6PXR
| Anti-TAU BIIB092 FAB with TAU peptide | 分子名称: | Microtubule-associated protein tau, gosuranemab Fab, heavy chain, ... | 著者 | Arndt, J.W, Quan, C. | 登録日 | 2019-07-26 | 公開日 | 2020-07-29 | 最終更新日 | 2021-02-10 | 実験手法 | X-RAY DIFFRACTION (1.556 Å) | 主引用文献 | Characterization of tau binding by gosuranemab. Neurobiol.Dis., 146, 2020
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3BKJ
| Crystal structure of Fab wo2 bound to the n terminal domain of amyloid beta peptide (1-16) | 分子名称: | Amyloid Beta Peptide, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | 著者 | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | 登録日 | 2007-12-06 | 公開日 | 2008-04-15 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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3BAE
| Crystal structure of Fab WO2 bound to the N terminal domain of Amyloid beta peptide (1-28) | 分子名称: | Amyloid Beta Peptide, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | 著者 | Miles, L.A, Wun, K.S, Crespi, G.A, Parker, M.W. | 登録日 | 2007-11-07 | 公開日 | 2008-04-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.593 Å) | 主引用文献 | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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4TQE
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3BKM
| Structure of anti-amyloid-beta Fab WO2 (Form A, P212121) | 分子名称: | SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa, ... | 著者 | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | 登録日 | 2007-12-07 | 公開日 | 2008-04-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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4TPR
| Structure of Tau5 antibody Fab fragment | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diol, CHLORIDE ION, ... | 著者 | Cehlar, O, Skrabana, R, Novak, M. | 登録日 | 2014-06-09 | 公開日 | 2015-07-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of Tau5 antibody Fab fragment To Be Published
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3V4U
| Structure of a monoclonal antibody complexed with its MHC-I antigen | 分子名称: | ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ... | 著者 | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | 登録日 | 2011-12-15 | 公開日 | 2012-07-25 | 最終更新日 | 2012-08-01 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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3UO1
| Structure of a monoclonal antibody complexed with its MHC-I antigen | 分子名称: | ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ... | 著者 | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | 登録日 | 2011-11-16 | 公開日 | 2012-07-25 | 最終更新日 | 2012-08-01 | 実験手法 | X-RAY DIFFRACTION (1.641 Å) | 主引用文献 | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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2IPU
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3V52
| Structure of a monoclonal antibody complexed with its MHC-I antigen | 分子名称: | 1,2-ETHANEDIOL, ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, ... | 著者 | Mage, M.G, Dolan, M.A, Wang, R, Boyd, L.F, Revilleza, M.J, Robinson, H, Natarajan, K, Myers, N.B, Hansen, T.H, Margulies, D.H. | 登録日 | 2011-12-15 | 公開日 | 2012-07-25 | 最終更新日 | 2012-08-01 | 実験手法 | X-RAY DIFFRACTION (1.697 Å) | 主引用文献 | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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2DQU
| Crystal form II: high resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog | 分子名称: | IMMUNOGLOBULIN 6D9, [1-(3-DIMETHYLAMINO-PROPYL)-3-ETHYL-UREIDO]-[4-(2,2,2-TRIFLUORO-ACETYLAMINO)-BENZYL]PHOSPHINIC ACID-2-(2,2-DIHYDRO-ACETYLAMINO)-3-HYDROXY-1-(4-NITROPHENYL)-PROPYL ESTER | 著者 | Kristensen, O, Vassylyev, D.G, Tanaka, F, Ito, N, Morikawa, K, Fujii, I. | 登録日 | 2006-05-30 | 公開日 | 2006-06-20 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis J.Mol.Biol., 369, 2007
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3UYR
| Structure of a monoclonal antibody complexed with its MHC-I antigen | 分子名称: | 1,2-ETHANEDIOL, H-2 class I histocompatibility antigen, L-D alpha chain, ... | 著者 | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | 登録日 | 2011-12-06 | 公開日 | 2012-07-25 | 最終更新日 | 2012-08-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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1ZEA
| Structure of the anti-cholera toxin antibody Fab fragment TE33 in complex with a D-peptide | 分子名称: | CITRIC ACID, monoclonal anti-cholera toxin IGG1 KAPPA antibody, H chain, ... | 著者 | Scheerer, P, Krauss, N, Wessner, H, Scholz, C, Otte, L, Seifert, M, Kramer, A, Schneider-Mergener, J, Hoehne, W. | 登録日 | 2005-04-18 | 公開日 | 2006-04-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structure of an anti-cholera toxin antibody Fab in complex with an epitope-derived D-peptide: a case of polyspecific recognition. J.Mol.Recognit., 20, 2007
