PDB: 289 resultsInfo pagesStatus searchChemie searchBIRD

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4XLR	Crystal structure of T.aquaticus transcription initiation complex with CarD containing bubble promoter and RNA Descriptor: CarD-like transcriptional regulator, DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Bae, B, Darst, S.A. Deposit date: 2015-01-13 Release date: 2015-09-23 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (4.3 Å) Cite: CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex. Elife, 4, 2015
4XLN	Crystal structure of T. aquaticus transcription initiation complex containing bubble promoter and RNA Descriptor: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Bae, B, Darst, S.A. Deposit date: 2015-01-13 Release date: 2015-09-23 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (4 Å) Cite: Structure of a bacterial RNA polymerase holoenzyme open promoter complex. Elife, 4, 2015
4ZH2	Crystal structure of Escherichia coli RNA polymerase in complex with CBR703 Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Feng, Y, Ebright, R.H. Deposit date: 2015-04-24 Release date: 2015-08-05 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (4.204 Å) Cite: Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. Structure, 23, 2015
6P1K	Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-05-20 Release date: 2020-02-26 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.05 Å) Cite: E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
6P18	Q21 transcription antitermination complex: loading complex Descriptor: DNA (67-MER) fragment carrying phage-21 pR' promoter and pause element, nontemplate strand, template strand, ... Authors: Yin, Z, Ebright, R.H. Deposit date: 2019-05-19 Release date: 2019-06-26 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis of Q-dependent antitermination. Proc.Natl.Acad.Sci.USA, 116, 2019
6P70	X-ray crystal structure of bacterial RNA polymerase and pyrBI promoter complex Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*TP*CP*TP*TP*TP*GP*CP*CP*GP*GP*G)-3'), DNA (5'-D(P*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*TP*CP*CP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-06-04 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.052 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6P71	X-ray crystal structure of a bacterial reiterative transcription complex of pyrBI promoter Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*GP*CP*CP*GP*GP*GP*A)-3'), DNA (5'-D(P*CP*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*T)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-06-04 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.92 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6PSU	Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi2) with TraR and rpsT P2 promoter Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-07-13 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6PSR	Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1) with TraR and rpsT P2 promoter Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-07-13 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6PSW	Escherichia coli RNA polymerase promoter unwinding intermediate (TRPo) with TraR and rpsT P2 promoter Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-07-13 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6PSS	Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5a) with TraR and mutant rpsT P2 promoter Descriptor: DNA (85-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-07-13 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6PSQ	Escherichia coli RNA polymerase closed complex (TRPc) with TraR and rpsT P2 promoter Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-07-13 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6PST	Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5b) with TraR and mutant rpsT P2 promoter Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-07-13 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3 Å) Cite: Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6PSV	Escherichia coli RNA polymerase promoter unwinding intermediate (TpreRPo) with TraR and rpsT P2 promoter Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-07-13 Release date: 2020-03-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6OY5	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 3 min Descriptor: DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*CP*TP*CP*TP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*CP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*AP*T)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-14 Release date: 2019-06-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OUL	Cryo-EM structure of Escherichia coli RNAP polymerase bound to rpsTP2 promoter DNA Descriptor: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. Deposit date: 2019-05-04 Release date: 2020-02-26 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
6OW3	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1T Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*TP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-09 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.766 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OY6	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 5 min Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*GP*AP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-14 Release date: 2019-06-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.096 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OY7	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 7 min Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-14 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.04 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OVY	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1C Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*CP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-08 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.999 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OVR	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1G Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*GP*GP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*GP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Shin, Y, Murakami, K.S. Deposit date: 2019-05-08 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.843 Å) Cite: Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6UU6	E. coli sigma-S transcription initiation complex with a 4-nt RNA and a UTP ("Old" crystal soaked with UTP, ddCTP, and dinucleotide ApG for 30 minutes) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.201 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UU1	E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Fresh" crystal soaked with CTP, GTP, and ddTTP for 30 minutes) Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.097 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UTZ	E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Fresh" crystal soaked with CTP and UTP for 30 minutes) Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.803 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UU8	E. coli mutant sigma-S transcription initiation complex with a 7-nt RNA ("Fresh" mutant crystal soaked with GTP, UTP, and CTP for 30 minutes) Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zuo, Y, De, S, Steitz, T.A. Deposit date: 2019-10-30 Release date: 2020-08-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.4 Å) Cite: Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020

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