PDB: 145 resultsInfo pagesStatus searchChemie searchBIRD

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4F8Z	Carboxypeptidase T with Boc-Leu Descriptor: CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... Authors: Timofeev, V.I, Kuznetsov, S.A, Akparov, V.K, Kuranova, I.P. Deposit date: 2012-05-18 Release date: 2013-05-22 Last modified: 2015-09-30 Method: X-RAY DIFFRACTION (1.38 Å) Cite: Three-dimensional structure of carboxypeptidase T from Thermoactinomyces vulgaris in complex with N-BOC-L-leucine. Biochemistry Mosc., 78, 2013
1M4L	STRUCTURE OF NATIVE CARBOXYPEPTIDASE A AT 1.25 RESOLUTION Descriptor: CARBOXYPEPTIDASE A, ZINC ION Authors: Kilshtain-Vardi, A, Glick, M, Greenblatt, H.M, Goldblum, A, Shoham, G. Deposit date: 2002-07-03 Release date: 2003-01-10 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Refined structure of bovine carboxypeptidase A at 1.25 A resolution. Acta Crystallogr.,Sect.D, 59, 2003
8CPA	COMPARISON OF THE STRUCTURES OF THREE CARBOXYPEPTIDASE A-PHOSPHONATE COMPLEXES DETERMINED BY X-RAY CRYSTALLOGRAPHY Descriptor: CARBOXYPEPTIDASE A, O-(((1R)-((N-(PHENYL-METHOXY-CARBONYL)-ALANYL)-AMINO)METHYL)HYDROXYPHOSPHINYL)3-L-PHENYLLACTATE, ZINC ION Authors: Kim, H, Lipscomb, W.N. Deposit date: 1991-05-21 Release date: 1994-01-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2 Å) Cite: Comparison of the structures of three carboxypeptidase A-phosphonate complexes determined by X-ray crystallography. Biochemistry, 30, 1991
7Q87	Carboxypeptidase T with (S)-3-phenyllactic acid Descriptor: ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID, CALCIUM ION, Carboxypeptidase T, ... Authors: Timofeev, V.I, Akparov, V.K, Shevtsov, M.B, Kuranova, I.P. Deposit date: 2021-11-10 Release date: 2022-01-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Carboxypeptidase T with (S)-3-phenyllactic acid To Be Published
6Z28	Carboxypeptidase T mutant L254N with N-sulfamoyl-L-glutamic acid Descriptor: CALCIUM ION, Carboxypeptidase T, N-sulfamoyl-L-glutamic acid, ... Authors: Timofeev, V.I, Akparov, V.K, Kuranova, I.P. Deposit date: 2020-05-15 Release date: 2020-05-27 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: CARBOXYPEPTIDASE T MUTANT L254N WITH WITH N-SULFAMOYL-L-GLUT To Be Published
8QVO	L211Q, L254N, T262G mutant of carboxypeptidase T from Thermoactinomyces vulgaris Descriptor: CALCIUM ION, Carboxypeptidase T, SULFATE ION, ... Authors: Timofeev, V.I, Dorovatovskii, P.V, Lazarenko, V.A, Akparov, V.K, Kuranova, I.P. Deposit date: 2023-10-18 Release date: 2024-01-17 Method: X-RAY DIFFRACTION (1.96 Å) Cite: L211Q, L254N, T262G mutant of carboxypeptidase T from Thermoactinomyces vulgaris To Be Published
5ZEQ	Carboxypeptidase B in complex with DD28 Descriptor: (2~{S})-2-[(6-azanyl-5-chloranyl-pyridin-3-yl)methyl]-3-selanyl-propanoic acid, CACODYLATE ION, Carboxypeptidase B, ... Authors: Itoh, T, Yoshimoto, N, Yamamoto, K. Deposit date: 2018-02-27 Release date: 2018-06-20 Last modified: 2018-07-04 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural basis for the selective inhibition of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) by a selenium-containing inhibitor with chloro-aminopyridine as a basic group Bioorg. Med. Chem. Lett., 28, 2018
6CPA	CRYSTAL STRUCTURE OF THE COMPLEX OF CARBOXYPEPTIDASE A WITH A STRONGLY BOUND PHOSPHONATE IN A NEW CRYSTALLINE FORM: COMPARISON WITH STRUCTURES OF OTHER COMPLEXES Descriptor: CARBOXYPEPTIDASE A, O-(((1R)-((N-PHENYLMETHOXYCARBONYL-L-ALANYL)AMINO)ETHYL)HYDROXYPHOSPHONO)-L-BENZYLACETIC ACID, ZINC ION Authors: Kim, H, Lipscomb, W.N. Deposit date: 1990-02-15 Release date: 1991-10-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of the complex of carboxypeptidase A with a strongly bound phosphonate in a new crystalline form: comparison with structures of other complexes. Biochemistry, 29, 1990
