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PDB: 8 件

6O5U
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BU of 6o5u by Molmil
AAC-VIa bound to Kanamycin A
分子名称: Aminoglycoside N(3)-acetyltransferase, KANAMYCIN A, MAGNESIUM ION
著者Kumar, P, Cuneo, M.J.
登録日2019-03-04
公開日2019-09-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad.
Angew.Chem.Int.Ed.Engl., 58, 2019
6NTI
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BU of 6nti by Molmil
Neutron/X-ray crystal structure of AAC-VIa bound to kanamycin b
分子名称: (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, Aminoglycoside N(3)-acetyltransferase, MAGNESIUM ION
著者Cuneo, M.J, Kumar, P.
登録日2019-01-29
公開日2019-09-25
最終更新日2024-04-03
実験手法NEUTRON DIFFRACTION (2.3 Å), X-RAY DIFFRACTION
主引用文献Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad.
Angew.Chem.Int.Ed.Engl., 58, 2019
6NP4
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BU of 6np4 by Molmil
AAC-VIa bound to Tobramycin
分子名称: Aminoglycoside N(3)-acetyltransferase, MAGNESIUM ION, TOBRAMYCIN
著者Kumar, P, Cuneo, M.J.
登録日2019-01-17
公開日2019-09-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.151 Å)
主引用文献Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad.
Angew.Chem.Int.Ed.Engl., 58, 2019
6NP1
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BU of 6np1 by Molmil
Product state mimicry leads to aminoglycoside discrimination in an antibiotic acetyltransferase
分子名称: Aminoglycoside N(3)-acetyltransferase, MAGNESIUM ION
著者Kumar, P, Cuneo, M.J.
登録日2019-01-17
公開日2019-09-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad.
Angew.Chem.Int.Ed.Engl., 58, 2019
6NP3
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BU of 6np3 by Molmil
AAC-VIa bound to Gentamicin
分子名称: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, Aminoglycoside N(3)-acetyltransferase, MAGNESIUM ION
著者Kumar, P, Cuneo, M.J.
登録日2019-01-17
公開日2019-09-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad.
Angew.Chem.Int.Ed.Engl., 58, 2019
6NP2
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BU of 6np2 by Molmil
AAC-VIa bound to Sisomicin
分子名称: (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, Aminoglycoside N(3)-acetyltransferase, MAGNESIUM ION
著者Kumar, P, Cuneo, M.J.
登録日2019-01-17
公開日2019-09-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad.
Angew.Chem.Int.Ed.Engl., 58, 2019
6NTJ
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BU of 6ntj by Molmil
Neutron/X-ray crystal structure of AAC-VIa bound to gentamicin C1A
分子名称: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, Aminoglycoside N(3)-acetyltransferase, MAGNESIUM ION
著者Cuneo, M.J, Kumar, P.
登録日2019-01-29
公開日2019-09-25
最終更新日2024-04-03
実験手法NEUTRON DIFFRACTION (1.9 Å), X-RAY DIFFRACTION
主引用文献Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad.
Angew.Chem.Int.Ed.Engl., 58, 2019
6NP5
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BU of 6np5 by Molmil
AAC-VIa bound to Kanamycin B
分子名称: (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, Aminoglycoside N(3)-acetyltransferase, MAGNESIUM ION
著者Kumar, P, Cuneo, M.J.
登録日2019-01-17
公開日2019-09-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.353 Å)
主引用文献Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad.
Angew.Chem.Int.Ed.Engl., 58, 2019

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件を2024-10-30に公開中

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