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4XL9
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BU of 4xl9 by Molmil
Tailspike protein mutant D339A of E. coli bacteriophage HK620
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ...
Authors:Gohlke, U, Broeker, N.K, Heinemann, U, Seckler, R, Barbirz, S.
Deposit date:2015-01-13
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Enthalpic cost of water removal from a hydrophobic glucose binding cavity on HK620 tailspike protein.
to be published
2MY2
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BU of 2my2 by Molmil
Snu17p-Bud13p structure intermediate during RES complex assembly
Descriptor: Pre-mRNA-splicing factor CWC26, U2 snRNP component IST3
Authors:Wysoczanski, P, Becker, S, Zweckstetter, M.
Deposit date:2015-01-19
Release date:2015-08-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structures of intermediates during RES complex assembly.
Sci Rep, 5, 2015
4XSV
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BU of 4xsv by Molmil
Human CTP: Phosphoethanolamine Cytidylyltransferase in complex with CTP
Descriptor: CYTIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, Ethanolamine-phosphate cytidylyltransferase, ...
Authors:Schuler, H, Karlberg, T.
Deposit date:2015-01-22
Release date:2016-03-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Human CTP: Phosphoethanolamine Cytidylyltransferase
To Be Published
6A9W
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BU of 6a9w by Molmil
Structure of the bifunctional DNA primase-polymerase from phage NrS-1
Descriptor: Primase
Authors:Guo, H.J, Li, M.J, Wang, T.L, Wu, H, Zhou, H, Xu, C.Y, Liu, X.P, Yu, F, He, J.H.
Deposit date:2018-07-16
Release date:2019-03-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure and biochemical studies of the bifunctional DNA primase-polymerase from phage NrS-1.
Biochem. Biophys. Res. Commun., 510, 2019
6AAQ
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BU of 6aaq by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with BCNLys
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, N6-({[(1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl]methoxy}carbonyl)-L-lysine, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-18
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.551 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
4XCX
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BU of 4xcx by Molmil
METHYLTRANSFERASE DOMAIN OF SMALL RNA 2'-O-METHYLTRANSFERASE
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, Small RNA 2'-O-methyltransferase
Authors:Walker, J.R, Zeng, H, Dong, A, Li, Y, Wernimont, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2014-12-18
Release date:2015-01-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Crystal structure of human C1ORF59 in complex with SAH
To be published
2MQO
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BU of 2mqo by Molmil
Structural Investigation of hnRNP L bound to RNA
Descriptor: Protein Hnrnpl, RNA (5'-R(*CP*AP*CP*AP*CP*A)-3')
Authors:Blatter, M, Allain, F.
Deposit date:2014-06-24
Release date:2015-12-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Investigation of hnRNP L bound to RNA
To be Published
2MZE
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BU of 2mze by Molmil
NMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7)
Descriptor: CALCIUM ION, Matrilysin, ZINC ION
Authors:Prior, S.H, Fulcher, Y.G, Van Doren, S.R.
Deposit date:2015-02-11
Release date:2015-11-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Charge-Triggered Membrane Insertion of Matrix Metalloproteinase-7, Supporter of Innate Immunity and Tumors.
Structure, 23, 2015
2N3T
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BU of 2n3t by Molmil
Solution structure of the Rpn1 substrate receptor site toroid 1 (T1)
Descriptor: 26S proteasome regulatory subunit RPN1
Authors:Chen, X, Walters, K.J.
Deposit date:2015-06-10
Release date:2016-02-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome.
Science, 351, 2016
6AEF
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BU of 6aef by Molmil
PapA2 acyl transferase
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Trehalose-2-sulfate acyltransferase PapA2, ...
Authors:Chaudhary, S, Rao, V, Panchal, V.
Deposit date:2018-08-04
Release date:2019-06-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:A novel mutation alters the stability of PapA2 resulting in the complete abrogation of sulfolipids in clinical mycobacterial strains.
Faseb Bioadv, 1, 2019
6AAN
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BU of 6aan by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mEtZLys
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Yanagisawa, T, Kuratani, M, Yokoyama, S.
Deposit date:2018-07-18
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
4XW0
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BU of 4xw0 by Molmil
Crystal structure of (GCCU(G-LNA)CCUGC)2 duplex
Descriptor: RNA (5'-R(*GP*CP*CP*UP*(LCG)P*CP*CP*UP*GP*C)-3'), SULFATE ION
Authors:Kiliszek, A, Banaszak, K, Rypniewski, W.
Deposit date:2015-01-28
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Watson-Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation.
Rna, 22, 2016
2N03
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BU of 2n03 by Molmil
Solution NMR Structure plectin repeat domain 6 (4403-4606) of Plectin from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR6354E
Descriptor: Plectin
Authors:Pulavarti, S, Eletsky, A, Huang, Y, Janjua, H, Xiao, R, Acton, T, Everett, J, Montelione, G, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-03-04
Release date:2015-05-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR Structure plectin repeat domain 6 (4403-4606) of Plectin from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR6354E
To be Published
6AHU
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BU of 6ahu by Molmil
Cryo-EM structure of human Ribonuclease P with mature tRNA
Descriptor: H1 RNA, Ribonuclease P protein subunit p14, Ribonuclease P protein subunit p20, ...
