7N4V
Structure of cholesterol-bound human NPC1L1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Isoform 2 of NPC1-like intracellular cholesterol transporter 1 | polymer | 1332 | 145904.0 | 2 | UniProt (Q9UHC9) Pfam (PF16414) Pfam (PF22314) Pfam (PF12349) Pfam (PF02460) In PDB | Homo sapiens (Human) | Niemann-Pick C1-like protein 1 |
2 | C, D, E, F, G... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
4 | A, B | CHOLESTEROL | non-polymer | 386.7 | 6 | Chemie (CLR) | |||
5 | A, B | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 2 | Chemie (POV) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 291808.1 | |
Branched | Number of molecules | 6 |
Total formula weight | 2546.4 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 5609.7 | |
All* | Total formula weight | 299964.2 |