5AVL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5avl by Molmil](/molmil-images/mine/5avl) | Crystal structure of LXRalpha in complex with tert-butyl benzoate analog, compound 32b | Descriptor: | 2-[4-[4-[[2-[(2-methylpropan-2-yl)oxycarbonyl]-3-oxidanyl-4-(trifluoromethyl)phenyl]methoxy]phenyl]phenyl]ethanoic acid, Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha | Authors: | Matsui, Y, Hanzawa, H, Tamaki, K. | Deposit date: | 2015-06-17 | Release date: | 2015-08-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Discovery and structure-guided optimization of tert-butyl 6-(phenoxymethyl)-3-(trifluoromethyl)benzoates as liver X receptor agonists Bioorg.Med.Chem.Lett., 25, 2015
|
|
1DDV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ddv by Molmil](/molmil-images/mine/1ddv) | CRYSTAL STRUCTURE OF THE HOMER EVH1 DOMAIN WITH BOUND MGLUR PEPTIDE | Descriptor: | GLGF-DOMAIN PROTEIN HOMER, METABOTROPIC GLUTAMATE RECEPTOR MGLUR5 | Authors: | Beneken, J, Tu, J.C, Xiao, B, Worley, P.F, Leahy, D.J. | Deposit date: | 1999-11-11 | Release date: | 2000-05-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition. Neuron, 26, 2000
|
|
1LI3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1li3 by Molmil](/molmil-images/mine/1li3) | T4 lysozyme mutant L99A/M102Q bound by 3-chlorophenol | Descriptor: | 3-CHLOROPHENOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K. | Deposit date: | 2002-04-17 | Release date: | 2002-05-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A Model Binding Site for Testing Scoring Functions in Molecular Docking J.Mol.Biol., 322, 2002
|
|
1LI6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1li6 by Molmil](/molmil-images/mine/1li6) | T4 lysozyme mutant L99A/M102Q bound by 5-methylpyrrole | Descriptor: | 5-METHYLPYRROLE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K. | Deposit date: | 2002-04-17 | Release date: | 2002-05-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Model Binding Site for Testing Scoring Functions in Molecular Docking J.Mol.Biol., 322, 2002
|
|
2BC3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bc3 by Molmil](/molmil-images/mine/2bc3) | T7-tagged full-length streptavidin | Descriptor: | GLYCEROL, SULFATE ION, Streptavidin | Authors: | Stenkamp, R.E, Le Trong, I, Ward, T.R, Humbert, N. | Deposit date: | 2005-10-18 | Release date: | 2005-10-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Crystallographic Analysis of a Full-length Streptavidin with Its C-terminal Polypeptide Bound in the Biotin Binding Site. J.Mol.Biol., 356, 2006
|
|
1KRJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1krj by Molmil](/molmil-images/mine/1krj) | Engineering Calcium-binding site into Cytochrome c Peroxidase (CcP) | Descriptor: | Cytochrome c Peroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Bonagura, C.A, Bhaskar, B, Sundaramoorthy, M, Poulos, T.L. | Deposit date: | 2002-01-09 | Release date: | 2002-01-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Conversion of an engineered potassium-binding site into a calcium-selective site in cytochrome c peroxidase. J.Biol.Chem., 274, 1999
|
|
3UGB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ugb by Molmil](/molmil-images/mine/3ugb) | UbcH5c~Ubiquitin Conjugate | Descriptor: | GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3 | Authors: | Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S. | Deposit date: | 2011-11-02 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates. Biochemistry, 51, 2012
|
|
4HWT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hwt by Molmil](/molmil-images/mine/4hwt) | |
1AX0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ax0 by Molmil](/molmil-images/mine/1ax0) | |
9B5M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9b5m by Molmil](/molmil-images/mine/9b5m) | |
9B5F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9b5f by Molmil](/molmil-images/mine/9b5f) | |
9B5S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9b5s by Molmil](/molmil-images/mine/9b5s) | |
9B5C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9b5c by Molmil](/molmil-images/mine/9b5c) | |
9B5Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9b5q by Molmil](/molmil-images/mine/9b5q) | |
9B5O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9b5o by Molmil](/molmil-images/mine/9b5o) | |
9B5N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9b5n by Molmil](/molmil-images/mine/9b5n) | |
9B5U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9b5u by Molmil](/molmil-images/mine/9b5u) | |
9B5L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9b5l by Molmil](/molmil-images/mine/9b5l) | |
9B5X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9b5x by Molmil](/molmil-images/mine/9b5x) | |
9B5H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9b5h by Molmil](/molmil-images/mine/9b5h) | |
9B5V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9b5v by Molmil](/molmil-images/mine/9b5v) | |
8I4U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i4u by Molmil](/molmil-images/mine/8i4u) | Cryo-EM structure of 5-subunit Smc5/6 hinge region | Descriptor: | E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, Structural maintenance of chromosomes protein 6 | Authors: | Qian, L, Jun, Z, Xiang, Z, Wang, Z, Tong, C, Duo, J, Zhenguo, C, Wang, L. | Deposit date: | 2023-01-21 | Release date: | 2024-06-26 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (6.73 Å) | Cite: | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
|
|
1G3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g3d by Molmil](/molmil-images/mine/1g3d) | BOVINE BETA-TRYPSIN BOUND TO META-AMIDINO SCHIFF BASE COPPER (II) CHELATE | Descriptor: | 2-(5-CARBAMIMIDOYL-2-HYDROXY-BENZYLAMINO)-PROPIONIC ACID, BETA-TRYPSIN, CALCIUM ION, ... | Authors: | Toyota, E, Ng, K.K.S, Sekizaki, H, Itoh, K, Tanizawa, K, James, M.N.G. | Deposit date: | 2000-10-23 | Release date: | 2001-01-17 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray crystallographic analyses of complexes between bovine beta-trypsin and Schiff base copper(II) or iron(III) chelates. J.Mol.Biol., 305, 2001
|
|
8FFY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ffy by Molmil](/molmil-images/mine/8ffy) | Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA(UGA-TL) | Descriptor: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, Serine--tRNA ligase, mitochondrial, ... | Authors: | Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G. | Deposit date: | 2022-12-11 | Release date: | 2023-08-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for a degenerate tRNA identity code and the evolution of bimodal specificity in human mitochondrial tRNA recognition. Nat Commun, 14, 2023
|
|
4LXB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lxb by Molmil](/molmil-images/mine/4lxb) | Crystal Structure Analysis of thrombin in complex with compound D58 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-difluoromethoxy-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-((S)-3-dimethylamino-pyrrolidin-1-yl)-3-oxo-propyl]-amide, Hirudin variant-1, ... | Authors: | Stehlin-Gaon, C, Bocskei, Z. | Deposit date: | 2013-07-29 | Release date: | 2014-06-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | 5-Chlorothiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a selective and potent orally active dual thrombin and factor Xa inhibitor. J.Med.Chem., 56, 2013
|
|