Authors:Wu, J, Niu, S, Tan, M, Lan, P, Lei, M.
Deposit date:2018-08-20
Release date:2018-12-05
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Cryo-EM Structure of the Human Ribonuclease P Holoenzyme.
Cell, 175, 2018
4XM0
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BU of 4xm0 by Molmil
N,N'-diacetylchitobiose deacetylase (SeMet derivative) from Pyrococcus furiosus in the absence of cadmium
Descriptor: Uncharacterized protein, ZINC ION
Authors:Nakamura, T, Niiyama, M, Hashimoto, W, Ida, K, Uegaki, K.
Deposit date:2015-01-14
Release date:2015-06-10
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Multiple crystal forms of N,N'-diacetylchitobiose deacetylase from Pyrococcus furiosus.
Acta Crystallogr.,Sect.F, 71, 2015
2MVW
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BU of 2mvw by Molmil
Solution structure of the TRIM19 B-box1 (B1) of human promyelocytic leukemia (PML)
Descriptor: Protein PML, ZINC ION
Authors:Huang, S, Naik, M.T, Fan, P, Wang, Y, Chang, C, Huang, T.
Deposit date:2014-10-17
Release date:2014-11-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The B-box 1 dimer of human promyelocytic leukemia protein.
J.Biomol.Nmr, 60, 2014
4XYJ
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BU of 4xyj by Molmil
Crystal structure of human phosphofructokinase-1 in complex with ATP and Mg, Northeast Structural Genomics Consortium Target HR9275
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent 6-phosphofructokinase, platelet type, ...
Authors:Forouhar, F, Webb, B.A, Szu, F.-E, Seetharaman, J, Barber, D.L, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-02-02
Release date:2015-05-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations.
Nature, 523, 2015
2N8H
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BU of 2n8h by Molmil
Structural basis for the inhibition of voltage-gated sodium channels with conotoxin-muOxi-GVIIJ
Descriptor: conotoxin-muOxi-GVIIJ
Authors:Green, B.R, Chhabra, S, Norton, R.S.
Deposit date:2015-10-15
Release date:2016-02-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin mu O-GVIIJ.
J.Biol.Chem., 291, 2016
4XOR
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BU of 4xor by Molmil
Tailspike protein double mutant D339N/E372Q of E. coli bacteriophage HK620 in complex with pentasaccharide
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ...
Authors:Gohlke, U, Broeker, N.K, Heinemann, U, Seckler, R, Barbirz, S.
Deposit date:2015-01-16
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Enthalpic cost of water removal from a hydrophobic glucose binding cavity on HK620 tailspike protein.
to be published
4Y2Q
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BU of 4y2q by Molmil
Structure of soluble epoxide hydrolase in complex with 1-[3-(trifluoromethyl)pyridin-2-yl]piperazine
Descriptor: 1-[3-(trifluoromethyl)pyridin-2-yl]piperazine, Bifunctional epoxide hydrolase 2, MAGNESIUM ION
Authors:Amano, Y, Yamaguchi, T.
Deposit date:2015-02-10
Release date:2015-05-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Identification of N-ethylmethylamine as a novel scaffold for inhibitors of soluble epoxide hydrolase by crystallographic fragment screening
Bioorg.Med.Chem., 23, 2015
4Y35
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BU of 4y35 by Molmil
Endothiapepsin in complex with fragment 290
Descriptor: 4-chlorobenzyl carbamimidothioate, ACETATE ION, DIMETHYL SULFOXIDE, ...
Authors:Wang, X, Heine, A, Klebe, G.
Deposit date:2015-02-10
Release date:2016-03-02
Method:X-RAY DIFFRACTION (1.457 Å)
Cite:Crystallographic Fragment Screening of an Entire Library
To Be Published
2NB8
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BU of 2nb8 by Molmil
Solution structure of C-terminal extramembrane domain of SH protein
Descriptor: Small hydrophobic protein
Authors:Li, Y, To, J, Surya, W, Torres, J.
Deposit date:2016-01-26
Release date:2016-02-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Inhibition of the human respiratory syncytial virus small hydrophobic protein and structural variations in a bicelle environment.
J.Virol., 88, 2014
5ZU7
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BU of 5zu7 by Molmil
Crystal structure of MERS-CoV macro domain in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, ORF1a
Authors:Lin, M.-H, Cho, C.-C, Chien, C.-Y, Hsu, C.-H.
Deposit date:2018-05-07
Release date:2019-06-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.705 Å)
Cite:Crystal structure of MERS-CoV macro domain in complex with AMP
To Be Published
2MW2
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BU of 2mw2 by Molmil
Hha-H-NS46 charge zipper complex
Descriptor: DNA-binding protein H-NS, Hemolysin expression-modulating protein Hha
Authors:Cordeiro, T.N, Garcia, J, Bernado, P, Millet, O, Pons, M.
Deposit date:2014-10-24
Release date:2015-07-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A Three-protein Charge Zipper Stabilizes a Complex Modulating Bacterial Gene Silencing.
J. Biol. Chem., 290, 2015
5ZRZ
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BU of 5zrz by Molmil
Crystal Structure of EphA5/SAMD5 Complex
Descriptor: Ephrin type-A receptor 5, Sterile alpha motif domain-containing protein 5
Authors:Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M.
Deposit date:2018-04-25
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018

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