2J5C
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![BU of 2j5c by Molmil](/molmil-images/mine/2j5c) | Rational conversion of substrate and product specificity in a monoterpene synthase. Structural insights into the molecular basis of rapid evolution. | Descriptor: | 1,8-CINEOLE SYNTHASE, BETA-MERCAPTOETHANOL | Authors: | Kampranis, S.C, Ioannidis, D, Purvis, A, Mahrez, W, Ninga, E, Katerelos, N.A, Anssour, S, Dunwell, J.M, Makris, A.M, Goodenough, P.W, Johnson, C.B. | Deposit date: | 2006-09-14 | Release date: | 2007-06-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Rational Conversion of Substrate and Product Specificity in a Salvia Monoterpene Synthase: Structural Insights Into the Evolution of Terpene Synthase Function. Plant Cell, 19, 2007
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4FJQ
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![BU of 4fjq by Molmil](/molmil-images/mine/4fjq) | Crystal Structure of an alpha-Bisabolol synthase | Descriptor: | Amorpha-4,11-diene synthase | Authors: | Jianxu, L, Peng, Z. | Deposit date: | 2012-06-12 | Release date: | 2013-03-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.0001 Å) | Cite: | Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. Biochem.J., 451, 2013
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5JO7
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![BU of 5jo7 by Molmil](/molmil-images/mine/5jo7) | Henbane premnaspirodiene synthase (HPS), also known as Henbane vetispiradiene synthase (HVS) from Hyoscyamus muticus | Descriptor: | Vetispiradiene synthase 1 | Authors: | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | Deposit date: | 2016-05-02 | Release date: | 2017-05-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Functional study of terpene synthase from 512 mutant library of henbane premnaspirodiene synthase reveals protein residue interactions To Be Published
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6K16
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7Y47
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![BU of 7y47 by Molmil](/molmil-images/mine/7y47) | Crystal structure of bifunctional miltiradiene synthase from selaginella moellendorffii that complexed with GGPP | Descriptor: | Bifunctional diterpene synthase, chloroplastic, GERANYLGERANYL DIPHOSPHATE, ... | Authors: | Ma, X, Tao, Y, Jiang, T. | Deposit date: | 2022-06-14 | Release date: | 2022-10-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and mechanistic insights into the precise product synthesis by a bifunctional miltiradiene synthase. Plant Biotechnol J, 21, 2023
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4GAX
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![BU of 4gax by Molmil](/molmil-images/mine/4gax) | Crystal Structure of an alpha-Bisabolol synthase mutant | Descriptor: | Amorpha-4,11-diene synthase | Authors: | Li, J, Peng, Z. | Deposit date: | 2012-07-26 | Release date: | 2013-03-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9948 Å) | Cite: | Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. Biochem.J., 451, 2013
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4DI5
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5C05
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![BU of 5c05 by Molmil](/molmil-images/mine/5c05) | Crystal Structure of Gamma-terpinene Synthase from Thymus vulgaris | Descriptor: | 1,2-ETHANEDIOL, Putative gamma-terpinene synthase | Authors: | Parthier, C.P, Rudolph, K, Muller, Y.A, Mueller-Uri, F. | Deposit date: | 2015-06-12 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Expression, crystallization and structure elucidation of gamma-terpinene synthase from Thymus vulgaris. Acta Crystallogr.,Sect.F, 72, 2016
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7WAT
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4RNQ
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![BU of 4rnq by Molmil](/molmil-images/mine/4rnq) | Crystal structure of tobacco 5-epi-aristolochene synthase (TEAS) with anilinogeranyl diphosphate (AGPP) and geraniline | Descriptor: | (2E,6E)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl trihydrogen diphosphate, 5-epi-aristolochene synthase, ACETATE ION, ... | Authors: | Koo, H.J, Crenshaw, C.M, Starks, C, Spielmann, H.P, Chappell, J, Noel, J.P. | Deposit date: | 2014-10-24 | Release date: | 2015-05-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Formation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase. Acs Chem.Biol., 10, 2015
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5DHI
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5DHK
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7BZB
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7BZC
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![BU of 7bzc by Molmil](/molmil-images/mine/7bzc) | Crystal structure of plant sesterterpene synthase AtTPS18 complexed with farnesyl thiolodiphosphate (FSPP) | Descriptor: | MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, Terpenoid synthase 18 | Authors: | Li, J.X, Wang, G.D, Zhang, P. | Deposit date: | 2020-04-27 | Release date: | 2020-09-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.303 Å) | Cite: | Molecular Basis for Sesterterpene Diversity Produced by Plant Terpene Synthases. Plant Commun., 1, 2020
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2ONH
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![BU of 2onh by Molmil](/molmil-images/mine/2onh) | Crystal Structure of of limonene synthase with 2-fluorolinalyl diphosphate(FLPP) | Descriptor: | (1S)-1-[(1S)-1-FLUOROETHYL]-1,5-DIMETHYLHEXYL TRIHYDROGEN DIPHOSPHATE, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4S-limonene synthase, ... | Authors: | Hyatt, D.C, Youn, B, Croteau, R, Kang, C. | Deposit date: | 2007-01-24 | Release date: | 2007-03-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of limonene synthase, a simple model for terpenoid cyclase catalysis. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2ONG
