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7N4V

Structure of cholesterol-bound human NPC1L1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Isoform 2 of NPC1-like intracellular cholesterol transporter 1polymer1332145904.02UniProt (Q9UHC9)
Pfam (PF16414)
Pfam (PF22314)
Pfam (PF12349)
Pfam (PF02460)
Homo sapiens (Human)Niemann-Pick C1-like protein 1
2C, D, E, F, G...
(C, D, E, F, G...)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.46In PDB
GlyTouCan (G42666HT)
3I, J, K, L, R...
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.28Chemie (NAG)
4M, N, O, V, W...
(A, B)
CHOLESTEROLnon-polymer386.76Chemie (CLR)
5P, Q
(A, B)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.12Chemie (POV)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight291808.1
BranchedNumber of molecules6
Total formula weight2546.4
Non-Polymers*Number of molecules16
Total formula weight5609.7
All*Total formula weight299964.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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