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PDB: 15 件
6WQN
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Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, contezolid
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Belousoff, M.J.
登録日2020-04-29
公開日2020-06-03
最終更新日2020-12-16
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020
7TTW
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50S ribosomal subunit from Staphylococcus aureus containing double mutation in uL3 imparting linezolid resistance
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Belousoff, M.J, Piper, S, Johnson, R.
登録日2022-02-02
公開日2022-07-06
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid.
Microbiol Spectr, 10, 2022
7TTU
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50S ribosomal subunit from Staphylococcus aureus (Strain ATCC43300)
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Belousoff, M.J, Piper, S, Johnson, R.
登録日2022-02-01
公開日2022-07-06
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid.
Microbiol Spectr, 10, 2022
6WRU
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BU of 6wru by Molmil
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with an isomer of the tedizolid
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Belousoff, M.J.
登録日2020-04-30
公開日2020-06-03
最終更新日2020-12-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020
6WQQ
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BU of 6wqq by Molmil
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, radezolid
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Belousoff, M.J.
登録日2020-04-29
公開日2020-06-03
最終更新日2020-12-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020
7NHL
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VgaA-LC, an antibiotic resistance ABCF, in complex with 70S ribosome from Staphylococcus aureus
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Crowe-McAuliffe, C, Murina, V, Hauryliuk, V, Wilson, D.N.
登録日2021-02-10
公開日2021-05-05
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
7NHM
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70S ribosome from Staphylococcus aureus
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Crowe-McAuliffe, C, Murina, V, Hauryliuk, V, Wilson, D.N.
登録日2021-02-10
公開日2021-05-05
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
6DDD
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Structure of the 50S ribosomal subunit from Methicillin Resistant Staphylococcus aureus in complex with the oxazolidinone antibiotic LZD-5
分子名称: 2,2-dichloro-N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide, 23S rRNA, 50S ribosomal protein L13, ...
著者Belousoff, M.J, Venugopal, H, Bamert, R.S, Lithgow, T.
登録日2018-05-10
公開日2019-03-20
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria.
ChemMedChem, 14, 2019
6DDG
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Structure of the 50S ribosomal subunit from Methicillin Resistant Staphylococcus aureus in complex with the oxazolidinone antibiotic LZD-6
分子名称: 2-chloro-N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide, 23S rRNA, 50S ribosomal protein L13, ...
著者Belousoff, M.J, Venugopal, H, Bamert, R.S, Lithgow, T.
登録日2018-05-10
公開日2019-03-20
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献cryoEM-Guided Development of Antibiotics for Drug-Resistant Bacteria.
ChemMedChem, 14, 2019
6WRS
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BU of 6wrs by Molmil
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, tedizolid
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Belousoff, M.J.
登録日2020-04-30
公開日2020-06-03
最終更新日2020-12-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020
6YEF
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BU of 6yef by Molmil
70S initiation complex with assigned rRNA modifications from Staphylococcus aureus
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ...
著者Fatkhullin, B, Golubev, A, Khusainov, I, Yusupova, G, Yusupov, M.
登録日2020-03-24
公開日2021-01-27
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 angstrom resolution.
Febs Lett., 594, 2020
5T7V
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BU of 5t7v by Molmil
Methicillin Resistant, Linezolid resistant Staphylococcus aureus 70S ribosome (delta S145 uL3)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Belousoff, M.J, Lithgow, T, Eyal, Z, Yonath, A, Radjainia, M.
登録日2016-09-06
公開日2017-05-31
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Basis for Linezolid Binding Site Rearrangement in theStaphylococcus aureusRibosome.
MBio, 8, 2017
5ND8
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BU of 5nd8 by Molmil
Hibernating ribosome from Staphylococcus aureus (Unrotated state)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Khusainov, I, Vicens, Q, Ayupov, R, Usachev, K, Myasnikov, A, Simonetti, A, Validov, S, Kieffer, B, Yusupova, G, Yusupov, M, Hashem, Y.
登録日2017-03-07
公開日2017-06-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF.
EMBO J., 36, 2017
5ND9
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BU of 5nd9 by Molmil
Hibernating ribosome from Staphylococcus aureus (Rotated state)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Khusainov, I, Vicens, Q, Ayupov, R, Usachev, K, Myasnikov, A, Simonetti, A, Validov, S, Kieffer, B, Yusupova, G, Yusupov, M, Hashem, Y.
登録日2017-03-07
公開日2017-06-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF.
EMBO J., 36, 2017
5LI0
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BU of 5li0 by Molmil
70S ribosome from Staphylococcus aureus
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Khusainov, I, Vicens, Q, Bochler, A, Grosse, F, Myasnikov, A, Menetret, J.F, Chicher, J, Marzi, S, Romby, P, Yusupova, G, Yusupov, M, Hashem, Y.
登録日2016-07-13
公開日2016-12-28
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the 70S ribosome from human pathogen Staphylococcus aureus.
Nucleic Acids Res., 44, 2016

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件を2024-08-07に公開中

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