8P2G
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![BU of 8p2g by Molmil](/molmil-images/mine/8p2g) | Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane with a tRNA in pe/E chimeric state | 分子名称: | 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid, ... | 著者 | Gonzalez-Lopez, A, Selmer, M. | 登録日 | 2023-05-16 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.02 Å) | 主引用文献 | Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane. Sci Rep, 14, 2024
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6S0Z
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![BU of 6s0z by Molmil](/molmil-images/mine/6s0z) | Erythromycin Resistant Staphylococcus aureus 50S ribosome (delta R88 A89 uL22) in complex with erythromycin. | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A. | 登録日 | 2019-06-18 | 公開日 | 2019-08-21 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant. Sci Rep, 9, 2019
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6S0X
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![BU of 6s0x by Molmil](/molmil-images/mine/6s0x) | Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22) in complex with erythromycin. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A. | 登録日 | 2019-06-18 | 公開日 | 2019-08-21 | 実験手法 | ELECTRON MICROSCOPY (2.425 Å) | 主引用文献 | Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant. Sci Rep, 9, 2019
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8P2F
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![BU of 8p2f by Molmil](/molmil-images/mine/8p2f) | Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane in post-translocational state | 分子名称: | 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid, ... | 著者 | Gonzalez-Lopez, A, Selmer, M. | 登録日 | 2023-05-16 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.44 Å) | 主引用文献 | Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane. Sci Rep, 14, 2024
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7ASM
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![BU of 7asm by Molmil](/molmil-images/mine/7asm) | |
8P2H
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![BU of 8p2h by Molmil](/molmil-images/mine/8p2h) | |
6HMA
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![BU of 6hma by Molmil](/molmil-images/mine/6hma) | Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Eyal, Z, Cimicata, G, Matzov, D, Fox, T, de Val, N, Zimmerman, E, Bashan, A, Yonath, A. | 登録日 | 2018-09-12 | 公開日 | 2018-11-14 | 最終更新日 | 2020-05-27 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit To Be Published
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7ASN
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6WQN
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![BU of 6wqn by Molmil](/molmil-images/mine/6wqn) | |
7P48
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![BU of 7p48 by Molmil](/molmil-images/mine/7p48) | Staphylococcus aureus ribosome in complex with Sal(B) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Nicholson, D, Ranson, N.A, O'Neill, A.J. | 登録日 | 2021-07-09 | 公開日 | 2022-02-02 | 最終更新日 | 2022-03-09 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci. Nucleic Acids Res., 50, 2022
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7TTW
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![BU of 7ttw by Molmil](/molmil-images/mine/7ttw) | 50S ribosomal subunit from Staphylococcus aureus containing double mutation in uL3 imparting linezolid resistance | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Belousoff, M.J, Piper, S, Johnson, R. | 登録日 | 2022-02-02 | 公開日 | 2022-07-06 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid. Microbiol Spectr, 10, 2022
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7TTU
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![BU of 7ttu by Molmil](/molmil-images/mine/7ttu) | 50S ribosomal subunit from Staphylococcus aureus (Strain ATCC43300) | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Belousoff, M.J, Piper, S, Johnson, R. | 登録日 | 2022-02-01 | 公開日 | 2022-07-06 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid. Microbiol Spectr, 10, 2022
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6DDD
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![BU of 6ddd by Molmil](/molmil-images/mine/6ddd) | Structure of the 50S ribosomal subunit from Methicillin Resistant Staphylococcus aureus in complex with the oxazolidinone antibiotic LZD-5 | 分子名称: | 2,2-dichloro-N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide, 23S rRNA, 50S ribosomal protein L13, ... | 著者 | Belousoff, M.J, Venugopal, H, Bamert, R.S, Lithgow, T. | 登録日 | 2018-05-10 | 公開日 | 2019-03-20 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria. ChemMedChem, 14, 2019
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6DDG
