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PDB: 4 件

8DC6
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BU of 8dc6 by Molmil
Crystal structure of p53 Y220C covalently bound to indole KG6
分子名称: 1-(2-methylprop-2-enoyl)-1H-indole-3-carbaldehyde, bound form, Cellular tumor antigen p53, ...
著者Guiley, K.Z, Shokat, K.M.
登録日2022-06-15
公開日2022-10-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.60000908 Å)
主引用文献A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability.
Cancer Discov, 13, 2023
8DC4
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BU of 8dc4 by Molmil
Crystal structure of p53 Y220C covalently bound to carbazole KG3
分子名称: 9-propanoyl-9H-carbazole-3-carbaldehyde, bound form, Cellular tumor antigen p53, ...
著者Guiley, K.Z, Shokat, K.M.
登録日2022-06-15
公開日2022-10-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability.
Cancer Discov, 13, 2023
8DC7
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BU of 8dc7 by Molmil
Crystal structure of p53 Y220C covalently bound to indole KG10
分子名称: 4-[4-(4-methylpiperazin-1-yl)phenyl]-1-(2-methylprop-2-enoyl)-1H-indole-3-carbaldehyde, bound form, Cellular tumor antigen p53, ...
著者Guiley, K.Z, Shokat, K.M.
登録日2022-06-15
公開日2022-10-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9870069 Å)
主引用文献A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability.
Cancer Discov, 13, 2023
8DC8
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BU of 8dc8 by Molmil
Crystal structure of p53 Y220C covalently bound to azaindole KG13
分子名称: 2-methyl-1-[(4P)-3-methyl-4-(2-methyl-1,2,3,4-tetrahydroisoquinolin-6-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl]prop-2-en-1-one, bound form, Cellular tumor antigen p53, ...
著者Guiley, K.Z, Shokat, K.M.
登録日2022-06-15
公開日2022-10-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7200973 Å)
主引用文献A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability.
Cancer Discov, 13, 2023

224572

件を2024-09-04に公開中

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