2JEW	Crystal structure of ((2S)-5-amino-2-((1-n-propyl-1H-imidazol-4-yl) methyl)pentanoic acid) UK396,082 a TAFIa inhibitor, Bound to Activated Porcine Pancreatic carboxypeptidaseB Descriptor: (2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]PENTANOIC ACID, CARBOXYPEPTIDASE B, ZINC ION Authors: Brown, D.G, Moore, R.S. Deposit date: 2007-01-24 Release date: 2007-11-20 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis. J. Med. Chem., 50, 2007
2RFH	Crystal Structure Analysis of CPA-2-benzyl-3-nitropropanoic acid complex Descriptor: (2R)-2-benzyl-3-nitropropanoic acid, Carboxypeptidase A1, ZINC ION Authors: Wang, S.-F, Zeng, Z.-H. Deposit date: 2007-09-29 Release date: 2008-04-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A Bioorg.Med.Chem., 16, 2008
4Z65	Carboxypeptidase B with Sulphamoil Arginine Descriptor: Carboxypeptidase B, N~2~-sulfamoyl-L-arginine, ZINC ION Authors: Timofeev, V.I, Akparov, V.K, Kuranova, I.P. Deposit date: 2015-04-03 Release date: 2015-10-14 Last modified: 2015-10-28 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Structure of the complex of carboxypeptidase B and N-sulfamoyl-L-arginine. Acta Crystallogr.,Sect.F, 71, 2015
3QNV	Carboxypeptidase T Descriptor: Carboxypeptidase T, GLYCEROL, SULFATE ION, ... Authors: Timofeev, V.I, Akparov, V.K, Kuranova, I.P. Deposit date: 2011-02-09 Release date: 2012-02-15 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Three-dimensional structure of recombinant carboxypeptidase T from Thermoactinomyces vulgaris without calcium ions Crystallography Reports, 56, 2011
7AQP	T262S, A251S, L254S, L211Q mutant of carboxypeptidase T from Thermoactinomyces vulgaris Descriptor: CALCIUM ION, Carboxypeptidase T, SULFATE ION, ... Authors: Timofeev, V.I, Akparov, V.K, Kuranova, I.P. Deposit date: 2020-10-22 Release date: 2020-12-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.6 Å) Cite: T262S, A251S, L254S, L211Q mutant of carboxypeptidase T from Thermoactinomyces vulgaris To Be Published
7ARU	L254N mutant of carboxypeptidase T from Thermoactinomyces vulgaris N-sulfamoyl-L-valine Descriptor: (2~{S})-3-methyl-2-(sulfamoylamino)butanoic acid, CALCIUM ION, Carboxypeptidase T, ... Authors: Timofeev, V.I, Akparov, V.K, Kuranova, I.P. Deposit date: 2020-10-26 Release date: 2020-11-11 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.05 Å) Cite: L254N mutant of carboxypeptidase T from Thermoactinomyces vulgaris N-sulfamoyl-L-valine To Be Published
6I6Z	Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Tyr-Ala-Y(PO2CH2)-homoPhe-OH Descriptor: (2S)-2-{[(S)-{(1R)-1-[(N-acetyl-L-tyrosyl)amino]ethyl}(hydroxy)phosphoryl]methyl}-4-phenylbutanoic acid, Carboxypeptidase A1, ZINC ION Authors: Gallego, P, Reverter, D. Deposit date: 2018-11-15 Release date: 2018-12-12 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes. J. Med. Chem., 62, 2019
6GO2	Carboxypeptidase T with N-sulfamoyl-L-Leucine Descriptor: CALCIUM ION, Carboxypeptidase T, SULFATE ION, ... Authors: Timofeev, V.I, Akparov, V.K, Kuranova, I.P. Deposit date: 2018-06-01 Release date: 2018-06-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Carboxypeptidase T with N-sulfamoyl-L-Leucine To Be Published