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![BU of 6ddg by Molmil](/molmil-images/mine/6ddg) | Structure of the 50S ribosomal subunit from Methicillin Resistant Staphylococcus aureus in complex with the oxazolidinone antibiotic LZD-6 | 分子名称: | 2-chloro-N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide, 23S rRNA, 50S ribosomal protein L13, ... | 著者 | Belousoff, M.J, Venugopal, H, Bamert, R.S, Lithgow, T. | 登録日 | 2018-05-10 | 公開日 | 2019-03-20 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria. ChemMedChem, 14, 2019
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6WQQ
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6WRU
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![BU of 6wru by Molmil](/molmil-images/mine/6wru) | |
7NHM
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![BU of 7nhm by Molmil](/molmil-images/mine/7nhm) | 70S ribosome from Staphylococcus aureus | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Crowe-McAuliffe, C, Murina, V, Hauryliuk, V, Wilson, D.N. | 登録日 | 2021-02-10 | 公開日 | 2021-05-05 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens. Nat Commun, 12, 2021
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6YEF
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![BU of 6yef by Molmil](/molmil-images/mine/6yef) | 70S initiation complex with assigned rRNA modifications from Staphylococcus aureus | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ... | 著者 | Fatkhullin, B, Golubev, A, Khusainov, I, Yusupova, G, Yusupov, M. | 登録日 | 2020-03-24 | 公開日 | 2021-01-27 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 angstrom resolution. Febs Lett., 594, 2020
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6S12
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![BU of 6s12 by Molmil](/molmil-images/mine/6s12) | Erythromycin Resistant Staphylococcus aureus 50S ribosome (delta R88 A89 uL22). | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Halfon, Y, Matozv, D, Eyal, Z, Bashan, A, Zimmerman, E, Kjeldgaard, J, Ingmer, H, Yonath, A. | 登録日 | 2019-06-18 | 公開日 | 2019-08-21 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant. Sci Rep, 9, 2019
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6WRS
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6SJ6
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![BU of 6sj6 by Molmil](/molmil-images/mine/6sj6) | Cryo-EM structure of 50S-RsfS complex from Staphylococcus aureus | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Khusainov, I, Pellegrino, S, Yusupova, G, Yusupov, M, Fatkhullin, B. | 登録日 | 2019-08-12 | 公開日 | 2020-04-08 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Mechanism of ribosome shutdown by RsfS in Staphylococcus aureus revealed by integrative structural biology approach. Nat Commun, 11, 2020
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4WFA
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![BU of 4wfa by Molmil](/molmil-images/mine/4wfa) | The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with linezolid | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Eyal, Z, Matzov, D, Krupkin, M, Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.E. | 登録日 | 2014-09-14 | 公開日 | 2015-10-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.392 Å) | 主引用文献 | Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus. Proc.Natl.Acad.Sci.USA, 112, 2015
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4WF9
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![BU of 4wf9 by Molmil](/molmil-images/mine/4wf9) | The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with telithromycin | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Eyal, Z, Matzov, D, Krupkin, M, Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.E. | 登録日 | 2014-09-14 | 公開日 | 2015-10-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.427 Å) | 主引用文献 | Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus. Proc.Natl.Acad.Sci.USA, 112, 2015
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4WFB
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![BU of 4wfb by Molmil](/molmil-images/mine/4wfb) | The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with BC-3205 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S rRNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Eyal, Z, Matzov, D, Krupkin, M, Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.E. | 登録日 | 2014-09-14 | 公開日 | 2015-10-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.43 Å) | 主引用文献 | Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus. Proc.Natl.Acad.Sci.USA, 112, 2015
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5NRG
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![BU of 5nrg by Molmil](/molmil-images/mine/5nrg) | The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with RB02 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Yonath, A, Matzov, D, Eyal, Z, Ben Hamou, R, Zimmerman, E, Rozenberg, H, Bashan, A, Fridman, M. | 登録日 | 2017-04-23 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.442 Å) | 主引用文献 | Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus. Nucleic Acids Res., 45, 2017
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