6SZD
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![BU of 6szd by Molmil](/molmil-images/mine/6szd) | Hydrogenase-2 variant R479K - hydrogen reduced form | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... | Authors: | Carr, S.B, Beaton, S.E, Evans, R.M, Armstrong, F.A. | Deposit date: | 2019-10-02 | Release date: | 2020-10-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Hydrogen activation by NiFe-hydrogenases - consolidating the role of the pendant arginine. To Be Published
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6SZK
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![BU of 6szk by Molmil](/molmil-images/mine/6szk) | Hydrogenase-2 variant R479K - hydrogen reduced form treated with CO | Descriptor: | CARBON MONOXIDE, CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, ... | Authors: | Carr, S.B, Beaton, S.E, Evans, R.M, Armstrong, F.A. | Deposit date: | 2019-10-02 | Release date: | 2020-10-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Hydrogen activation by NiFe-hydrogenases - consolidating the role of the pendant arginine. To Be Published
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6SYX
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![BU of 6syx by Molmil](/molmil-images/mine/6syx) | Hydrogenase-2 variant R479K - reduced sample exposed to pure oxygen | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... | Authors: | Carr, S.B, Beaton, S.E, Evans, R.M, Armstrong, F.A. | Deposit date: | 2019-10-01 | Release date: | 2020-10-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Hydrogen activation by NiFe-hydrogenases - consolidating the role of the pendant arginine. To Be Published
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6QGR
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![BU of 6qgr by Molmil](/molmil-images/mine/6qgr) | The F420-reducing [NiFe] hydrogenase complex from Methanosarcina barkeri at the Nia-S state | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, (R,R)-2,3-BUTANEDIOL, Coenzyme F420 hydrogenase subunit alpha, ... | Authors: | Ilina, Y, Lorent, C, Katz, S, Jeoung, J.H, Shima, S, Horch, M, Zebger, I, Dobbek, H. | Deposit date: | 2019-01-12 | Release date: | 2019-10-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.839 Å) | Cite: | X-ray Crystallography and Vibrational Spectroscopy Reveal the Key Determinants of Biocatalytic Dihydrogen Cycling by [NiFe] Hydrogenases. Angew.Chem.Int.Ed.Engl., 58, 2019
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4UE3
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![BU of 4ue3 by Molmil](/molmil-images/mine/4ue3) | The Mechanism of Hydrogen Activation by NiFe-hydrogenases and the Importance of the active site Arginine | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... | Authors: | Evans, R.M, Wehlin, S.A.M, Nomerotskaia, E, Sargent, F, Carr, S.B, Phillips, S.E.V, Armstrong, F.A. | Deposit date: | 2014-12-15 | Release date: | 2014-12-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Mechanism of Hydrogen Activation by [Nife] Hydrogenases. Nat.Chem.Biol., 12, 2016
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6U8Y
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![BU of 6u8y by Molmil](/molmil-images/mine/6u8y) | |
2YBB
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![BU of 2ybb by Molmil](/molmil-images/mine/2ybb) | Fitted model for bovine mitochondrial supercomplex I1III2IV1 by single particle cryo-EM (EMD-1876) | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, CARDIOLIPIN, ... | Authors: | Althoff, T, Mills, D.J, Popot, J.-L, Kuehlbrandt, W. | Deposit date: | 2011-03-02 | Release date: | 2011-10-19 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (19 Å) | Cite: | Arrangement of Electron Transport Chain Components in Bovine Mitochondrial Supercomplex I(1)III(2)Iv(1). Embo J., 30, 2011
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2WPN
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![BU of 2wpn by Molmil](/molmil-images/mine/2wpn) | Structure of the oxidised, as-isolated NiFeSe hydrogenase from D. vulgaris Hildenborough | Descriptor: | 3-[DODECYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, BIS-(MU-2-OXO),[(MU-3--SULFIDO)-BIS(MU-2--SULFIDO)-TRIS(CYS-S)-TRI-IRON] (AQUA)(GLU-O)IRON(II), CARBONMONOXIDE-(DICYANO) IRON, ... | Authors: | Marques, M.C, Coelho, R, De Lacey, A.L, Pereira, I.A.C, Matias, P.M. | Deposit date: | 2009-08-07 | Release date: | 2010-01-12 | Last modified: | 2019-07-10 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | The three-dimensional structure of [NiFeSe] hydrogenase from Desulfovibrio vulgaris Hildenborough: a hydrogenase without a bridging ligand in the active site in its oxidised, "as-isolated" state. J.Mol.Biol., 396, 2010
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4WZ7
