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7BET
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BU of 7bet by Molmil
Structure of Ribonucleotide reductase R2 from Escherichia coli collected by femtosecond serial crystallography on a COC membrane
Descriptor: FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit beta
Authors:Aurelius, O, John, J, Martiel, I, Marsh, M, Vera, L, Huang, C.Y, Olieric, V, Leonarski, P, Nass, K, Padeste, C, Karpik, A, Hogbom, M, Wang, M, Pedrini, B.
Deposit date:2020-12-24
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Commissioning results from the SwissMX instrument for fixed target macromolecular crystallography at SwissFEL
To Be Published
5DCO
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BU of 5dco by Molmil
R2-like ligand-binding oxidase with aerobically reconstituted diiron cofactor (short soak)
Descriptor: FE (III) ION, PALMITIC ACID, Ribonucleotide reductase small subunit
Authors:Griese, J.J, Hogbom, M.
Deposit date:2015-08-24
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.326 Å)
Cite:Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor.
J.Biol.Chem., 290, 2015
2VUX
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BU of 2vux by Molmil
Human ribonucleotide reductase, subunit M2 B
Descriptor: FE (III) ION, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 B
Authors:Welin, M, Moche, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Svensson, L, Thorsell, A.G, Tresaugues, L, van Den Berg, S, Weigelt, J, Wikstrom, M, Nordlund, P, Structural Genomics Consortium (SGC)
Deposit date:2008-05-31
Release date:2008-07-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human Ribonucleotide Reductase, Subunit M2 B
To be Published
7QBP
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BU of 7qbp by Molmil
Crystal structure of R2-like ligand-binding oxidase from Saccharopolyspora Erythraea
Descriptor: FE (III) ION, MANGANESE (III) ION, PALMITIC ACID, ...
Authors:Srinivas, V, Diamanti, R, Lebrette, H, Hogbom, M.
Deposit date:2021-11-19
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Comparative structural analysis provides new insights into the function of R2-like ligand-binding oxidase.
Febs Lett., 596, 2022
7QBK
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BU of 7qbk by Molmil
Crystal structure of a second homolog of R2-like ligand-binding oxidase in Sulfolobus acidocaldarius (SaR2loxII)
Descriptor: FE (III) ION, MANGANESE (III) ION, R2-like ligand-binding oxidase (homolog II) from Sulfolobus acidocaldarius
Authors:Lebrette, H, Diamanti, R, Srinivas, V, Hogbom, M.
Deposit date:2021-11-19
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Comparative structural analysis provides new insights into the function of R2-like ligand-binding oxidase.
Febs Lett., 596, 2022
1AV8
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BU of 1av8 by Molmil
RIBONUCLEOTIDE REDUCTASE R2 SUBUNIT FROM E. COLI
Descriptor: MU-OXO-DIIRON, RIBONUCLEOTIDE REDUCTASE R2
Authors:Han, S, Arvai, A, Tainer, J.A.
Deposit date:1997-09-30
Release date:1998-10-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Characterization of Y122F R2 of Escherichia coli ribonucleotide reductase by time-resolved physical biochemical methods and X-ray crystallography.
Biochemistry, 37, 1998
5EKB
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BU of 5ekb by Molmil
R2-like ligand-binding oxidase with aerobically reconstituted Mn/Fe cofactor (reconstituted in solution)
Descriptor: FE (III) ION, MANGANESE (III) ION, PALMITIC ACID, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2015-11-03
Release date:2016-04-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.074 Å)
Cite:Divergent assembly mechanisms of the manganese/iron cofactors in R2lox and R2c proteins.
J.Inorg.Biochem., 162, 2016
1BIQ
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BU of 1biq by Molmil
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN MUTANT E238A
Descriptor: FE (II) ION, FE (III) ION, HYDROXIDE ION, ...
Authors:Logan, D.T, Demare, F, Persson, B.O, Slaby, A, Sjoberg, B.M, Nordlund, P.
Deposit date:1998-06-18
Release date:1999-01-13
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of two self-hydroxylating ribonucleotide reductase protein R2 mutants: structural basis for the oxygen-insertion step of hydroxylation reactions catalyzed by diiron proteins.