5CPA	REFINED CRYSTAL STRUCTURE OF CARBOXYPEPTIDASE A AT 1.54 ANGSTROMS RESOLUTION. Descriptor: CARBOXYPEPTIDASE A, ZINC ION Authors: Lipscomb, W.N. Deposit date: 1982-05-06 Release date: 1982-07-29 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Refined crystal structure of carboxypeptidase A at 1.54 A resolution. J.Mol.Biol., 168, 1983
3PRT	Mutant of the Carboxypeptidase T Descriptor: CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... Authors: Timofeev, V.I, Akparov, V.K, Grishin, A.M, Kuranova, I.P. Deposit date: 2010-11-30 Release date: 2011-11-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.66 Å) Cite:
2V77	Crystal Structure of Human Carboxypeptidase A1 Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CARBOXYPEPTIDASE A1, OCTANE-1,3,5,7-TETRACARBOXYLIC ACID, ... Authors: Pallares, I, Fernandez, D, Comellas-Bigler, M, Fernandez-Recio, J, Ventura, S, Aviles, F.X, Vendrell, J. Deposit date: 2007-07-27 Release date: 2008-07-01 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.603 Å) Cite: Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid). Acta Crystallogr. D Biol. Crystallogr., D64, 2008
4OKO	Crystal structure of Francisella tularensis REP34 (Rapid Encystment Phenotype Protein 34 KDa) Descriptor: ACETATE ION, Rapid Encystment Phenotype Protein 34 KDa, ZINC ION Authors: Feld, G.K, Segelke, B.W, Corzett, M.H, Hunter, M.S, Frank, M, Rasley, A. Deposit date: 2014-01-22 Release date: 2014-09-24 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.053 Å) Cite: Structure and Function of REP34 Implicates Carboxypeptidase Activity in Francisella tularensis Host Cell Invasion. J.Biol.Chem., 289, 2014
6F79	Carboxypeptidase T mutant L211Q with Sulphamoil Arginine Descriptor: CALCIUM ION, Carboxypeptidase T, N~2~-sulfamoyl-L-arginine, ... Authors: Timofeev, V.I, Akparov, V.K, Kuranova, I.P. Deposit date: 2017-12-07 Release date: 2018-08-15 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Carboxypeptidase T mutant L211Q with Sulphamoil Arginine To Be Published
7CPA	COMPARISON OF THE STRUCTURES OF THREE CARBOXYPEPTIDASE A-PHOSPHONATE COMPLEXES DETERMINED BY X-RAY CRYSTALLOGRAPHY Descriptor: CARBOXYPEPTIDASE A, O-((((N-PHENYL-METHOXY-CARBONYL)-PHENYL ALANYL-CARBONYL)AMINO)-ISOBUTYL)HYDROXY PHOSPHINYL)-3-PHENYLACETIC ACID, ZINC ION Authors: Kim, H, Lipscomb, W.N. Deposit date: 1991-05-21 Release date: 1994-01-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2 Å) Cite: Comparison of the structures of three carboxypeptidase A-phosphonate complexes determined by X-ray crystallography. Biochemistry, 30, 1991
6SN6	CARBOXYPEPTIDASE T WITH N-SULFAMOYL-L-GLUTAMIC ACID Descriptor: CALCIUM ION, Carboxypeptidase T, N-sulfamoyl-L-glutamic acid, ... Authors: Timofeev, V.I, Akparov, V.K, Kuranova, I.P. Deposit date: 2019-08-23 Release date: 2019-10-09 Method: X-RAY DIFFRACTION (1.93 Å) Cite: CARBOXYPEPTIDASE T WITH N-SULFAMOYL-L-GLUTAMIC ACID To Be Published
6F75	Carboxypeptidase T mutant L254N with Sulphamoil Leucine Descriptor: CALCIUM ION, Carboxypeptidase T, SULFATE ION, ... Authors: Timofeev, V.I, Akparov, V.K, Kuranova, I.P. Deposit date: 2017-12-07 Release date: 2018-08-15 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Carboxypeptidase T mutant L254N with Sulphamoil Leucine To Be Published
6F6Q	Carboxypeptidase T mutant L254N with Sulphamoil Arginine Descriptor: CALCIUM ION, Carboxypeptidase T, N~2~-sulfamoyl-L-arginine, ... Authors: Timofeev, V.I, Akparov, V.K, Kuranova, I.P. Deposit date: 2017-12-06 Release date: 2018-08-15 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Carboxypeptidase T mutant L254N with Sulphamoil Arginine To Be Published

 

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