7DFW
 
 | | Cryo_EM structure of delta N-NPC1L1-CLR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hu, M, Sun, S. | | 登録日 | 2020-11-10 | | 公開日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | | 主引用文献 | Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake.
Sci Adv, 7, 2021
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3QNT
 | | NPC1L1 (NTD) Structure | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Niemann-Pick C1-like protein 1 | | 著者 | Kwon, H.J. | | 登録日 | 2011-02-09 | | 公開日 | 2011-05-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | The Structure of the NPC1L1 N-Terminal Domain in a Closed Conformation.
Plos One, 6, 2011
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7DF8
 | | full length hNPC1L1-Apo | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hu, M, Sun, S, Sui, S. | | 登録日 | 2020-11-06 | | 公開日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake.
Sci Adv, 7, 2021
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7N4X
 | | Structure of human NPC1L1 mutant-W347R | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Li, X, Long, T. | | 登録日 | 2021-06-04 | | 公開日 | 2021-09-01 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | | 主引用文献 | Structures of dimeric human NPC1L1 provide insight into mechanisms for cholesterol absorption.
Sci Adv, 7, 2021
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7N4U
 | | Structure of human NPC1L1 | | 分子名称: | (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Li, X, Long, T. | | 登録日 | 2021-06-04 | | 公開日 | 2021-09-01 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | Structures of dimeric human NPC1L1 provide insight into mechanisms for cholesterol absorption.
Sci Adv, 7, 2021
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7DFZ
 | | Cryo_EM structure of delta N-NPC1L1-EZE | | 分子名称: | (3~{R},4~{S})-1-(4-fluorophenyl)-3-[(3~{S})-3-(4-fluorophenyl)-3-oxidanyl-propyl]-4-(4-hydroxyphenyl)azetidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hu, M, Sun, S. | | 登録日 | 2020-11-10 | | 公開日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake.
Sci Adv, 7, 2021
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7N4V
 | | Structure of cholesterol-bound human NPC1L1 | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Li, X, Long, T. | | 登録日 | 2021-06-04 | | 公開日 | 2021-09-01 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Structures of dimeric human NPC1L1 provide insight into mechanisms for cholesterol absorption.
Sci Adv, 7, 2021
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