Biochemistry, 37, 1998
2XOF
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BU of 2xof by Molmil
Ribonucleotide reductase Y122NO2Y modified R2 subunit of E. coli
Descriptor: MU-OXO-DIIRON, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA
Authors:Yokoyama, K, Uhlin, U, Stubbe, J.
Deposit date:2010-08-15
Release date:2010-08-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Hot Oxidant, 3-No(2)Y(122) Radical, Unmasks Conformational Gating in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
3DHZ
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BU of 3dhz by Molmil
Apo (iron free) structure of C. ammoniagenes R2 protein
Descriptor: FE (II) ION, Ribonucleotide reductase subunit R2F
Authors:Hogbom, M, Nordlund, P.
Deposit date:2008-06-19
Release date:2008-07-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural and mutational studies of the carboxylate cluster in Iron-free Ribonucleotide Reductase R2.
Biochemistry, 43, 2004
3EE4
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BU of 3ee4 by Molmil
R2-like ligand binding Mn/Fe oxidase from M. tuberculosis
Descriptor: FE (III) ION, MANGANESE (III) ION, MYRISTIC ACID, ...
Authors:Andersson, C.S, Jones, T.A, Hogbom, M.
Deposit date:2008-09-04
Release date:2009-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Mycobacterium tuberculosis ligand-binding Mn/Fe protein reveals a new cofactor in a remodeled R2-protein scaffold
Proc.Natl.Acad.Sci.Usa, 106, 2009
6Y2N
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BU of 6y2n by Molmil
Crystal structure of ribonucleotide reductase R2 subunit solved by serial synchrotron crystallography
Descriptor: FE (III) ION, MANGANESE (III) ION, Ribonucleoside-diphosphate reductase subunit beta
Authors:Shilova, A, Lebrette, H, Aurelius, O, Hogbom, M, Mueller, U.
Deposit date:2020-02-17
Release date:2020-10-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Current status and future opportunities for serial crystallography at MAX IV Laboratory.
J.Synchrotron Radiat., 27, 2020
1H0N
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BU of 1h0n by Molmil
Cobalt substitution of mouse R2 ribonucleotide reductase to model the reactive diferrous state
Descriptor: COBALT (II) ION, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE
Authors:Strand, K.R, Karlsen, S, Andersson, K.K.
Deposit date:2002-06-26
Release date:2002-07-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Cobalt Substitution of Mouse R2 Ribonucleotide Reductase as a Model for Thereactive Diferrous State. Spectroscopic and Structural Evidence for a Ferromagnetically Coupled Dinuclear Cobalt Cluster
J.Biol.Chem., 277, 2002
1H0O
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BU of 1h0o by Molmil
Cobalt substitution of mouse R2 ribonucleotide reductase to model the reactive diferrous state
Descriptor: COBALT (II) ION, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE
Authors:Strand, K.R, Karlsen, S, Andersson, K.K.
Deposit date:2002-06-26
Release date:2002-07-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cobalt Substitution of Mouse R2 Ribonucleotide Reductase as a Model for Thereactive Diferrous State. Spectroscopic and Structural Evidence for a Ferromagnetically Coupled Dinuclear Cobalt Cluster
J.Biol.Chem., 277, 2002
3HF1
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BU of 3hf1 by Molmil
Crystal structure of human p53R2
Descriptor: FE (III) ION, Ribonucleoside-diphosphate reductase subunit M2 B, SULFATE ION
Authors:Smith, P, Zhou, B, Yuan, Y.-C, Su, L, Tsai, S.-C, Yen, Y.
Deposit date:2009-05-10
Release date:2009-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:2.6 A X-ray crystal structure of human p53R2, a p53-inducible ribonucleotide reductase .
Biochemistry, 48, 2009
4XB9
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BU of 4xb9 by Molmil
R2-like ligand-binding oxidase with aerobically reconstituted diiron cofactor
Descriptor: FE (III) ION, PALMITIC ACID, Ribonuleotide reductase small subunit
Authors:Griese, J.J, Hogbom, M.
Deposit date:2014-12-16
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor.
