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PDB: 63 件
6MWD
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BU of 6mwd by Molmil
NavAb Voltage-gated Sodium Channel, residues 1-239 with mutation T206S
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ACETATE ION, ...
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-29
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.327 Å)
主引用文献Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb.
J. Gen. Physiol., 151, 2019
6MWA
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BU of 6mwa by Molmil
NavAb Voltage-gated Sodium Channel, residues 1-239
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein, ...
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-29
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb.
J. Gen. Physiol., 151, 2019
6MWG
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BU of 6mwg by Molmil
NavAb Voltage-gated Sodium Channel, residues 1-239, with mutation T206V
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ACETATE ION, ...
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-29
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb.
J. Gen. Physiol., 151, 2019
6C1M
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BU of 6c1m by Molmil
NavAb NormoPP mutant
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-METHYLGUANIDINE, CHAPSO, ...
著者Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M.
登録日2018-01-04
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.518 Å)
主引用文献Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
8DIV
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BU of 8div by Molmil
Crystal structure of NavAb I22V as a basis for the human Nav1.7 Inherited Erythromelalgia I136V mutation
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein, ...
著者Wisedchaisri, G, Gamal El-Din, T.M, Powell, N.M, Zheng, N, Catterall, W.A.
登録日2022-06-29
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7.
J.Gen.Physiol., 155, 2023
6MWB
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BU of 6mwb by Molmil
NavAb Voltage-gated Sodium Channel, residues 1-239 with mutation T206A
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein, ...
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-29
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb.
J. Gen. Physiol., 151, 2019
8DJ0
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BU of 8dj0 by Molmil
Crystal structure of NavAb L123T as a basis for the human Nav1.7 Inherited Erythromelalgia I848T mutation
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein
著者Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A.
登録日2022-06-29
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na V 1.7.
Proc.Natl.Acad.Sci.USA, 120, 2023
5KLB
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BU of 5klb by Molmil
Crystal structure of the CavAb voltage-gated calcium channel(wild-type, 2.7A)
分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, ...
著者Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A.
登録日2016-06-23
公開日2016-08-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
8H9W
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BU of 8h9w by Molmil
Crystal structure of voltage-gated sodium channel NavAb N49K mutant in calcium ion condition
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, CHAPSO, ...
著者Irie, K.
登録日2022-10-25
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel.
Nat Commun, 14, 2023
6C1K
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BU of 6c1k by Molmil
HypoPP mutant with ligand1
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GUANIDINE, Ion transport protein, ...
著者Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M.
登録日2018-01-04
公開日2018-05-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
3RVY
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BU of 3rvy by Molmil
Crystal structure of the NavAb voltage-gated sodium channel (Ile217Cys, 2.7 A)
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein
著者Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A.
登録日2011-05-06
公開日2011-07-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
6P6X
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BU of 6p6x by Molmil
Crystal structure of voltage-gated sodium channel NavAb G94C/Q150C mutant in the activated state
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein
著者Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-Din, T.M, Wang, L, Zheng, N, Catterall, W.A.
登録日2019-06-04
公開日2019-08-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.
Cell, 178, 2019
8DIZ
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BU of 8diz by Molmil
Crystal structure of NavAb I119T as a basis for the human Nav1.7 Inherited Erythromelalgia I234T mutation
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein
著者Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A.
登録日2022-06-29
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na V 1.7.
Proc.Natl.Acad.Sci.USA, 120, 2023
4MS2
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BU of 4ms2 by Molmil
Structural basis of Ca2+ selectivity of a voltage-gated calcium channel
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein
著者Tang, L, Gamal El-Din, T.M, Payandeh, J, Martinez, G.Q, Heard, T.M, Scheuer, T, Zheng, N, Catterall, W.A.
登録日2013-09-18
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature, 505, 2014
3RVZ
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BU of 3rvz by Molmil
Crystal structure of the NavAb voltage-gated sodium channel (Ile217Cys, 2.8 A)
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein
著者Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A.
登録日2011-05-06
公開日2011-07-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
5YUA
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BU of 5yua by Molmil
Crystal structure of voltage-gated sodium channel NavAb in high-pH condition
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, CHAPSO, ...
著者Irie, K, Shimomura, T, Fujiyoshi, Y.
登録日2017-11-21
公開日2017-12-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.80085564 Å)
主引用文献Structural insight on the voltage dependence of prokaryotic voltage gated sodium channel NavAb.
FEBS Lett., 2017
6KE5
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BU of 6ke5 by Molmil
Structure of CavAb in complex with Diltiazem and Amlodipine
分子名称: CALCIUM ION, Ion transport protein, SN-GLYCEROL-3-PHOSPHATE, ...
著者Tang, L.
登録日2019-07-03
公開日2019-10-23
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+Channel.
Mol.Pharmacol., 96, 2019
5VB8
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BU of 5vb8 by Molmil
Crystal structure of the NavAb voltage-gated sodium channel in an open state
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, SODIUM ION, ...
著者Lenaeus, M.J, Catterall, W.A.
登録日2017-03-28
公開日2017-04-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structures of closed and open states of a voltage-gated sodium channel.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8DIY
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BU of 8diy by Molmil
Crystal structure of NavAb L101S as a basis for the human Nav1.7 Inherited Erythromelalgia F216S mutation
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein
著者Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A.
登録日2022-06-29
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7.
J.Gen.Physiol., 155, 2023
6C1E
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BU of 6c1e by Molmil
NavAb NormoPP mutant
分子名称: (3ALPHA,5ALPHA,7ALPHA,8ALPHA,12ALPHA,14BETA,17ALPHA)-3,7,12-TRIHYDROXYCHOL-1-EN-24-AMIDE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 5-BETA-24-NOR-CHOLANE-3(ALPHA),7(ALPHA),12(ALPHA)-TRIOL, ...
著者Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M.
登録日2018-01-04
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
6P6Y
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BU of 6p6y by Molmil
Crystal structure of voltage-gated sodium channel NavAb V100C/Q150C disulfide crosslinked mutant in the activated state
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein
著者Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-din, T.M, Wang, L, Zheng, N, Catterall, W.A.
登録日2019-06-04
公開日2019-08-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.
Cell, 178, 2019
6MVV
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BU of 6mvv by Molmil
NavAb voltage-gated sodium channel, I217C/F203A
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, PHOSPHATE ION
著者Lenaeus, M.J, Catterall, W.A.
登録日2018-10-28
公開日2018-12-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Fenestrations control resting-state block of a voltage-gated sodium channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C1P
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BU of 6c1p by Molmil
HypoPP mutant
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHAPSO, Ion transport protein, ...
著者Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M.
登録日2018-01-05
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for gating pore current in periodic paralysis.
Nature, 557, 2018
3RW0
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BU of 3rw0 by Molmil
Crystal structure of the NavAb voltage-gated sodium channel (Met221Cys, 2.95 A)
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein
著者Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A.
登録日2011-05-06
公開日2011-07-13
最終更新日2011-07-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
6JUH
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BU of 6juh by Molmil
structure of CavAb in complex with efonidipine
分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-[phenyl-(phenylmethyl)amino]ethyl (4~{R})-5-(5,5-dimethyl-2-oxidanylidene-1,3,2$l^{5}-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate, ...
著者Tang, L, Xu, F.
登録日2019-04-13
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for efonidipine block of a voltage-gated Ca2+channel.
Biochem.Biophys.Res.Commun., 513, 2019

 

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