8WI4
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![BU of 8wi4 by Molmil](/molmil-images/mine/8wi4) | m6-hMRP5 inward open | Descriptor: | ATP-binding cassette sub-family C member 5 | Authors: | Liu, Z.M, Huang, Y. | Deposit date: | 2023-09-24 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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9FST
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![BU of 9fst by Molmil](/molmil-images/mine/9fst) | Yeast 20S proteasome with human beta1i (1-51) in complex with epoxyketone inhibitor LU-001i | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Maurits, E, Huber, E.M, Dekker, P.M, Wang, X, Heinemeyer, W, Florea, B.I, Groll, M, Overkleeft, H.S. | Deposit date: | 2024-06-21 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites To Be Published
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8VKU
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![BU of 8vku by Molmil](/molmil-images/mine/8vku) | Structure of VCP in complex with an ATPase activator (D2 domains only, hexameric form) | Descriptor: | (3R)-N-[2-(ethylsulfanyl)phenyl]-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)butanamide, Transitional endoplasmic reticulum ATPase | Authors: | Jones, N.H, Urnivicius, L, Kapoor, T.M. | Deposit date: | 2024-01-09 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry. Proc.Natl.Acad.Sci.USA, 121, 2024
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9B3D
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![BU of 9b3d by Molmil](/molmil-images/mine/9b3d) | mDia1 in the middle of F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Palmer, N.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2024-03-19 | Release date: | 2024-05-29 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Mechanisms of actin filament severing and elongation by formins. Nature, 632, 2024
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8WNH
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![BU of 8wnh by Molmil](/molmil-images/mine/8wnh) | |
9B3R
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![BU of 9b3r by Molmil](/molmil-images/mine/9b3r) | The structure of human cardiac F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | Authors: | Doran, M.H, Sousa, D, Rynkiewicz, M.J, Lehman, W, Cammarato, A. | Deposit date: | 2024-03-20 | Release date: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of human cardiac actin To Be Published
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8Z3B
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![BU of 8z3b by Molmil](/molmil-images/mine/8z3b) | Crystal structure of GSTd2 | Descriptor: | Glutathione S-transferase delta | Authors: | Mo, X, Yao, Y. | Deposit date: | 2024-04-15 | Release date: | 2024-07-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Characterization of a Plutella xylostella GZTd2, evolved in isothiocyanate detoxification To be published
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8YL9
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![BU of 8yl9 by Molmil](/molmil-images/mine/8yl9) | Crystal structures of terpene synthases complexed with a substrate mimic | Descriptor: | MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, PYROPHOSPHATE, ... | Authors: | Xu, M, Ma, M. | Deposit date: | 2024-03-05 | Release date: | 2024-04-24 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Insights Into the Terpene Cyclization Domains of Two Fungal Sesterterpene Synthases and Enzymatic Engineering for Sesterterpene Diversification. Angew.Chem.Int.Ed.Engl., 63, 2024
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8XN4
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8ZWM
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8XM2
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9BB5
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![BU of 9bb5 by Molmil](/molmil-images/mine/9bb5) | |
8YHH
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![BU of 8yhh by Molmil](/molmil-images/mine/8yhh) | The Crystal Structure of Mitotic Kinesin Eg5 from Biortus | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Wang, F, Cheng, W, Lv, Z, Qi, J, Wu, B. | Deposit date: | 2024-02-28 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Crystal Structure of Mitotic Kinesin Eg5 from Biortus To Be Published
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9BIY
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9FE5
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![BU of 9fe5 by Molmil](/molmil-images/mine/9fe5) | Crystal Structure of NuoEF variant R66G(NuoF) from Aquifex aeolicus bound to NADH under anoxic conditions after 10 min soaking | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, CHLORIDE ION, ... | Authors: | Wohlwend, D, Friedrich, T, Goeppert-Asadollahpour, S. | Deposit date: | 2024-05-17 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural robustness of the NADH binding site in NADH:ubiquinone oxidoreductase (complex I). Biochim Biophys Acta Bioenerg, 1865, 2024
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8OQK
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![BU of 8oqk by Molmil](/molmil-images/mine/8oqk) | Crystal structure of Tannerella forsythia sugar kinase K1058 | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, N-acetylglucosamine kinase | Authors: | Gogler, K, Fink, P, Stasiak, A.C, Stehle, T, Zocher, G. | Deposit date: | 2023-04-12 | Release date: | 2023-08-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | N-acetylmuramic acid recognition by MurK kinase from the MurNAc auxotrophic oral pathogen Tannerella forsythia. J.Biol.Chem., 299, 2023
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8XV2
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![BU of 8xv2 by Molmil](/molmil-images/mine/8xv2) | Thiamine-bound human SLC19A3 | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Soluble cytochrome b562,Thiamine transporter 2 | Authors: | Dang, Y, Wang, G.P, Zhang, Z. | Deposit date: | 2024-01-14 | Release date: | 2024-03-27 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Substrate and drug recognition mechanisms of SLC19A3. Cell Res., 34, 2024
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9EOH
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8ZWI
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![BU of 8zwi by Molmil](/molmil-images/mine/8zwi) | |
8XVZ
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![BU of 8xvz by Molmil](/molmil-images/mine/8xvz) | |
9BB7
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![BU of 9bb7 by Molmil](/molmil-images/mine/9bb7) | |
8XAV
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![BU of 8xav by Molmil](/molmil-images/mine/8xav) | Cryo-EM structure of an anti-phage defense complex | Descriptor: | ATP-binding protein, DUF4297 | Authors: | Wang, Y, Deng, Z. | Deposit date: | 2023-12-05 | Release date: | 2024-06-05 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex. Cell Res., 34, 2024
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9BKG
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8ZKV
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8P5P
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![BU of 8p5p by Molmil](/molmil-images/mine/8p5p) | Structure of TECPR1 N-terminal DysF domain | Descriptor: | GLYCEROL, Tectonin beta-propeller repeat-containing protein 1 | Authors: | Boyle, K.B, Elliott, P.R, Randow, F. | Deposit date: | 2023-05-24 | Release date: | 2023-07-19 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | TECPR1 conjugates LC3 to damaged endomembranes upon detection of sphingomyelin exposure. Embo J., 42, 2023
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