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1PZ5
| Structural basis of peptide-carbohydrate mimicry in an antibody combining site | 分子名称: | Heavy chain of Fab (SYA/J6), Light chain of Fab (SYA/J6), Octapeptide (MDWNMHAA) | 著者 | Vyas, N.K, Vyas, M.N, Chervenak, M.C, Bundle, D.R, Pinto, B.M, Quiocho, F.A. | 登録日 | 2003-07-09 | 公開日 | 2003-11-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis of peptide-carbohydrate mimicry in an antibody combining site. Proc.Natl.Acad.Sci.USA, 100, 2003
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2DQT
| High resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog | 分子名称: | IMMUNOGLOBULIN 6D9, [1-(3-DIMETHYLAMINO-PROPYL)-3-ETHYL-UREIDO]-[4-(2,2,2-TRIFLUORO-ACETYLAMINO)-BENZYL]PHOSPHINIC ACID-2-(2,2-DIHYDRO-ACETYLAMINO)-3-HYDROXY-1-(4-NITROPHENYL)-PROPYL ESTER | 著者 | Kristensen, O, Vassylyev, D.G, Tanaka, F, Ito, N, Morikawa, K, Fujii, I. | 登録日 | 2006-05-30 | 公開日 | 2006-06-20 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis J.Mol.Biol., 369, 2007
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1T2Q
| The Crystal Structure of an NNA7 Fab that recognizes an N-type blood group antigen | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Fab NNA7 Heavy Chain, Fab NNA7 Light Chain, ... | 著者 | Xie, K, Song, S.C, Spitalnik, S.L, Wedekind, J.E. | 登録日 | 2004-04-22 | 公開日 | 2005-06-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Crystal Structure and Mutational Analysis of an Antibody that Recognizes an N-type Blood Group Antigen To be Published
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1F3D
| CATALYTIC ANTIBODY 4B2 IN COMPLEX WITH ITS AMIDINIUM HAPTEN. | 分子名称: | 2-(4-AMINOBENZYLAMINO)-3,4,5,6-TETRAHYDROPYRIDINIUM, CATALYTIC ANTIBODY 4B2, SULFATE ION | 著者 | Golinelli-Pimpaneau, B, Goncalves, O, Dintinger, T, Blanchard, D, Knossow, M, Tellier, C. | 登録日 | 2000-06-02 | 公開日 | 2000-09-13 | 最終更新日 | 2012-07-04 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structural evidence for a programmed general base in the active site of a catalytic antibody. Proc.Natl.Acad.Sci.USA, 97, 2000
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2OK0
| Fab ED10-DNA complex | 分子名称: | 5'-D(*TP*C)-3', Fab ED10 heavy chain, Fab ED10 light chain | 著者 | Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G. | 登録日 | 2007-01-15 | 公開日 | 2007-06-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Specific recognition of a DNA immunogen by its elicited antibody J.Mol.Biol., 370, 2007
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3BKC
| Crystal structure of anti-amyloid beta FAB WO2 (P21, FormB) | 分子名称: | SODIUM ION, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | 著者 | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | 登録日 | 2007-12-06 | 公開日 | 2008-04-15 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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4P3D
| MT1-MMP:Fab complex (Form II) | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Rozenberg, H, Udi, Y, Sagi, I. | 登録日 | 2014-03-07 | 公開日 | 2014-12-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | 主引用文献 | Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody. Structure, 23, 2015
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3EYS
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1NBV
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2IQA
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2IPT
| PFA1 Fab Fragment | 分子名称: | ACETAMIDE, IgG2a Fab fragment Heavy Chain, IgG2a Fab fragment Light Chain Kappa | 著者 | Gardberg, A.S, Dealwis, C. | 登録日 | 2006-10-12 | 公開日 | 2007-10-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular basis for passive immunotherapy of Alzheimer's disease Proc.Natl.Acad.Sci.Usa, 104, 2007
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1LO0
| Catalytic Retro-Diels-Alderase Transition State Analogue Complex | 分子名称: | 3-{[(9-CYANO-9,10-DIHYDRO-10-METHYLACRIDIN-9-YL)CARBONYL]AMINO}PROPANOIC ACID, If kappa light chain, Ig gamma 2a heavy chain | 著者 | Hugot, M, Reymond, J.L, Baumann, U. | 登録日 | 2002-05-05 | 公開日 | 2002-06-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A structural basis for the activity of retro-Diels-Alder catalytic antibodies: evidence for a catalytic aromatic residue. Proc.Natl.Acad.Sci.USA, 99, 2002
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