7N4V
Structure of cholesterol-bound human NPC1L1
Summary for 7N4V
Entry DOI | 10.2210/pdb7n4v/pdb |
EMDB information | 24179 |
Descriptor | Isoform 2 of NPC1-like intracellular cholesterol transporter 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | transporter, membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 299964.21 |
Authors | |
Primary citation | Long, T.,Liu, Y.,Qin, Y.,DeBose-Boyd, R.A.,Li, X. Structures of dimeric human NPC1L1 provide insight into mechanisms for cholesterol absorption. Sci Adv, 7:-, 2021 Cited by PubMed: 34407950DOI: 10.1126/sciadv.abh3997 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.58 Å) |
Structure validation
Download full validation report