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PDB: 465 件
6D08
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Crystal structure of an engineered bump-hole complex of mutant human chromobox homolog 1 (CBX1) with H3K9bn peptide
分子名称: Chromobox protein homolog 1, GLYCEROL, Histone H3.1, ...
著者Arora, S, Horne, W.S, Islam, K.
登録日2018-04-10
公開日2019-04-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Engineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein-Protein Interactions.
J.Am.Chem.Soc., 141, 2019
8IIZ
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BU of 8iiz by Molmil
Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K27ac peptide
分子名称: GLYCEROL, Histone H3.1, Maltodextrin-binding protein,YEATS domain-containing protein 4, ...
著者Kikuchi, M, Umehara, T.
登録日2023-02-24
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
6IIT
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BU of 6iit by Molmil
Complex structure of the HRP3 PWWP domain with both a 16-bp TA-rich DNA and an H3K36me2-containing histone peptide
分子名称: 16-bp TA-rich DNA, H3K36me2-containing histone peptide, Hepatoma-derived growth factor-related protein 3
著者Wang, Z, Tian, W.
登録日2018-10-07
公開日2019-04-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Complex structure of the HRP3 PWWP domain with both a 16-bp TA-rich DNA and a H3K36me2-containing histone peptide
Nucleic Acids Res., 2019
5FB1
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BU of 5fb1 by Molmil
Crystal Structure of a PHD finger bound to histone H3 K9me3 peptide
分子名称: MALONATE ION, Nuclear autoantigen Sp-100, Peptide from Histone H3, ...
著者Li, H, Zhang, X.
登録日2015-12-13
公開日2016-05-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Multifaceted Histone H3 Methylation and Phosphorylation Readout by the Plant Homeodomain Finger of Human Nuclear Antigen Sp100C
J.Biol.Chem., 291, 2016
2CNX
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BU of 2cnx by Molmil
WDR5 and Histone H3 Lysine 4 dimethyl complex at 2.1 angstrom
分子名称: HISTONE H3 DIMETHYL-LYSINE 4, WD-REPEAT PROTEIN 5
著者Ruthenburg, A.J, Wang, W, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-25
公開日2006-07-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Histone H3 Recognition and Presentation by the Wdr5 Module of the Mll1 Complex
Nat.Struct.Mol.Biol., 13, 2006
5IQL
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BU of 5iql by Molmil
Crystal structure of YEATS2 YEATS bound to H3K27cr peptide
分子名称: Histone H3.1, YEATS domain-containing protein 2
著者Li, H, Zhao, D, Guan, H.
登録日2016-03-11
公開日2016-07-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献YEATS2 is a selective histone crotonylation reader.
Cell Res., 26, 2016
6D07
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BU of 6d07 by Molmil
Crystal structure of the complex between human chromobox homolog 1 (CBX1) and H3K9me3 peptide
分子名称: Chromobox protein homolog 1, GLYCEROL, Histone H3.1
著者Arora, S, Horne, W.S, Islam, K.
登録日2018-04-10
公開日2019-04-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Engineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein-Protein Interactions.
J.Am.Chem.Soc., 141, 2019
7MJU
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BU of 7mju by Molmil
Crystal structure of human AF10 PZP bound to histone H3 tail
分子名称: Histone H3.1,Protein AF-10, ZINC ION
著者Klein, B.J, Kutateladze, T.G.
登録日2021-04-20
公開日2021-08-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations.
Nat Commun, 12, 2021
5C13
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Crystal Structure of TAF3 PHD finger bound to histone H3C4me3 peptide
分子名称: H3 peptide, Transcription initiation factor TFIID subunit 3, ZINC ION
著者Li, H, Huang, J.
登録日2015-06-12
公開日2015-11-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Crystal Structure of Jarid1a PHD finger bound to histone H3C4me3 peptide
Nat Commun, 2015
5XTZ
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Crystal structure of GAS41 YEATS bound to H3K27ac peptide
分子名称: ACETATE ION, THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, YEATS domain-containing protein 4
著者Li, H.T, Zhao, D.
登録日2017-06-21
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity.
Cell Discov, 4, 2018
2OT7
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BU of 2ot7 by Molmil
Crystal structure of JMJD2A complexed with histone H3 peptide monomethylated at Lys9
分子名称: JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ...
著者Kavanagh, K.L, Ng, S.S, Pilka, E, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2007-02-07
公開日2007-03-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.135 Å)
主引用文献Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature, 448, 2007
5OY3
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The structural basis of the histone demethylase KDM6B histone 3 lysine 27 specificity
分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, FE (III) ION, ...
