7JZV
| Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome | 分子名称: | BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ... | 著者 | Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E. | 登録日 | 2020-09-02 | 公開日 | 2021-02-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1. Nat.Struct.Mol.Biol., 28, 2021
|
|
7C0M
| Human cGAS-nucleosome complex | 分子名称: | Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1-B/E, ... | 著者 | Kujirai, T, Zierhut, C, Takizawa, Y, Kim, R, Negishi, L, Uruma, N, Hirai, S, Funabiki, H, Kurumizaka, H. | 登録日 | 2020-05-01 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis for the inhibition of cGAS by nucleosomes. Science, 370, 2020
|
|
6BUZ
| Cryo-EM structure of CENP-A nucleosome in complex with kinetochore protein CENP-N | 分子名称: | DNA (147-MER), Histone H2A, Histone H2B, ... | 著者 | Chittori, S, Hong, J, Kelly, A.E, Bai, Y, Subramaniam, S. | 登録日 | 2017-12-11 | 公開日 | 2017-12-20 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N. Science, 359, 2018
|
|
7V96
| Telomeric Dinucleosome | 分子名称: | DNA (275-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | 著者 | Soman, A. | 登録日 | 2021-08-24 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Columnar structure of human telomeric chromatin. Nature, 609, 2022
|
|
7X58
| Cryo-EM structure of human subnucleosome (open form) | 分子名称: | Histone H3.1, Histone H4, Widom601 DNA FW (145-MER), ... | 著者 | Nozawa, K, Takizawa, Y, Kurumizaka, H. | 登録日 | 2022-03-04 | 公開日 | 2022-11-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Cryo-electron microscopy structure of the H3-H4 octasome: A nucleosome-like particle without histones H2A and H2B. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7W9V
| Cryo-EM structure of nucleosome in complex with p300 acetyltransferase catalytic core (complex I) | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Hatazawa, S, Liu, J, Takizawa, Y, Zandian, M, Negishi, L, Kutateladze, T.G, Kurumizaka, H. | 登録日 | 2021-12-10 | 公開日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.95 Å) | 主引用文献 | Structural basis for binding diversity of acetyltransferase p300 to the nucleosome. Iscience, 25, 2022
|
|
7Y00
| Cryo-EM structure of the nucleosome containing 169 base-pair DNA with a p53 target sequence | 分子名称: | DNA (169-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Nishimura, M, Nozawa, K, Takizawa, Y, Kurumizaka, H. | 登録日 | 2022-06-03 | 公開日 | 2022-10-19 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Structural basis for p53 binding to its nucleosomal target DNA sequence. Pnas Nexus, 1, 2022
|
|
7XZY
| Cryo-EM structure of the nucleosome containing 193 base-pair DNA with a p53 target sequence | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Nishimura, M, Nozawa, K, Takizawa, Y, Kurumizaka, H. | 登録日 | 2022-06-03 | 公開日 | 2022-10-19 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | Structural basis for p53 binding to its nucleosomal target DNA sequence. Pnas Nexus, 1, 2022
|
|
6C0W
| Cryo-EM structure of human kinetochore protein CENP-N with the centromeric nucleosome containing CENP-A | 分子名称: | 147 mer DNA, Centromere protein N, Histone H2A, ... | 著者 | Zhou, K, Pentakota, S, Vetter, I.R, Morgan, G.P, Petrovic, A, Musacchio, A, Luger, K. | 登録日 | 2018-01-02 | 公開日 | 2018-01-17 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Decoding the centromeric nucleosome through CENP-N. Elife, 6, 2017
|
|
6T7C
| Structure of two copies of human Sox11 transcription factor in complex with a nucleosome | 分子名称: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | 著者 | Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. | 登録日 | 2019-10-21 | 公開日 | 2020-04-29 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature, 580, 2020
|
|
7U53
| |
6R93
| Cryo-EM structure of NCP-6-4PP | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
|
|
7WBX
| RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-3) of the nucleosome | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. | 登録日 | 2021-12-17 | 公開日 | 2023-07-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome. J.Mol.Biol., 435, 2023
|
|
7PF3
| |
7PF4
| |
7PF6
| |
8SNA
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c with backside ubiquitin (UbcH5c chemically conjugated to histone H2A) (class 2) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
|
|
4YM5
| Crystal structure of the human nucleosome containing 6-4PP (inside) | 分子名称: | 144 mer-DNA, 144-mer DNA, Histone H2A type 1-B/E, ... | 著者 | Osakabe, A, Tachiwana, H, Kagawa, W, Horikoshi, N, Matsumoto, S, Hasegawa, M, Matsumoto, N, Toga, T, Yamamoto, J, Hanaoka, F, Thoma, N.H, Sugasawa, K, Iwai, S, Kurumizaka, H. | 登録日 | 2015-03-06 | 公開日 | 2015-12-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (4.005 Å) | 主引用文献 | Structural basis of pyrimidine-pyrimidone (6-4) photoproduct recognition by UV-DDB in the nucleosome Sci Rep, 5, 2015
|
|
7XZZ
| Cryo-EM structure of the nucleosome in complex with p53 | 分子名称: | Cellular tumor antigen p53, DNA (169-MER), Histone H2A type 1-B/E, ... | 著者 | Nishimura, M, Nozawa, K, Takizawa, Y, Kurumizaka, H. | 登録日 | 2022-06-03 | 公開日 | 2022-10-12 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (4.07 Å) | 主引用文献 | Structural basis for p53 binding to its nucleosomal target DNA sequence. Pnas Nexus, 1, 2022
|
|
6J4Z
| RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome | 分子名称: | DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ... | 著者 | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | 登録日 | 2019-01-10 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors. Science, 363, 2019
|
|
7WBV
| RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-4) of the nucleosome | 分子名称: | DNA (159-MER), DNA (198-MER), DNA-directed RNA polymerase subunit, ... | 著者 | Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. | 登録日 | 2021-12-17 | 公開日 | 2023-07-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome. J.Mol.Biol., 435, 2023
|
|
8EVJ
| CX3CR1 nucleosome bound PU.1 and C/EBPa | 分子名称: | DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | 著者 | Guan, R, Bai, Y, Lian, T. | 登録日 | 2022-10-20 | 公開日 | 2023-11-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha. Nat.Struct.Mol.Biol., 31, 2024
|
|
6R91
| Cryo-EM structure of NCP_THF2(-3)-UV-DDB | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ... | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | 登録日 | 2019-04-02 | 公開日 | 2019-06-12 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
|
|
8RBX
| Structure of Integrator-PP2A bound to a paused RNA polymerase II-DSIF-NELF-nucleosome complex | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. | 登録日 | 2023-12-05 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629, 2024
|
|
6Y5D
| Structure of human cGAS (K394E) bound to the nucleosome | 分子名称: | Cyclic GMP-AMP synthase, DNA (153-MER), Histone H2A type 2-A, ... | 著者 | Pathare, G.R, Cavadini, S, Kempf, G, Thoma, N.H. | 登録日 | 2020-02-25 | 公開日 | 2020-09-23 | 最終更新日 | 2020-12-09 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural mechanism of cGAS inhibition by the nucleosome. Nature, 587, 2020
|
|