y, Li, H. | | 登録日 | 2006-09-13 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC.
Nat.Struct.Mol.Biol., 14, 2007
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6MJ6
 | | Crystal structure of the mCD1d/xxx (JJ166) /iNKTCR ternary complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Zajonc, D.M, Bitra, A, Janssens, J. | | 登録日 | 2018-09-20 | | 公開日 | 2019-01-09 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | 4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
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5C0A
 | | 1E6 TCR in complex with HLA-A02 carrying MVW peptide | | 分子名称: | 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ... | | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | | 登録日 | 2015-06-12 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
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5C09
 | | HLA class I histocompatibility antigen | | 分子名称: | 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ... | | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | | 登録日 | 2015-06-12 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.475 Å) | | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
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4WW2
 | | Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8, Beta Chain-TRBV7-8, Antigen-presenting glycoprotein CD1d, and Beta-2-microglobulin | | 分子名称: | (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | | 著者 | Le Nours, J, Praveena, T, Pellicci, D, Gherardin, N.A, Lim, R.T, Besra, G, Keshipeddy, S, Richardson, S.K, Howell, A.R, Gras, S, Godfrey, D.I, Rossjohn, J, Uldrich, A.P. | | 登録日 | 2014-11-10 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
Nat Commun, 7, 2016
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5HHM
 | | Crystal Structure of the JM22 TCR in complex with HLA-A*0201 in complex with M1-F5L | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | | 著者 | Gras, S, Josephs, T.M, Rossjohn, J. | | 登録日 | 2016-01-11 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1BD2
 | | COMPLEX BETWEEN HUMAN T-CELL RECEPTOR B7, VIRAL PEPTIDE (TAX) AND MHC CLASS I MOLECULE HLA-A 0201 | | 分子名称: | BETA-2 MICROGLOBULIN, HLA-A 0201, T CELL RECEPTOR ALPHA, ... | | 著者 | Ding, Y.-H, Smith, K.J, Garboczi, D.N, Utz, U, Biddison, W.E, Wiley, D.C. | | 登録日 | 1998-05-12 | | 公開日 | 1998-08-19 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids.
Immunity, 8, 1998
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4UDU
 | | Crystal structure of staphylococcal enterotoxin E in complex with a T cell receptor | | 分子名称: | ENTEROTOXIN TYPE E, PROTEIN TRBV7-9, T-CELL RECEPTOR BETA-2 CHAIN C REGION, ... | | 著者 | Rodstrom, K.E.J, Regenthal, P, Lindkvist-Petersson, K. | | 登録日 | 2014-12-11 | | 公開日 | 2015-06-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of Staphylococcal Enterotoxin E in Complex with Tcr Defines the Role of Tcr Loop Positioning in Superantigen Recognition.
Plos One, 10, 2015
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2E7L
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5KS9
 | | Bel502-DQ8-glia-alpha1 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bel502 TCR alpha TRAV20*01, Bel502 TCR beta TRBV9*01, ... | | 著者 | Petersen, J, Rossjohn, J, Reid, H.H. | | 登録日 | 2016-07-08 | | 公開日 | 2016-09-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution.
Structure, 24, 2016
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4MXQ
 | | 42F3 TCR pCPC5/H-2Ld Complex | | 分子名称: | 42F3 alpha VmVh chimera, 42F3 beta VmVh chimera, H-2 class I histocompatibility antigen, ... | | 著者 | Birnbaum, M.E, Adams, J.J, Garcia, K.C. | | 登録日 | 2013-09-26 | | 公開日 | 2015-08-19 | | 最終更新日 | 2018-09-26 | | 実験手法 | X-RAY DIFFRACTION (2.596 Å) | | 主引用文献 | Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016
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4Y16
 | | Crystal structure of the mCD1d/NC-aGC/iNKTCR ternary complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zajonc, D.M, Nemcovic, M. | | 登録日 | 2015-02-06 | | 公開日 | 2015-06-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Lipid and Carbohydrate Modifications of alpha-Galactosylceramide Differently Influence Mouse and Human Type I Natural Killer T Cell Activation.
