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PDB: 223166 件
1KKQ
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Crystal structure of the human PPAR-alpha ligand-binding domain in complex with an antagonist GW6471 and a SMRT corepressor motif
分子名称: N-((2S)-2-({(1Z)-1-METHYL-3-OXO-3-[4-(TRIFLUOROMETHYL) PHENYL]PROP-1-ENYL}AMINO)-3-{4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL}PROPYL)PROPANAMIDE, NUCLEAR RECEPTOR CO-REPRESSOR 2, PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR
著者Xu, H.E, Stanley, T.B, Montana, V.G, Lambert, M.H, Shearer, B.G, Cobb, J.E, McKee, D.D, Galardi, C.M, Nolte, R.T, Parks, D.J.
登録日2001-12-10
公開日2002-02-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha.
Nature, 415, 2002
1KKR
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CRYSTAL STRUCTURE OF CITROBACTER AMALONATICUS METHYLASPARTATE AMMONIA LYASE CONTAINING (2S,3S)-3-METHYLASPARTIC ACID
分子名称: (2S,3S)-3-methyl-aspartic acid, 3-METHYLASPARTATE AMMONIA-LYASE, MAGNESIUM ION
著者Levy, C.W, Buckley, P.A, Sedelnikova, S, Kato, K, Asano, Y, Rice, D.W, Baker, P.J.
登録日2001-12-10
公開日2002-01-30
最終更新日2014-11-19
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insights into enzyme evolution revealed by the structure of methylaspartate ammonia lyase.
Structure, 10, 2002
1KKS
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Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression
分子名称: 5'-R(*GP*GP*AP*AP*GP*GP*CP*CP*CP*UP*UP*UP*UP*CP*AP*GP*GP*GP*CP*CP*AP*CP*CP*C)-3'
著者Zanier, K, Luyten, I, Crombie, C, Muller, B, Schuemperli, D, Linge, J.P, Nilges, M, Sattler, M.
登録日2001-12-10
公開日2002-03-13
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression.
RNA, 8, 2002
1KKT
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Structure of P. citrinum alpha 1,2-mannosidase reveals the basis for differences in specificity of the ER and Golgi Class I enzymes
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mannosyl-oligosaccharide alpha-1,2-mannosidase, ...
著者Lobsanov, Y.D, Vallee, F, Imberty, A, Yoshida, T, Yip, P, Herscovics, A, Howell, P.L.
登録日2001-12-10
公開日2002-01-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Penicillium citrinum alpha 1,2-mannosidase reveals the basis for differences in specificity of the endoplasmic reticulum and Golgi class I enzymes.
J.Biol.Chem., 277, 2002
1KKU
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Crystal structure of nuclear human nicotinamide mononucleotide adenylyltransferase
分子名称: NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE
著者Garavaglia, S, D'Angelo, I, Emanuelli, M, Carnevali, F, Pierella, F, Magni, G, Rizzi, M.
登録日2001-12-10
公開日2002-06-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasis.
J.Biol.Chem., 277, 2002
1KKV
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NMR Solution Structure of d(CCACGCGTGG)2, parent to G-T mismatch structure
分子名称: 5'-D(*CP*CP*AP*CP*GP*CP*GP*TP*GP*G)-3'
著者Isaacs, R.J, Spielmann, H.P.
登録日2001-12-10
公開日2002-06-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural differences in the NOE-derived structure of G-T mismatched DNA relative to normal DNA are correlated with differences in (13)C relaxation-based internal dynamics.
J.Mol.Biol., 319, 2002
1KKW
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NMR Solution Structure of d(CCATGCGTGG)2, G-T mismatch structure
分子名称: 5'-D(*CP*CP*AP*TP*GP*CP*GP*TP*GP*G)-3'
著者Isaacs, R.J, Spielmann, H.P.
登録日2001-12-10
公開日2002-06-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural differences in the NOE-derived structure of G-T mismatched DNA relative to normal DNA are correlated with differences in (13)C relaxation-based internal dynamics.
J.Mol.Biol., 319, 2002
1KKX
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Solution structure of the DNA-binding domain of ADR6
分子名称: Transcription regulatory protein ADR6
著者Tu, X, Wu, J, Xu, Y, Shi, Y.
登録日2001-12-10
公開日2002-07-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献1H, 13C and 15N resonance assignments and secondary structure of ADR6 DNA-binding domain.
J.Biomol.Nmr, 21, 2001
1KL1
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Crystal Structure of Serine Hydroxymethyltransferase Complexed with Glycine
分子名称: GLYCINE, PYRIDOXAL-5'-PHOSPHATE, Serine Hydroxymethyltransferase
著者Trivedi, V, Gupta, A, Jala, V.R, Saravanan, P, Rao, G.S.J, Rao, N.A, Savithri, H.S, Subramanya, H.S.
登録日2001-12-11
公開日2002-07-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus stearothermophilus: insights into the catalytic mechanism.
J.Biol.Chem., 277, 2002
1KL2
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Crystal Structure of Serine Hydroxymethyltransferase Complexed with Glycine and 5-formyl tetrahydrofolate
分子名称: GLYCINE, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, PYRIDOXAL-5'-PHOSPHATE, ...
