1RO4
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1PFT
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![BU of 1pft by Molmil](/molmil-images/mine/1pft) | N-TERMINAL DOMAIN OF TFIIB, NMR | Descriptor: | TFIIB, ZINC ION | Authors: | Zhu, W, Zeng, Q, Colangelo, C.M, Lewis, L.M, Summers, M.F, Scott, R.A. | Deposit date: | 1996-03-27 | Release date: | 1996-08-17 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The N-terminal domain of TFIIB from Pyrococcus furiosus forms a zinc ribbon. Nat.Struct.Biol., 3, 1996
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1DL6
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![BU of 1dl6 by Molmil](/molmil-images/mine/1dl6) | SOLUTION STRUCTURE OF HUMAN TFIIB N-TERMINAL DOMAIN | Descriptor: | TRANSCRIPTION FACTOR II B (TFIIB), ZINC ION | Authors: | Chen, H.-T, Legault, P, Glushka, J, Omichinski, J.G, Scott, R.A. | Deposit date: | 1999-12-08 | Release date: | 2000-10-18 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of a (Cys3His) zinc ribbon, a ubiquitous motif in archaeal and eucaryal transcription. Protein Sci., 9, 2000
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1RLY
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1VD4
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![BU of 1vd4 by Molmil](/molmil-images/mine/1vd4) | Solution structure of the zinc finger domain of TFIIE alpha | Descriptor: | Transcription initiation factor IIE, alpha subunit, ZINC ION | Authors: | Okuda, M, Tanaka, A, Arai, Y, Satoh, M, Okamura, H, Nagadoi, A, Hanaoka, F, Ohkuma, Y, Nishimura, Y. | Deposit date: | 2004-03-18 | Release date: | 2004-10-05 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | A novel zinc finger structure in the large subunit of human general transcription factor TFIIE. J.Biol.Chem., 279, 2004
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3WWL
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![BU of 3wwl by Molmil](/molmil-images/mine/3wwl) | Crystal structure of lysine biosynthetic amino acid carrier protein LysW from Thermus thermophilus conjugated with alpha-aminoadipate | Descriptor: | Alpha-aminoadipate carrier protein LysW, ZINC ION | Authors: | Yoshida, A, Tomita, T, Kuzuyama, T, Nishiyama, M. | Deposit date: | 2014-06-21 | Release date: | 2014-11-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural insight into amino group-carrier protein-mediated lysine biosynthesis: crystal structure of the LysZ·LysW complex from Thermus thermophilus. J.Biol.Chem., 290, 2015
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8BVW
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![BU of 8bvw by Molmil](/molmil-images/mine/8bvw) | RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. | Deposit date: | 2022-12-20 | Release date: | 2023-05-03 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
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7Q5B
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![BU of 7q5b by Molmil](/molmil-images/mine/7q5b) | Cryo-EM structure of Ty3 retrotransposon targeting a TFIIIB-bound tRNA gene | Descriptor: | DNA (19-MER), DNA (31-MER), DNA (34-MER), ... | Authors: | Abascal-Palacios, G, Jochem, L, Pla-Prats, C, Beuron, F, Vannini, A. | Deposit date: | 2021-11-03 | Release date: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (3.98 Å) | Cite: | Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes. Nat Commun, 12, 2021
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6O9L
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![BU of 6o9l by Molmil](/molmil-images/mine/6o9l) | Human holo-PIC in the closed state | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I. | Deposit date: | 2019-03-14 | Release date: | 2019-05-29 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Transcription preinitiation complex structure and dynamics provide insight into genetic diseases. Nat.Struct.Mol.Biol., 26, 2019
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8FFZ
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![BU of 8ffz by Molmil](/molmil-images/mine/8ffz) | TFIIIA-TFIIIC-Brf1-TBP complex bound to 5S rRNA gene | Descriptor: | DNA (151-MER), Transcription factor IIIA, Transcription factor IIIB 70 kDa subunit,TATA-box-binding protein, ... | Authors: | Talyzina, A, He, Y. | Deposit date: | 2022-12-11 | Release date: | 2023-06-21 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of TFIIIC-dependent RNA polymerase III transcription initiation. Mol.Cell, 83, 2023
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7LBM
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![BU of 7lbm by Molmil](/molmil-images/mine/7lbm) | Structure of the human Mediator-bound transcription pre-initiation complex | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Abdella, R, Talyzina, A, He, Y. | Deposit date: | 2021-01-08 | Release date: | 2021-03-24 | Last modified: | 2021-04-14 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structure of the human Mediator-bound transcription preinitiation complex. Science, 372, 2021
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5SVA
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![BU of 5sva by Molmil](/molmil-images/mine/5sva) | Mediator-RNA Polymerase II Pre-Initiation Complex | Descriptor: | 108bp HIS4 Promoter Non-template Strand (-92/+16), 108bp HIS4 Promoter Template Strand (+16/-92), DNA repair helicase RAD25, ... | Authors: | Robinson, P.J, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2016-08-05 | Release date: | 2016-09-28 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (15.3 Å) | Cite: | Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex. Cell, 166, 2016
