6LVX
 
 | | Crystal structure of TLR7/Cpd-1 (SM-374527) complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-azanyl-2-butoxy-9-(phenylmethyl)-7H-purin-8-one, ... | | 著者 | Zhang, Z, Ohto, U, Shimizu, T. | | 登録日 | 2020-02-06 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Structural analysis reveals TLR7 dynamics underlying antagonism.
Nat Commun, 11, 2020
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6LVY
 | | Crystal structure of TLR7/Cpd-2 (SM-360320) complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-azanyl-2-(2-methoxyethoxy)-9-(phenylmethyl)-7H-purin-8-one, ... | | 著者 | Zhang, Z, Ohto, U, Shimizu, T. | | 登録日 | 2020-02-06 | | 公開日 | 2020-11-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural analysis reveals TLR7 dynamics underlying antagonism.
Nat Commun, 11, 2020
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6LW0
 | | Crystal structure of TLR7/Cpd-6 (DSR-139293) complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-ethoxy-8-(5-fluoranylpyridin-3-yl)-9-[[4-[[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]methyl]purin-6-amine, ... | | 著者 | Zhang, Z, Ohto, U, Shimizu, T. | | 登録日 | 2020-02-06 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural analysis reveals TLR7 dynamics underlying antagonism.
Nat Commun, 11, 2020
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6LW1
 | | Cryo-EM structure of TLR7/Cpd-7 (DSR-139970) complex in open form | | 分子名称: | 2-ethoxy-8-(5-fluoranylpyridin-3-yl)-6-methyl-9-[[4-[[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]methyl]purine, Toll-like receptor 7 | | 著者 | Zhang, Z, Ohto, U, Shimizu, T. | | 登録日 | 2020-02-06 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural analysis reveals TLR7 dynamics underlying antagonism.
Nat Commun, 11, 2020
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6LVZ
 | | Crystal structure of TLR7/Cpd-3 (SM-394830) complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-azanyl-2-(2-methoxyethoxy)-9-(pyridin-3-ylmethyl)-7H-purin-8-one, ... | | 著者 | Zhang, Z, Ohto, U, Shimizu, T. | | 登録日 | 2020-02-06 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | Structural analysis reveals TLR7 dynamics underlying antagonism.
Nat Commun, 11, 2020
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