J.Biol.Chem., 290, 2015
4HR4
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BU of 4hr4 by Molmil
R2-like ligand-binding oxidase with anaerobically reconstituted metal cofactor
Descriptor: FE (II) ION, MANGANESE (II) ION, PALMITIC ACID, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2012-10-26
Release date:2013-10-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein
Proc.Natl.Acad.Sci.USA, 110, 2013
8DQ4
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BU of 8dq4 by Molmil
X-ray crystal structure of Flavobacterium johnsoniae dimanganese(II) class Id ribonucleotide reductase beta subunit K71R variant
Descriptor: GLYCEROL, MANGANESE (II) ION, Ribonucleoside-diphosphate reductase
Authors:Rose, H.R, Maggiolo, A.O, Jung, J.J, Boal, A.K.
Deposit date:2022-07-18
Release date:2023-07-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:X-ray crystal structure of Flavobacterium johnsoniae dimanganese(II) class Id ribonucleotide reductase beta subunit K71R variant
To Be Published
8DQ5
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BU of 8dq5 by Molmil
X-ray crystal structure of Flavobacterium johnsoniae dimanganese(II) class Id ribonucleotide reductase T191I variant
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, Ribonucleoside-diphosphate reductase
Authors:Rose, H.R, Boal, A.K.
Deposit date:2022-07-18
Release date:2023-07-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray crystal structure of Flavobacterium johnsoniae dimanganese(II) class Id ribonucleotide reductase T191I variant
To Be Published
4HR5
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BU of 4hr5 by Molmil
R2-like ligand-binding oxidase without metal cofactor
Descriptor: PALMITIC ACID, Ribonuleotide reductase small subunit
Authors:Griese, J.J, Hogbom, M.
Deposit date:2012-10-26
Release date:2013-10-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.291 Å)
Cite:Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein
Proc.Natl.Acad.Sci.USA, 110, 2013
8DQ3
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BU of 8dq3 by Molmil
X-ray crystal structure of Aggregatibacter actinomycetemcomitans dimanganese(II) class Id ribonucleotide reductase beta subunit
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, MAGNESIUM ION, ...
Authors:Rose, H.R, Jung, J.J, Boal, A.K.
Deposit date:2022-07-18
Release date:2023-07-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:X-ray crystal structure of Aggregatibacter actinomycetemcomitans dimanganese(II) class Id ribonucleotide reductase beta subunit
To Be Published
4HR0
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BU of 4hr0 by Molmil
R2-like ligand-binding oxidase with aerobically reconstituted metal cofactor
Descriptor: FE (III) ION, MANGANESE (II) ION, MANGANESE (III) ION, ...
Authors:Griese, J.J, Hogbom, M.
Deposit date:2012-10-26
Release date:2013-10-16
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (1.896 Å)
Cite:Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein
Proc.Natl.Acad.Sci.USA, 110, 2013
4XBW
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BU of 4xbw by Molmil
R2-like ligand-binding oxidase with aerobically reconstituted dimanganese cofactor
Descriptor: MANGANESE (II) ION, PALMITIC ACID, Ribonucleotide reductase small subunit
Authors:Griese, J.J, Hogbom, M.
Deposit date:2014-12-17
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.991 Å)
Cite:Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor.
J.Biol.Chem., 290, 2015
4XBV
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BU of 4xbv by Molmil
R2-like ligand-binding oxidase with anaerobically reconstituted diiron cofactor
Descriptor: FE (II) ION, PALMITIC ACID, Ribonuleotide reductase small subunit
Authors:Griese, J.J, Hogbom, M.
Deposit date:2014-12-17
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor.
J.Biol.Chem., 290, 2015
5OMJ
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BU of 5omj by Molmil
R2-like ligand-binding oxidase with aerobically reconstituted metal cofactor after photoconversion
Descriptor: FE (III) ION, PALMITIC ACID, Ribonucleotide reductase small subunit
Authors:Griese, J.J, Hogbom, M.
Deposit date:2017-07-31
Release date:2018-01-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Driving Protein Conformational Changes with Light: Photoinduced Structural Rearrangement in a Heterobimetallic Oxidase.
J. Am. Chem. Soc., 140, 2018

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