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8GXS
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![BU of 8gxs by Molmil](/molmil-images/mine/8gxs) | PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X. | Deposit date: | 2022-09-21 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
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8GXQ
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![BU of 8gxq by Molmil](/molmil-images/mine/8gxq) | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y. | Deposit date: | 2022-09-21 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (5.04 Å) | Cite: | Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
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4V1O
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![BU of 4v1o by Molmil](/molmil-images/mine/4v1o) | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | Deposit date: | 2014-09-29 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
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4V1N
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![BU of 4v1n by Molmil](/molmil-images/mine/4v1n) | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | Deposit date: | 2014-09-29 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
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3K7A
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![BU of 3k7a by Molmil](/molmil-images/mine/3k7a) | Crystal Structure of an RNA polymerase II-TFIIB complex | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Liu, X, Bushnell, D.A, Wang, D, Calero, G, Kornberg, R.D. | Deposit date: | 2009-10-12 | Release date: | 2009-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism. Science, 327, 2010
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3K1F
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![BU of 3k1f by Molmil](/molmil-images/mine/3k1f) | Crystal structure of RNA Polymerase II in complex with TFIIB | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Kostrewa, D, Zeller, M.E, Armache, K.-J, Seizl, M, Leike, K, Thomm, M, Cramer, P. | Deposit date: | 2009-09-27 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | RNA polymerase II-TFIIB structure and mechanism of transcription initiation. Nature, 462, 2009
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5OQM
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![BU of 5oqm by Molmil](/molmil-images/mine/5oqm) | STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH AND CORE MEDIATOR | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Urlaub, H, Cramer, P. | Deposit date: | 2017-08-13 | Release date: | 2018-05-09 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature, 551, 2017
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5OQJ
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![BU of 5oqj by Molmil](/molmil-images/mine/5oqj) | STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH | Descriptor: | DNA repair helicase RAD25, DNA repair helicase RAD3, DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Henning, U, Cramer, P. | Deposit date: | 2017-08-11 | Release date: | 2018-04-25 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature, 551, 2017
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7UIF
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![BU of 7uif by Molmil](/molmil-images/mine/7uif) | Mediator-PIC Early (Core B) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | Deposit date: | 2022-03-29 | Release date: | 2023-02-15 | Last modified: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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7UIO
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![BU of 7uio by Molmil](/molmil-images/mine/7uio) | Mediator-PIC Early (Composite Model) | Descriptor: | ALANINE, ASPARTIC ACID, DNA (37-MER), ... | Authors: | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | Deposit date: | 2022-03-29 | Release date: | 2023-03-01 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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7UI9
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![BU of 7ui9 by Molmil](/molmil-images/mine/7ui9) | Core Mediator-PICearly (Copy A) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | Deposit date: | 2022-03-28 | Release date: | 2023-02-15 | Last modified: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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6GYK
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![BU of 6gyk by Molmil](/molmil-images/mine/6gyk) | Structure of a yeast closed complex (core CC1) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | Deposit date: | 2018-06-30 | Release date: | 2018-12-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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6GYL
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![BU of 6gyl by Molmil](/molmil-images/mine/6gyl) | Structure of a yeast closed complex with distorted DNA (core CCdist) | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | Deposit date: | 2018-06-30 | Release date: | 2018-12-05 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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