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![BU of 4wz7 by Molmil](/molmil-images/mine/4wz7) | Crystal structure of mitochondrial NADH:ubiquinone oxidoreductase from Yarrowia lipolytica. | Descriptor: | 39-kDa subunit, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, ... | Authors: | Wirth, C, Zickermann, V, Brandt, U, Hunte, C. | Deposit date: | 2014-11-18 | Release date: | 2015-03-25 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural biology. Mechanistic insight from the crystal structure of mitochondrial complex I. Science, 347, 2015
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3RGW
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![BU of 3rgw by Molmil](/molmil-images/mine/3rgw) | Crystal structure at 1.5 A resolution of an H2-reduced, O2-tolerant hydrogenase from Ralstonia eutropha unmasks a novel iron-sulfur cluster | Descriptor: | FE3-S4 CLUSTER, FE4-S3 CLUSTER, IRON/SULFUR CLUSTER, ... | Authors: | Scheerer, P, Fritsch, J, Frielingsdorf, S, Kroschinsky, S, Friedrich, B, Lenz, O, Spahn, C.M.T. | Deposit date: | 2011-04-10 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre. Nature, 479, 2011
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6CFW
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![BU of 6cfw by Molmil](/molmil-images/mine/6cfw) | |
4KL8
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![BU of 4kl8 by Molmil](/molmil-images/mine/4kl8) | High-resolution structure of anaerobically purified Dm. baculatum [NiFeSe]-hydrogenase after crystallization under air | Descriptor: | CALCIUM ION, CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, ... | Authors: | Volbeda, A, Cavazza, C, Fontecilla-Camps, J.C. | Deposit date: | 2013-05-07 | Release date: | 2013-07-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Structural foundations for the O2 resistance of Desulfomicrobium baculatum [NiFeSe]-hydrogenase. Chem.Commun.(Camb.), 49, 2013
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4KO1
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![BU of 4ko1 by Molmil](/molmil-images/mine/4ko1) | High X-ray dose structure of H2-activated anaerobically purified Dm. baculatum [NiFeSe]-hydrogenase after crystallization under air | Descriptor: | CALCIUM ION, CARBONMONOXIDE-(DICYANO) IRON, GLYCEROL, ... | Authors: | Volbeda, A, Cavazza, C, Fontecilla-Camps, J.C. | Deposit date: | 2013-05-11 | Release date: | 2013-07-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural foundations for the O2 resistance of Desulfomicrobium baculatum [NiFeSe]-hydrogenase. Chem.Commun.(Camb.), 49, 2013
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8ESW
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![BU of 8esw by Molmil](/molmil-images/mine/8esw) | Structure of mitochondrial complex I from Drosophila melanogaster, Flexible-class 1 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Padavannil, A, Letts, J.A. | Deposit date: | 2022-10-15 | Release date: | 2023-03-29 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state. Elife, 12, 2023
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8ESZ
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![BU of 8esz by Molmil](/molmil-images/mine/8esz) | Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state | Descriptor: | (2R)-3-{[(S)-hydroxy(3-methylbutoxy)phosphoryl]oxy}-2-(octanoyloxy)propyl decanoate, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | Authors: | Padavannil, A, Letts, J.A. | Deposit date: | 2022-10-15 | Release date: | 2023-03-29 | Last modified: | 2023-04-05 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state. Elife, 12, 2023
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4OMF
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![BU of 4omf by Molmil](/molmil-images/mine/4omf) | The F420-reducing [NiFe]-hydrogenase complex from Methanothermobacter marburgensis, the first X-ray structure of a group 3 family member | Descriptor: | CHLORIDE ION, F420-reducing hydrogenase, subunit alpha, ... | Authors: | Vitt, S, Ma, K, Warkentin, E, Moll, J, Pierik, A, Shima, S, Ermler, U. | Deposit date: | 2014-01-27 | Release date: | 2014-06-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | The F420-Reducing [NiFe]-Hydrogenase Complex from Methanothermobacter marburgensis, the First X-ray Structure of a Group 3 Family Member. J.Mol.Biol., 426, 2014
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3MYR
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![BU of 3myr by Molmil](/molmil-images/mine/3myr) | Crystal structure of [NiFe] hydrogenase from Allochromatium vinosum in its Ni-A state | Descriptor: | CHLORIDE ION, FE3-S4 CLUSTER, Hydrogenase (NiFe) small subunit HydA, ... | Authors: | Ogata, H, Kellers, P, Lubitz, W. | Deposit date: | 2010-05-11 | Release date: | 2010-08-04 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of the [NiFe] hydrogenase from the photosynthetic bacterium Allochromatium vinosum: characterization of the oxidized enzyme (Ni-A state). J.Mol.Biol., 402, 2010
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5AA5