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![BU of 2ong by Molmil](/molmil-images/mine/2ong) | Crystal Structure of of limonene synthase with 2-fluorogeranyl diphosphate (FGPP). | Descriptor: | (1S)-1-[(1R)-1-FLUOROETHYL]-1,5-DIMETHYLHEXYL TRIHYDROGEN DIPHOSPHATE, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4S-limonene synthase, ... | Authors: | Hyatt, D.C, Youn, B, Croteau, R, Kang, C. | Deposit date: | 2007-01-23 | Release date: | 2007-03-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of limonene synthase, a simple model for terpenoid cyclase catalysis. Proc.Natl.Acad.Sci.Usa, 104, 2007
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3G4D
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![BU of 3g4d by Molmil](/molmil-images/mine/3g4d) | Crystal Structure of (+)-delta-Cadinene Synthase from Gossypium arboreum and Evolutionary Divergence of Metal Binding Motifs for Catalysis | Descriptor: | (+)-delta-cadinene synthase isozyme XC1, BETA-MERCAPTOETHANOL, GLYCEROL | Authors: | Gennadios, H.A, Di Costanzo, L, Miller, D.J, Allemann, R.K, Christianson, D.W. | Deposit date: | 2009-02-03 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry, 48, 2009
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3G4F
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![BU of 3g4f by Molmil](/molmil-images/mine/3g4f) | Crystal Structure of (+)- -Cadinene Synthase from Gossypium arboreum in complex with 2-fluorofarnesyl diphosphate | Descriptor: | (+)-delta-cadinene synthase isozyme XC1, (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, BETA-MERCAPTOETHANOL, ... | Authors: | Gennadios, H.A, Di Costanzo, L, Christianson, D.W. | Deposit date: | 2009-02-03 | Release date: | 2009-06-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.651 Å) | Cite: | Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry, 48, 2009
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6O9P
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![BU of 6o9p by Molmil](/molmil-images/mine/6o9p) | Wild-type SaSQS1 Complexed with Ibandronate | Descriptor: | 1,2-ETHANEDIOL, IBANDRONATE, MAGNESIUM ION, ... | Authors: | Blank, P.N, Christianson, D.W. | Deposit date: | 2019-03-14 | Release date: | 2019-04-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Sesquisabinene Synthase 1, a Terpenoid Cyclase That Generates a Strained [3.1.0] Bridged-Bicyclic Product. Acs Chem.Biol., 14, 2019
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6O9Q
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![BU of 6o9q by Molmil](/molmil-images/mine/6o9q) | Wild-type SaSQS1 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Sesquisabinene B synthase 1 | Authors: | Blank, P.N, Christianson, D.W. | Deposit date: | 2019-03-14 | Release date: | 2019-04-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of Sesquisabinene Synthase 1, a Terpenoid Cyclase That Generates a Strained [3.1.0] Bridged-Bicyclic Product. Acs Chem.Biol., 14, 2019
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5EAU
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![BU of 5eau by Molmil](/molmil-images/mine/5eau) | 5-EPI-ARISTOLOCHENE SYNTHASE FROM NICOTIANA TABACUM | Descriptor: | 5-EPI-ARISTOLOCHENE SYNTHASE, MAGNESIUM ION, TRIFLUOROFURNESYL DIPHOSPHATE | Authors: | Starks, C.M, Back, K, Chappell, J, Noel, J.P. | Deposit date: | 1997-12-11 | Release date: | 1998-04-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase. Science, 277, 1997
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1N20
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![BU of 1n20 by Molmil](/molmil-images/mine/1n20) | (+)-Bornyl Diphosphate Synthase: Complex with Mg and 3-aza-2,3-dihydrogeranyl diphosphate | Descriptor: | (+)-bornyl diphosphate synthase, 2-[METHYL-(4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, MAGNESIUM ION | Authors: | Whittington, D.A, Wise, M.L, Urbansky, M, Coates, R.M, Croteau, R.B, Christianson, D.W. | Deposit date: | 2002-10-21 | Release date: | 2002-11-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Bornyl Diphosphate Synthase: Structure and Strategy for Carbocation Manipulation by a Terpenoid Cyclase Proc.Natl.Acad.Sci.USA, 99, 2002
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1N1B
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![BU of 1n1b by Molmil](/molmil-images/mine/1n1b) | Crystal Structure of (+)-Bornyl Diphosphate Synthase from Sage | Descriptor: | (+)-bornyl diphosphate synthase, MAGNESIUM ION, MERCURY (II) ION | Authors: | Whittington, D.A, Wise, M.L, Urbansky, M, Coates, R.M, Croteau, R.B, Christianson, D.W. | Deposit date: | 2002-10-17 | Release date: | 2002-11-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Bornyl Diphosphate Synthase: Structure and Strategy for Carbocation Manipulation by a Terpenoid Cyclase Proc.Natl.Acad.Sci.USA, 99, 2002
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1N22
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![BU of 1n22 by Molmil](/molmil-images/mine/1n22) | (+)-Bornyl Diphosphate Synthase: Complex with Mg, pyrophosphate, and (4R)-7-aza-7,8-dihydrolimonene | Descriptor: | (+)-bornyl diphosphate synthase, (1R)-DIMETHYL-(4-METHYL-CYCLOHEX-3-ENYL)-AMINE, MAGNESIUM ION, ... | Authors: | Whittington, D.A, Wise, M.L, Urbansky, M, Coates, R.M, Croteau, R.B, Christianson, D.W. | Deposit date: | 2002-10-21 | Release date: | 2002-11-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase Proc.Natl.Acad.Sci.USA, 99, 2002
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7CJY
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