6O5U

AAC-VIa bound to Kanamycin A

Summary for 6O5U

Entry DOI	10.2210/pdb6o5u/pdb
Descriptor	Aminoglycoside N(3)-acetyltransferase, KANAMYCIN A, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	antibiotic modifying enzyme, substrate selectivity, antibiotic, transferase, transferase-antibiotic complex, transferase/antibiotic
Biological source	Enterobacteriaceae
Total number of polymer chains	1
Total formula weight	32839.24
Authors	Kumar, P.,Cuneo, M.J. (deposition date: 2019-03-04, release date: 2019-09-25, Last modification date: 2023-10-11)
Primary citation	Kumar, P.,Agarwal, P.K.,Waddell, M.B.,Mittag, T.,Serpersu, E.H.,Cuneo, M.J. Low-Barrier and Canonical Hydrogen Bonds Modulate Activity and Specificity of a Catalytic Triad. Angew.Chem.Int.Ed.Engl., 58:16260-16266, 2019 Cited by PubMed: 31515870 DOI: 10.1002/anie.201908535 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation