PDB: 5689 resultsInfo pagesStatus searchChemie searchBIRD

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8EK4	De novo designed ice-binding proteins from twist-constrained helices Descriptor: Ice-binding protein TIP-99a Authors: Bera, A.K, De Haas, R.J. Deposit date: 2022-09-19 Release date: 2023-07-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.35 Å) Cite: De novo designed ice-binding proteins from twist-constrained helices. Proc.Natl.Acad.Sci.USA, 120, 2023
5WLJ	De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4EH1 Descriptor: De Novo Metal Binding Helical Bundle, ZINC ION Authors: Zhang, S.-Q, Liu, L, DeGrado, W.F. Deposit date: 2017-07-27 Release date: 2018-01-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.6 Å) Cite: De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles. J. Am. Chem. Soc., 140, 2018
8HDU	De novo design cavitated protein without predefined topology Descriptor: De novo design cavitated protein Authors: Hu, X, Xu, Y. Deposit date: 2022-11-06 Release date: 2023-01-18 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (2.71 Å) Cite: De novo design of cavity-containing proteins with a backbone-centered neural network energy function. Structure, 32, 2024
8HDV	De novo design cavitated protein without predefined topology Descriptor: De novo design cavitated protein Authors: Hu, X, Xu, Y. Deposit date: 2022-11-06 Release date: 2023-01-18 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (2.65 Å) Cite: De novo design of cavity-containing proteins with a backbone-centered neural network energy function. Structure, 32, 2024
8Y9C	De novo design mini-binder in complex with TcdB4 Descriptor: De novo design Minibinder, Toxin B, ZINC ION Authors: Lv, X.C, Lu, P.L. Deposit date: 2024-02-06 Release date: 2024-08-28 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (3 Å) Cite: De novo design of mini-protein binders broadly neutralizing Clostridioides difficile toxin B variants. Nat Commun, 15, 2024
6MSP	De novo Designed Protein Foldit3 Descriptor: De novo Designed Protein Foldit3 Authors: Liu, G, Ishida, Y, Swapna, G.V.T, Kleinfelter, S, Koepnick, B, Baker, D, Montelione, G.T. Deposit date: 2018-10-17 Release date: 2019-06-12 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: De novo protein design by citizen scientists. Nature, 570, 2019
6WI5	De novo designed protein Foldit4 Descriptor: De novo designed protein Foldit4 Authors: Bera, A.K, Koepnick, B, Boykov, A, Baker, D. Deposit date: 2020-04-08 Release date: 2020-04-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.83 Å) Cite: De novo design of protein logic gates. Science, 368, 2020
7SKP	De novo synthetic protein DIG14 (tetragonal space group) Descriptor: De novo synthetic protein DIG14 Authors: Mendes, S.R, Eckhard, U, Marcos, E, Gomis-Ruth, F.X. Deposit date: 2021-10-21 Release date: 2022-10-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: De novo design of immunoglobulin-like domains Nat Commun, 13, 2022
7SKN	De novo synthetic protein DIG8-CC (tetragonal space group) Descriptor: De novo synthetic protein DIG8-CC Authors: Mendes, S.R, Eckhard, U, Marcos, E, Gomis-Ruth, F.X. Deposit date: 2021-10-21 Release date: 2022-10-12 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: De novo design of immunoglobulin-like domains Nat Commun, 13, 2022
7SKO	De novo synthetic protein DIG8-CC (orthogonal space group) Descriptor: De novo synthetic protein DIG8-CC, MAGNESIUM ION Authors: Mendes, S.R, Eckhard, U, Marcos, E, Gomis-Ruth, F.X. Deposit date: 2021-10-21 Release date: 2022-10-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.05 Å) Cite: De novo design of immunoglobulin-like domains Nat Commun, 13, 2022
8UPB	De novo designed IL-6 mimetic Descriptor: De novo designed IL-6 mimetic Authors: Borowska, M.T, Jude, K.M, Garcia, K.C. Deposit date: 2023-10-22 Release date: 2024-08-28 Method: X-RAY DIFFRACTION (1.48 Å) Cite: De novo design of miniprotein antagonists of cytokine storm inducers. Nat Commun, 15, 2024
8JPA	De novo design cavitated protein without predefined topology Descriptor: De novo design cavitated protein Authors: Hu, X, Xu, Y. Deposit date: 2023-06-11 Release date: 2023-06-28 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: De novo design of cavity-containing proteins with a backbone-centered neural network energy function. Structure, 32, 2024
8TN1	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - apo Descriptor: De novo designed 4 helix bundles, SULFATE ION Authors: Lu, L, DeGrado, W.F. Deposit date: 2023-08-01 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (1.61 Å) Cite: De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
8TN6	De novo designed protein binds poly ADP ribose polymerase inhibitors (PARPi) - holo rucaparib Descriptor: De novo designed protein, Rucaparib Authors: Lu, L, DeGrado, W.F. Deposit date: 2023-08-01 Release date: 2024-04-24 Method: X-RAY DIFFRACTION (1.36 Å) Cite: De novo design of drug-binding proteins with predictable binding energy and specificity. Science, 384, 2024
8GJI	De novo design of high-affinity protein binders to bioactive helical peptides Descriptor: GCG binder, Glucagon Authors: Torres, S.V, Leung, P.J.Y, Bera, A.K, Baker, D, Kang, A. Deposit date: 2023-03-15 Release date: 2024-01-10 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.81 Å) Cite: De novo design of high-affinity binders of bioactive helical peptides. Nature, 626, 2024
8GJG	De novo design of high-affinity protein binders to bioactive helical peptides Descriptor: gluc_A04_0005, gluc_A04_0005 Binder Authors: Leung, P.J.Y, Bera, A.K, Torres, S.V, Baker, D, Kang, A. Deposit date: 2023-03-15 Release date: 2024-01-10 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.95 Å) Cite: De novo design of high-affinity binders of bioactive helical peptides. Nature, 626, 2024
7CBC	Crystal structure of a de novo designed switch protein caging a hemagglutinin binder Descriptor: De novo designed switch protein caging a hemagglutinin binder (sCageHA267_1S), ETHANOL Authors: Lee, H, Oh, B.-H, Baker, D. Deposit date: 2020-06-11 Release date: 2020-12-23 Last modified: 2021-03-31 Method: X-RAY DIFFRACTION (1.99 Å) Cite: De novo design of modular and tunable protein biosensors. Nature, 591, 2021
8UP1	CryoEM Structure of Allosterically Switchable De Novo Protein sr322, In Closed State without Effector Peptide Descriptor: De Novo Protein sr322 Authors: Weidle, C, Borst, A. Deposit date: 2023-10-20 Release date: 2024-08-14 Last modified: 2024-09-11 Method: ELECTRON MICROSCOPY (4.55 Å) Cite: De novo design of allosterically switchable protein assemblies. Nature, 632, 2024
8UTM	CryoEM Structure of Allosterically Switchable De Novo Protein sr322, In Closed State without Effector Peptide, off Target Multimeric State Descriptor: de novo protein sr322 Authors: Weidle, C, Borst, A. Deposit date: 2023-10-31 Release date: 2024-08-14 Last modified: 2024-09-18 Method: ELECTRON MICROSCOPY (4.32 Å) Cite: De novo design of allosterically switchable protein assemblies. Nature, 632, 2024
7M5T	Solution NMR structure of de novo designed protein 0515 Descriptor: De novo designed protein 0515 Authors: Ramelot, T.A, Hao, J, Baker, D, Montelione, G.T. Deposit date: 2021-03-24 Release date: 2021-12-15 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: De novo protein design by deep network hallucination. Nature, 600, 2021
6E5C	Solution NMR structure of a de novo designed double-stranded beta-helix Descriptor: De novo beta protein Authors: Marcos, E, Chidyausiku, T.M, McShan, A, Evangelidis, T, Nerli, S, Sgourakis, N, Tripsianes, K, Baker, D. Deposit date: 2018-07-19 Release date: 2018-11-07 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: De novo design of a non-local beta-sheet protein with high stability and accuracy. Nat. Struct. Mol. Biol., 25, 2018
7UWY	NMR solution structure of the De novo designed small beta-barrel protein 29_bp_sh3 Descriptor: De novo designed small beta-barrel protein 29_bp_sh3 Authors: Peterson, F.C, Kim, D.E, Jensen, D.R, Saleem, A, Chow, C.M, Volkman, B.F, Baker, D. Deposit date: 2022-05-04 Release date: 2023-03-22 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: De novo design of small beta barrel proteins. Proc.Natl.Acad.Sci.USA, 120, 2023
7UWZ	NMR solution structure of the De novo designed small beta-barrel protein 33_bp_sh3 Descriptor: De novo designed small beta-barrel protein 33_bp_sh3 Authors: Peterson, F.C, Kim, D.E, Jensen, D.R, Saleem, A, Chow, C.M, Volkman, B.F, Baker, D. Deposit date: 2022-05-04 Release date: 2023-03-22 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: De novo design of small beta barrel proteins. Proc.Natl.Acad.Sci.USA, 120, 2023
1PBZ	DE NOVO DESIGNED PEPTIDE-METALLOPORPHYRIN COMPLEX, SOLUTION STRUCTURE Descriptor: COPROPORPHYRIN I CONTAINING CO(III), De novo designed cyclic peptide Authors: Wang, J, Rosenblatt, M.M, Suslick, K.S. Deposit date: 2003-05-15 Release date: 2003-12-09 Last modified: 2024-11-06 Method: SOLUTION NMR Cite: De novo designed cyclic-peptide heme complexes Proc.Natl.Acad.Sci.USA, 100, 2003
6X1K	Solution NMR structure of de novo designed TMB2.3 Descriptor: De novo designed transmembrane beta-barrel TMB2.3 Authors: Liang, B, Vorobieva, A.A, Chow, C.M, Baker, D, Tamm, L.K. Deposit date: 2020-05-19 Release date: 2021-02-17 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: De novo design of transmembrane beta barrels. Science, 371, 2021

 

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