著者Trivedi, V, Gupta, A, Jala, V.R, Saravanan, P, Rao, G.S.J, Rao, N.A, Savithri, H.S, Subramanya, H.S.
登録日2001-12-11
公開日2002-07-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus stearothermophilus: insights into the catalytic mechanism.
J.Biol.Chem., 277, 2002
1KL3
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an engineered streptavidin with improved affinity for the strep-tag II peptide : SAm1-StrepII
分子名称: strep-tag II peptide, streptavidin
著者Korndoerfer, I.P, Skerra, A.
登録日2001-12-11
公開日2002-04-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site.
Protein Sci., 11, 2002
1KL4
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AN ENGINEERED STREPTAVIDIN WITH IMPROVED AFFINITY FOR THE STREP-TAG II PEPTIDE : apo-SAM2
分子名称: streptavidin
著者Korndoerfer, I.P, Skerra, A.
登録日2001-12-11
公開日2002-04-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site.
Protein Sci., 11, 2002
1KL5
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an engineered streptavidin with improved affinity for the strep-tag II peptide : SAm2-StrepII
分子名称: strep-tag II, streptavidin
著者Korndoerfer, I.P, Skerra, A.
登録日2001-12-11
公開日2002-04-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site.
Protein Sci., 11, 2002
1KL6
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Thermolysin complexed with Z-L-Alanine (benzyloxycarbonyl-L-Alanine)
分子名称: ALANINE, CALCIUM ION, Thermolysin, ...
著者Senda, M, Senda, T, Kidokoro, S.
登録日2001-12-11
公開日2002-12-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure analyses of Thermolysin in complex with its inhibitors.
To be Published
1KL7
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Crystal Structure of Threonine Synthase from Yeast
分子名称: PYRIDOXAL-5'-PHOSPHATE, Threonine Synthase
著者Garrido-Franco, M, Ehlert, S, Messerschmidt, A, Marinkovic, S, Huber, R, Laber, B, Bourenkov, G.P, Clausen, T.
登録日2001-12-11
公開日2002-04-24
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and function of threonine synthase from yeast.
J.Biol.Chem., 277, 2002
1KL8
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NMR STRUCTURAL ANALYSIS OF THE COMPLEX FORMED BETWEEN ALPHA-BUNGAROTOXIN AND THE PRINCIPAL ALPHA-NEUROTOXIN BINDING SEQUENCE ON THE ALPHA7 SUBUNIT OF A NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR
分子名称: ALPHA-BUNGAROTOXIN, NEURONAL ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA-7 CHAIN
著者Moise, L, Piserchio, A, Basus, V.J, Hawrot, E.
登録日2001-12-11
公開日2002-03-13
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.
J.Biol.Chem., 277, 2002
1KL9
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Crystal structure of the N-terminal segment of Human eukaryotic initiation factor 2alpha
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1, ZINC ION
著者Nonato, M.C, Widom, J, Clardy, J.
登録日2001-12-11
公開日2002-03-11
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the N-terminal segment of human eukaryotic translation initiation factor 2alpha
J.Biol.Chem., 277, 2002
1KLA
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SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 1-17 OF 33 STRUCTURES
分子名称: TRANSFORMING GROWTH FACTOR-BETA 1
著者Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A.
登録日1996-01-16
公開日1996-08-17
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
1KLC
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SOLUTION STRUCTURE OF TGF-B1, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: TRANSFORMING GROWTH FACTOR-BETA 1
著者Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A.
登録日1996-01-16
公開日1996-08-17
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
1KLD
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SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 18-33 OF 33 STRUCTURES
分子名称: TRANSFORMING GROWTH FACTOR-BETA 1
著者Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A.
登録日1996-01-16
公開日1996-08-17
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
1KLF
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FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE
分子名称: CHAPERONE PROTEIN FIMC, FIMH PROTEIN, alpha-D-mannopyranose
著者Hung, C.S, Bouckaert, J.
登録日2001-12-11
公開日2002-06-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection.
Mol.Microbiol., 44, 2002
1KLG
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Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
分子名称: ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ...
著者Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A.
登録日2001-12-11
公開日2002-08-02
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
1KLI
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Cofactor-and substrate-assisted activation of factor VIIa
分子名称: BENZAMIDINE, CALCIUM ION, GLYCEROL, ...
著者Sichler, K, Banner, D.W, D'Arcy, A, Hopfner, K.P, Huber, R, Bode, W, Kresse, G.B, Kopetzki, E, Brandstetter, H.
登録日2001-12-12
公開日2002-09-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Crystal Structure of Uninhibited Factor VIIa Link its Cofactor and Substrate-assisted Activation to Specific Interactions
J.Mol.Biol., 322, 2002
1KLJ
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Crystal structure of uninhibited factor VIIa
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, factor VIIa
著者Sichler, K, Banner, D, D'Arcy, A, Hopfner, K.P, Huber, R, Bode, W, Kresse, G.B, Kopetzki, E, Brandstetter, H.
登録日2001-12-12
公開日2002-10-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions.
J.Mol.Biol., 322, 2002
1KLK
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CRYSTAL STRUCTURE OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE TERNARY COMPLEX WITH PT653 AND NADPH
分子名称: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE
著者Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Rosowsky, A, Queener, S.F.
登録日2001-12-12
公開日2002-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH.
Acta Crystallogr.,Sect.D, 58, 2002

223166

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