7E8D
 
 | | NSD2 E1099K mutant bound to nucleosome | | 分子名称: | DNA (185-MER), Histone H2A type 1, Histone H2B type 1-J, ... | | 著者 | Sengoku, T, Sato, K, Nishizawa, T, Nureki, O, Ogata, K. | | 登録日 | 2021-03-01 | | 公開日 | 2021-11-10 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2.
Nat Commun, 12, 2021
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6M4G
 | | Structural mechanism of nucleosome dynamics governed by human histone variants H2A.B and H2A.Z.2.2 | | 分子名称: | DNA (93-MER), Histone H2A-Bbd type 2/3, Histone H2B type 2-E, ... | | 著者 | Zhou, M, Dai, L.C, Li, C.M, Shi, L.X, Huang, Y, Guo, Z.Q. | | 登録日 | 2020-03-06 | | 公開日 | 2020-09-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2A.Z.2.2.
Embo J., 40, 2021
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3WKJ
 | | The nucleosome containing human TSH2B | | 分子名称: | CHLORIDE ION, DNA (145-MER), Histone H2A type 1-B/E, ... | | 著者 | Urahama, T, Horikoshi, N, Osakabe, A, Tachiwana, H, Kurumizaka, H. | | 登録日 | 2013-10-22 | | 公開日 | 2014-04-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of human nucleosome containing the testis-specific histone variant TSH2B.
Acta Crystallogr.,Sect.F, 70, 2014
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4A0J
 | | Crystal structure of Survivin bound to the phosphorylated N-terminal tail of histone H3 | | 分子名称: | BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, HISTONE H3 PEPTIDE, ZINC ION | | 著者 | Jeyaprakash, A.A, Basquin, C, Jayachandran, U, Conti, E. | | 登録日 | 2011-09-09 | | 公開日 | 2011-11-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.803 Å) | | 主引用文献 | Structural Basis for the Recognition of Phosphorylated Histone H3 by the Survivin Subunit of the Chromosomal Passenger Complex.
Structure, 19, 2011
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5C11
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3X1S
 | | Crystal structure of the nucleosome core particle | | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | | 著者 | Sivaraman, P, Kumarevel, T.S. | | 登録日 | 2014-11-27 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | | 主引用文献 | Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming
Biochem.Biophys.Res.Commun., 464, 2015
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5HJD
 | | AF9 YEATS in complex with histone H3 Crotonylation at K18 | | 分子名称: | COPPER (II) ION, Protein AF-9, SULFATE ION, ... | | 著者 | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | | 登録日 | 2016-01-13 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | | 主引用文献 | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain.
Mol.Cell, 62, 2016
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3X1T
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8GUI
 | | Bre1-nucleosome complex (Model I) | | 分子名称: | DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ... | | 著者 | Onishi, S, Hamada, K, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T. | | 登録日 | 2022-09-12 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | | 主引用文献 | Structure of the human Bre1 complex bound to the nucleosome.
Nat Commun, 15, 2024
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5XF5
 | | Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,S-configuration) | | 分子名称: | (1S,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ... | | 著者 | Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. | | 登録日 | 2017-04-07 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
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5GT0
 | | Crystal structure of nucleosome complex with human testis-specific histone variants, Th2a | | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-A, ... | | 著者 | Kumarevel, T, Sivaraman, P. | | 登録日 | 2016-08-18 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b
Biophys. Chem., 221, 2017
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7XVM
 | | Crystal Structure of Nucleosome-H5 Linker Histone Assembly (sticky-169a DNA fragment) | | 分子名称: | CALCIUM ION, CHLORIDE ION, DNA (169-MER), ... | | 著者 | Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. | | 登録日 | 2022-05-24 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment)
To Be Published
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7K61
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8EVH
 | | CX3CR1 nucleosome and wild type PU.1 complex | | 分子名称: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Lian, T, Guan, R, Bai, Y. | | 登録日 | 2022-10-20 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
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6K1J
 | | Human nucleosome core particle with H2A.X variant | | 分子名称: | CHLORIDE ION, DNA (145-MER), Histone H2AX, ... | | 著者 | Sharma, D, De Falco, L, Davey, C.A. | | 登録日 | 2019-05-10 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Nat Commun, 10, 2019
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7COW
 | | 353 bp di-nucleosome harboring cohesive DNA termini with linker histone H1.0 | | 分子名称: | CALCIUM ION, CHLORIDE ION, DNA (353-MER), ... | | 著者 | Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. | | 登録日 | 2020-08-05 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
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5XF4
 | | Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (S,S-configuration) | | 分子名称: | (1S,2S)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ... | | 著者 | Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. | | 登録日 | 2017-04-07 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
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8XBW
 | | The cryo-EM structure of the RAD51 N-terminal lobe domain bound to the histone H4 tail of the nucleosome | | 分子名称: | DNA (5'-D(P*AP*CP*CP*GP*CP*TP*TP*AP*AP*AP*CP*GP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*CP*GP*TP*TP*TP*AP*AP*GP*CP*GP*GP*T)-3'), DNA repair protein RAD51 homolog 1, ... | | 著者 | Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-12-07 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
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3AZM
 | | Crystal Structure of Human Nucleosome Core Particle Containing H4K79Q mutation | | 分子名称: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | | 著者 | Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2011-05-25 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
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3AZJ
 | | Crystal Structure of Human Nucleosome Core Particle Containing H4K44Q mutation | | 分子名称: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | | 著者 | Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2011-05-25 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
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3AYW
 | | Crystal Structure of Human Nucleosome Core Particle Containing H3K56Q mutation | | 分子名称: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | | 著者 | Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2011-05-19 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
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5CPI
 | | Nucleosome containing unmethylated Sat2R DNA | | 分子名称: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Osakabe, A, Arimura, Y, Adachi, F, Maehara, K, Ohkawa, Y, Kurumizaka, H. | | 登録日 | 2015-07-21 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.902 Å) | | 主引用文献 | Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA.
Open Biology, 5, 2015
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7LYA
 | | Cryo-EM structure of the human nucleosome core particle with linked histone proteins H2A and H2B | | 分子名称: | DNA (146-MER), DNA (147-MER), Histone H2A type 1-B/E, ... | | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G. | | 登録日 | 2021-03-06 | | 公開日 | 2021-07-28 | | 最終更新日 | 2021-09-01 | | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | | 主引用文献 | Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation.
Nature, 596, 2021
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5GT3
 | | Crystal structure of nucleosome particle in the presence of human testis-specific histone variant, hTh2b | | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-D, ... | | 著者 | Kumarevel, T, Sivaraman, P. | | 登録日 | 2016-08-18 | | 公開日 | 2017-02-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b
Biophys. Chem., 221, 2017
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3X1V
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