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![BU of 5aa5 by Molmil](/molmil-images/mine/5aa5) | Actinobacterial-type NiFe-hydrogenase from Ralstonia eutropha H16 at 2.85 Angstrom resolution | Descriptor: | IRON/SULFUR CLUSTER, MALONIC ACID, NIFE-HYDROGENASE LARGE SUBUNIT, ... | Authors: | Schaefer, C, Bommer, M, Hennig, S, Jeoung, J.H, Dobbek, H, Lenz, O. | Deposit date: | 2015-07-23 | Release date: | 2016-01-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | Structure of an Actinobacterial-Type [Nife]-Hydrogenase Reveals Insight Into O2-Tolerant H2 Oxidation. Structure, 24, 2016
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4UQP
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![BU of 4uqp by Molmil](/molmil-images/mine/4uqp) | High-resolution structure of the D. fructosovorans NiFe-hydrogenase L122A mutant after exposure to air | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, GLYCEROL, ... | Authors: | Volbeda, A, Martin, L, Barbier, E, Gutierrez-Sanz, O, DeLacey, A.L, Liebgott, P.P, Dementin, S, Rousset, M, Fontecilla-Camps, J.C. | Deposit date: | 2014-06-24 | Release date: | 2014-10-29 | Last modified: | 2023-03-15 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Crystallographic Studies of [Nife]-Hydrogenase Mutants: Towards Consensus Structures for the Elusive Unready Oxidized States. J.Biol.Inorg.Chem., 20, 2015
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4UQL
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![BU of 4uql by Molmil](/molmil-images/mine/4uql) | High-resolution structure of a Ni-A Ni-Sox mixture of the D. fructosovorans NiFe-hydrogenase L122A mutant | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... | Authors: | Volbeda, A, Martin, L, Barbier, E, Gutierrez-Sanz, O, DeLacey, A.L, Liebgott, P.P, Dementin, S, Rousset, M, Fontecilla-Camps, J.C. | Deposit date: | 2014-06-24 | Release date: | 2014-10-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Crystallographic Studies of [Nife]-Hydrogenase Mutants: Towards Consensus Structures for the Elusive Unready Oxidized States. J.Biol.Inorg.Chem., 20, 2015
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5A4F
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![BU of 5a4f by Molmil](/molmil-images/mine/5a4f) | The mechanism of Hydrogen Activation by NiFe-hydrogenases. | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... | Authors: | Evans, R.M, Brooke, E.J, Wehlin, S.A.M, Nomerotskaia, E, Sargent, F, Carr, S.B, Phillips, S.E.V, Armstrong, F.A. | Deposit date: | 2015-06-09 | Release date: | 2015-11-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Mechanism of hydrogen activation by [NiFe] hydrogenases. Nat. Chem. Biol., 12, 2016
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8GYM
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![BU of 8gym by Molmil](/molmil-images/mine/8gym) | Cryo-EM structure of Tetrahymena thermophila respiratory mega-complex MC IV2+(I+III2+II)2 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | Authors: | Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L. | Deposit date: | 2022-09-23 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae. Nat Commun, 14, 2023
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8GZU
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![BU of 8gzu by Molmil](/molmil-images/mine/8gzu) | Cryo-EM structure of Tetrahymena thermophila respiratory Megacomplex MC (IV2+I+III2+II)2 | Descriptor: | 2 iron, 2 sulfur cluster-binding protein, 2-oxoglutarate/malate carrier protein, ... | Authors: | Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L. | Deposit date: | 2022-09-27 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae. Nat Commun, 14, 2023
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4C3O
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![BU of 4c3o by Molmil](/molmil-images/mine/4c3o) | Structure and function of an oxygen tolerant NiFe hydrogenase from Salmonella | Descriptor: | CHLORIDE ION, FE3-S4 CLUSTER, FE4-S3 CLUSTER, ... | Authors: | Bowman, L, Flanagan, L, Fyfe, P.K, Parkin, A, Hunter, W.N, Sargent, F. | Deposit date: | 2013-08-26 | Release date: | 2014-01-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | How the Structure of the Large Subunit Controls Function in an Oxygen-Tolerant [Nife]-Hydrogenase. Biochem.J., 458, 2014
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1CC1
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![BU of 1cc1 by Molmil](/molmil-images/mine/1cc1) | CRYSTAL STRUCTURE OF A REDUCED, ACTIVE FORM OF THE NI-FE-SE HYDROGENASE FROM DESULFOMICROBIUM BACULATUM | Descriptor: | CARBONMONOXIDE-(DICYANO) IRON, FE (II) ION, HYDROGENASE (LARGE SUBUNIT), ... | Authors: | Garcin, E, Vernede, X, Hatchikian, E.C, Volbeda, A, Frey, M, Fontecilla-Camps, J.C. | Deposit date: | 1999-03-03 | Release date: | 1999-06-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The crystal structure of a reduced [NiFeSe] hydrogenase provides an image of the activated catalytic center Structure Fold.Des., 7, 1999
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