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PDB: 14 件

6AT6
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Crystal structure of the KFJ5 TCR
分子名称: T-cell receptor alpha variable 4, T-cell receptor, sp3.4 alpha chain chimera, ...
著者Gully, B.S, Rossjohn, J.
登録日2017-08-28
公開日2018-02-28
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.417 Å)
主引用文献Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.
Nat Commun, 9, 2018
7N4K
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6218 TCR in complex with H2-Db PA 224
分子名称: Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ...
著者Szeto, C, Gras, S.
登録日2021-06-04
公開日2022-07-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.
Nat Commun, 13, 2022
7N5C
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6218 TCR in complex with H2Db PA with an engineered TCR-pMHC disulfide bond
分子名称: Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 with T-cell receptor, sp3.4 alpha chain, ...
著者Szeto, C, Gras, S.
登録日2021-06-05
公開日2022-07-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.
Nat Commun, 13, 2022
7N5P
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6218 TCR in complex with H2-Db PA224-233 with a cysteine mutant
分子名称: Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ...
著者Szeto, C, Gras, S.
登録日2021-06-06
公開日2022-07-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.
Nat Commun, 13, 2022
7M72
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MHC-like protein complex structure
分子名称: (3R)-N-[(2S,3R)-1-(alpha-D-galactopyranosyloxy)-3-hydroxy-15-methylhexadecan-2-yl]-3-hydroxyheptadecanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Thirunavukkarasu, P, Le Nours, J, Rossjohn, J.
登録日2021-03-26
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Host immunomodulatory lipids created by symbionts from dietary amino acids.
Nature, 600, 2021
6Q3S
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Engineered Human HLA_A2 MHC Class I molecule in complex with TCR and SV9 peptide
分子名称: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
著者Meijers, R, Anjanappa, R, Springer, S, Garcia-Alai, M.
登録日2018-12-04
公開日2019-07-24
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献High-throughput peptide-MHC complex generation and kinetic screenings of TCRs with peptide-receptive HLA-A*02:01 molecules.
Sci Immunol, 4, 2019
4MNQ
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TCR-peptide specificity overrides affinity enhancing TCR-MHC interactions
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Sewell, A.K, Jakobsen, B.K.
登録日2013-09-11
公開日2013-11-13
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.742 Å)
主引用文献T-cell receptor (TCR)-peptide specificity overrides affinity-enhancing TCR-major histocompatibility complex interactions.
J.Biol.Chem., 289, 2014
6PY2
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HLA-TCR complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DQ2.2-glut-L1, GLYCEROL, ...
著者Ting, Y.T, Peteren, J, Reid, H.H, Rossjohn, J.
登録日2019-07-28
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.82543421 Å)
主引用文献A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease.
Proc.Natl.Acad.Sci.USA, 117, 2020
5WKF
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D30 TCR in complex with HLA-A*11:01-GTS1
分子名称: Beta-2-microglobulin, D30 TCR beta chain, GTS1 peptide, ...
著者Gras, S, Rossjohn, J.
登録日2017-07-25
公開日2017-09-20
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Nat. Immunol., 18, 2017
3PQY
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Crystal Structure of 6218 TCR in complex with the H2Db-PA224
分子名称: 10-mer peptide from RNA-directed RNA polymerase, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Gras, S, Guillonneau, C, Turner, S.J, Rossjohn, J.
登録日2010-11-28
公開日2011-05-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.192 Å)
主引用文献Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses
Proc.Natl.Acad.Sci.USA, 108, 2011
5NHT
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human 199.54-16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2
分子名称: Beta-2-microglobulin, CHLORIDE ION, HLA class I histocompatibility antigen, ...
著者Exertier, C, Reiser, J.-B, Lantez, V, Chouquet, A, Bonneville, M, Saulquin, X, Housset, D.
登録日2017-03-22
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献human 199.54-16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2
To Be Published
5WKH
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D30 TCR in complex with HLA-A*11:01-GTS3
分子名称: Beta-2-microglobulin, D30 TCR beta chain, GTS3 peptide, ...
著者Gras, S, Rossjohn, J.
登録日2017-07-25
公開日2017-09-20
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Nat. Immunol., 18, 2017
4GG6
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Protein complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DQ alpha 1 chain, ...
著者Broughton, S.E, Theodossis, A, Petersen, J, Reid, H.H, Rossjohn, J.
登録日2012-08-06
公開日2012-10-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease.
Immunity, 37, 2012
4GG8
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Immune Receptor
分子名称: T-CELL RECEPTOR, SP3.4 ALPHA CHAIN, SP3.4 BETA CHAIN, ...
著者Broughton, S.E, Theodossis, A, Petersen, J, Reid, H.H, Rossjohn, J.
登録日2012-08-06
公開日2012-10-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease.
Immunity, 37, 2012

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件を2024-07-03に公開中

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