J.Biol.Chem., 290, 2015
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3OWE
 | | Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a High Affinity Mutant Mouse T-cell Receptor Chain | | 分子名称: | Beta-chain, Enterotoxin SEG | | 著者 | Fernandez, M.M, Cho, S, Robinson, H, Mariuzza, R.A, Malchiodi, M.L. | | 登録日 | 2010-09-17 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.
J.Biol.Chem., 286, 2011
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1AO7
 | | COMPLEX BETWEEN HUMAN T-CELL RECEPTOR, VIRAL PEPTIDE (TAX), AND HLA-A 0201 | | 分子名称: | BETA-2 MICROGLOBULIN, ETHYL MERCURY ION, HLA-A 0201, ... | | 著者 | Garboczi, D.N, Ghosh, P, Utz, U, Fan, Q.R, Biddison, W.E, Wiley, D.C. | | 登録日 | 1997-07-21 | | 公開日 | 1997-09-17 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the complex between human T-cell receptor, viral peptide and HLA-A2.
Nature, 384, 1996
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2EYT
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5BRZ
 | | MAGE-A3 reactive TCR in complex with MAGE-A3 in HLA-A1 | | 分子名称: | Beta-2-microglobulin, GLU-VAL-ASP-PRO-ILE-GLY-HIS-LEU-TYR, HLA class I histocompatibility antigen, ... | | 著者 | Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donnellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, LomaX, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K. | | 登録日 | 2015-06-01 | | 公開日 | 2016-03-02 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
Sci Rep, 6, 2016
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7YH1
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8T4Z
 | | T-cell receptor and lipid complex structure | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, ... | | 著者 | Praveena, T, Rossjohn, J. | | 登録日 | 2023-06-12 | | 公開日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (2.691 Å) | | 主引用文献 | T-cell receptor and lipid complex structure
To be published
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2Z31
 | | Crystal structure of immune receptor complex | | 分子名称: | H-2 class II histocompatibility antigen, A-U alpha chain, A-U beta chain precursor, ... | | 著者 | Feng, D, Bond, C.J, Ely, L.K, Garcia, K.C. | | 登録日 | 2007-05-30 | | 公開日 | 2007-10-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'
Nat.Immunol., 8, 2007
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6JFP
 | | Crystal structure of the beta-glucosidase Bgl15 | | 分子名称: | beta-D-glucopyranose, beta-glucosidase 15 | | 著者 | Xie, W, Chen, R. | | 登録日 | 2019-02-11 | | 公開日 | 2020-02-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Engineering of beta-Glucosidase Bgl15 with Simultaneously Enhanced Glucose Tolerance and Thermostability To Improve Its Performance in High-Solid Cellulose Hydrolysis.
J.Agric.Food Chem., 68, 2020
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3TA3
 | | Structure of the mouse CD1d-Glc-DAG-s2-iNKT TCR complex | | 分子名称: | (2S)-1-(alpha-D-glucopyranosyloxy)-3-(hexadecanoyloxy)propan-2-yl (11Z)-octadec-11-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Girardi, E, Yu, E.D, Zajonc, D.M. | | 登録日 | 2011-08-03 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Unique Interplay between Sugar and Lipid in Determining the Antigenic Potency of Bacterial Antigens for NKT Cells.
Plos Biol., 9, 2011
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8GAV
 | | Structure of human NDS.3 Fab in complex with influenza virus neuraminidase from A/Darwin/09/2021 (H3N2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab NDS.3, heavy chain, ... | | 著者 | Tsybovsky, Y, Lederhofer, J, Kwong, P.D, Kanekiyo, M. | | 登録日 | 2023-02-23 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Protective human monoclonal antibodies target conserved sites of vulnerability on the underside of influenza virus neuraminidase.
Immunity, 57, 2024
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3O8X
 | | Recognition of Glycolipid Antigen by iNKT Cell TCR | | 分子名称: | (2S,3R)-3-HYDROXY-2-(TETRADECANOYLAMINO)OCTADECYL ALPHA-D-GALACTOPYRANOSIDURONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zajonc, D.M, Li, Y. | | 登録日 | 2010-08-03 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | The V alpha 14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode.
J.Exp.Med., 207, 2010
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