7SWX
| |
7TLA
| |
7XO5
| SARS-CoV-2 Omicron BA.1 Variant Spike Trimer with one mouse ACE2 Bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | 登録日 | 2022-05-01 | 公開日 | 2022-06-15 | 最終更新日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins. Cell Res., 32, 2022
|
|
7CYV
| Crystal structure of FD20, a neutralizing single-chain variable fragment (scFv) in complex with SARS-CoV-2 Spike receptor-binding domain (RBD) | 分子名称: | Spike protein S1, The heavy chain variable region of the scFv FD20,The light chain variable region of the scFv FD20, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Li, Y, Li, T, Lai, Y, Cai, H, Yao, H, Li, D. | 登録日 | 2020-09-04 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | 主引用文献 | Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody. Embo Mol Med, 13, 2021
|
|
7YJ3
| Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with human ACE2 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | 著者 | Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2022-07-19 | 公開日 | 2023-07-19 | 最終更新日 | 2023-08-02 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants. Nat Commun, 14, 2023
|
|
7K9K
| |
7N1U
| Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Cai, Y.F, Xiao, T.S, Rawson, S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Volloch, S.R, Chen, B. | 登録日 | 2021-05-28 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants. Science, 373, 2021
|
|
7PS5
| Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-47 Fab | 分子名称: | Beta-47 Fab heavy chain, Beta-47 Fab light chain, Spike protein S1, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2021-09-22 | 公開日 | 2021-12-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
|
|
7SY8
| Cryo-EM structure of the SARS-CoV-2 D614G,N501Y,E484K,K417T mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Kim, A, Li, W, Dimitrov, D.S, Subramaniam, S. | 登録日 | 2021-11-24 | 公開日 | 2021-12-29 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding. Cell Rep, 37, 2021
|
|
8DLU
| Cryo-EM structure of SARS-CoV-2 Epsilon (B.1.429) spike protein in complex with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Zhu, X, Mannar, D, Saville, J.W, Srivastava, S.S, Berezuk, A.M, Zhou, S, Tuttle, K.S, Subramaniam, S. | 登録日 | 2022-07-08 | 公開日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization. Nat Commun, 13, 2022
|
|
7NXC
| |
7E88
| |
8WOY
| Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 RBD in complex with rabbit ACE2 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | 著者 | Li, L.J, Shi, K.Y, Yu, G.H, Gao, G.F. | 登録日 | 2023-10-08 | 公開日 | 2023-12-13 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency. Mbio, 15, 2024
|
|
7MM0
| Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B1-182.1 Fab heavy chain, ... | 著者 | Zhou, T, Tsybovsky, T, Kwong, P.D. | 登録日 | 2021-04-29 | 公開日 | 2021-07-28 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants. Science, 373, 2021
|
|
7CH4
| |
7ZF3
| SARS-CoV-2 Omicron RBD in complex with Omi-3 and EY6A Fabs | 分子名称: | EY6A heavy chain, EY6A light chain, GLYCEROL, ... | 著者 | Zhou, D, Huo, J, Ren, J, Stuart, D.I. | 登録日 | 2022-04-01 | 公開日 | 2022-06-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Potent cross-reactive antibodies following Omicron breakthrough in vaccinees. Cell, 185, 2022
|
|
7MW3
| |
7F12
| A SARS-CoV-2 neutralizing antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody, Spike protein S1 | 著者 | Zhang, G, Li, X, Guo, Y, Wang, Y, Yuan, S. | 登録日 | 2021-06-07 | 公開日 | 2022-06-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | A SARS-CoV-2 neutralizing
antibody To Be Published
|
|
7MKM
| |
8EQF
| |
8F2J
| |
8CBE
| SARS-CoV-2 Delta-RBD complexed with BA.4/5-2 and Beta-49 Fabs | 分子名称: | BA.4/5-2 heavy chain, BA.4/5-2 light chain, Beta-49 heavy chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2023-01-25 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | 主引用文献 | Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection. Nat Commun, 15, 2024
|
|
7TF5
| Cryo-EM structure of SARS-CoV-2 Kappa (B.1.617.1) spike protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Zhu, X, Saville, J.W, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Zhou, S, Tuttle, K.S, Subramaniam, S. | 登録日 | 2022-01-06 | 公開日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants. Nat Commun, 13, 2022
|
|
7E8C
| SARS-CoV-2 S-6P in complex with 9 Fabs | 分子名称: | 368-2 H, 368-2 L, 604 H, ... | 著者 | Du, S, Xiao, J, Zhang, Z. | 登録日 | 2021-03-01 | 公開日 | 2021-06-09 | 最終更新日 | 2021-07-14 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines. Cell Res., 31, 2021
|
|
7TOV
| |