著者Jones, S.E, Olsen, L, Gajhede, M.
登録日2017-09-07
公開日2017-09-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.136 Å)
主引用文献Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity.
Biochemistry, 57, 2018
8IIY
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BU of 8iiy by Molmil
Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K14ac peptide
分子名称: GLYCEROL, Histone H3.1, Maltodextrin-binding protein,YEATS domain-containing protein 4, ...
著者Kikuchi, M, Umehara, T.
登録日2023-02-24
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
3U4S
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BU of 3u4s by Molmil
Histone Lysine demethylase JMJD2A in complex with T11C peptide substrate crosslinked to N-oxalyl-D-cysteine
分子名称: HISTONE 3 TAIL ANALOG (T11C Peptide), Lysine-specific demethylase 4A, N-(carboxycarbonyl)-D-cysteine, ...
著者Ma, J, McDonough, M.A, Schofield, C.J.
登録日2011-10-10
公開日2012-02-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases.
Angew.Chem.Int.Ed.Engl., 51, 2012
6JOU
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BU of 6jou by Molmil
Crystal structure of the human nucleosome containing H2A.Z.1 S42R
分子名称: DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ...
著者Horikoshi, N, Sato, K, Mizukami, Y, Kurumizaka, H.
登録日2019-03-23
公開日2020-03-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structure-based design of an H2A.Z.1 mutant stabilizing a nucleosome in vitro and in vivo.
Biochem.Biophys.Res.Commun., 515, 2019
8Q3E
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BU of 8q3e by Molmil
High Resolution Structure of Nucleosome Core with Bound Foamy Virus GAG Peptide
分子名称: DNA (145-MER), GLY-GLY-TYR-ASN-LEU-ARG-PRO-ARG-THR-TYR-GLN-PRO-GLN-ARG-TYR-GLY-GLY-GLY, Histone H2A type 1-B/E, ...
著者De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A.
登録日2023-08-04
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.174 Å)
主引用文献Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
3U31
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BU of 3u31 by Molmil
Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine
分子名称: GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Transcriptional regulatory protein sir2 homologue, ...
著者Zhou, Y, Hao, Q.
登録日2011-10-04
公開日2011-11-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Plasmodium falciparum Sir2A Preferentially Hydrolyzes Medium and Long Chain Fatty Acyl Lysine
Acs Chem.Biol., 2011
3ZG6
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BU of 3zg6 by Molmil
The novel de-long chain fatty acid function of human sirt6
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, GLYCEROL, NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-6, ...
著者Wang, Y, Hao, Q.
登録日2012-12-15
公開日2013-04-03
最終更新日2013-04-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Sirt6 Regulates Tnf-Alpha Secretion Through Hydrolysis of Long-Chain Fatty Acyl Lysine
Nature, 496, 2013
4TN7
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BU of 4tn7 by Molmil
Crystal structure of mouse KDM2A-H3K36ME-NO complex
分子名称: FE (III) ION, Lysine-specific demethylase 2A, NITRIC OXIDE, ...
著者Cheng, Z.
登録日2014-06-03
公開日2015-05-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
5AV9
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BU of 5av9 by Molmil
human nucleosome core particle
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S.
登録日2015-06-12
公開日2015-12-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
6LS6
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BU of 6ls6 by Molmil
Crystal Structure of YEATS domain of AF9 in complex with H3K9bz peptide
分子名称: 2, Protein AF-9
著者Li, H.T, Ren, X.L.
登録日2020-01-17
公開日2020-11-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Histone benzoylation serves as an epigenetic mark for DPF and YEATS family proteins.
Nucleic Acids Res., 49, 2021
5AV8
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human nucleosome core particle
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S.
登録日2015-06-12
公開日2015-12-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015
5B31
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The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.1.
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H.
登録日2016-02-08
公開日2016-08-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A.
Open Biology, 6, 2016
6K1K
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BU of 6k1k by Molmil
Human nucleosome core particle with H2A.X S139E variant
分子名称: CHLORIDE ION, DNA (145-MER), Histone H2AX, ...
著者Sharma, D, De Falco, L, Davey, C.A.
登録日2019-05-10
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Nat Commun, 10, 2019
5AV6
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human nucleosome core particle
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S.
登録日2015-06-12
公開日2015-12-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation
Sci Rep, 5, 2015

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